Biological sciences topic list of research papers
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A lack of confirmation with alternative assays questions the validity of IL-17A expression in human neutrophils using immunohistochemistry
Abstract We identified IL-17A-positive neutrophils in Wolbachia-positive Onchocerca volvulus nodules using an antibody that has previously reported IL-17A-positive neutrophils in several inflammatory conditions. However, we could not detect IL-17A...
2014 / Francesca Tamarozzi, Helen L. Wright, Huw B. Thomas, Steven W. Edwards, Mark J. Taylor -
Overexpression of Medicago sativa TMT elevates the α-tocopherol content in Arabidopsis seeds, alfalfa leaves, and delays dark-induced leaf senescence
Abstract Alfalfa (Medicago sativa L.) is a major forage legume for livestock and a target for improving their dietary quality. Vitamin E is an essential vitamin that animals must obtain from their diet for proper growth and development. γ-tocopherol ...
2016 / Jishan Jiang, Huili Jia, Guangyan Feng, Zan Wang, Jun Li, et al. -
Data set from the proteomic analysis of Bithynia siamensis goniomphalos snails upon infection with the carcinogenic liver fluke Opisthorchis viverrini
Abstract The snail Bithynia siamensis goniomphalos acts as the first intermediate host for the human liver fluke Opisthorchis viverrini, the major cause of cholangiocarcinoma (CCA) in Northeast Thailand. This data article contains...
2014 / Sattrachai Prasopdee, Smarn Tesana, Cinzia Cantacessi, Thewarach Laha, Jason Mulvenna, et al. -
Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress response
Abstract Objective Central administration of ligands for fibroblast growth factor receptors (FGFRs) such as fibroblast growth factor-19 (FGF19) and FGF21 exert glucose-lowering effects in rodent models of obesity and type 2...
2015 / Jennifer M. Rojas, Miles E. Matsen, Thomas O. Mundinger, Gregory J. Morton, Darko Stefanovski, et al. -
Highly sensitive detection of influenza virus in saliva by real-time PCR method using sugar chain-immobilized gold nanoparticles; application to clinical studies
Abstract A highly sensitive and convenient method for detecting influenza virus was developed using modified end-point melt curve analysis of a RT-qPCR SYBR Green method and influenza virus-binding sugar chain-immobilized gold-nanoparticles (SGNP)....
2015 / Yasuo Suda, Mami Nagatomo, Risa Yokoyama, Mami Ohzono, Kazue Aoyama, et al. -
Being relevant: Practical guidance for early career researchers interested in solving conservation problems
Abstract In a human-altered world where biodiversity is in decline and conservation problems abound, there is a dire need to ensure that the next generation of conservation scientists have the knowledge, skills, and training to address these...
2015 / J.M. Chapman, D. Algera, M. Dick, E.E. Hawkins, M.J. Lawrence, et al. -
Delphinidin prevents high glucose-induced cell proliferation and collagen synthesis by inhibition of NOX-1 and mitochondrial superoxide in mesangial cells
Abstract This study examined the effect of delphinidin on high glucose-induced cell proliferation and collagen synthesis in mesangial cells. Glucose dose-dependently (5.6–25 mM) increased cell proliferation and collagen I and IV mRNA levels, whereas ...
2016 / Seung Eun Song, Hye Jun Jo, Yong-Woon Kim, Young-Je Cho, Jae-Ryong Kim, et al. -
Fam40b is required for lineage commitment of murine embryonic stem cells2014 / V Wagh, M X Doss, D Sabour, R Niemann, K Meganathan, et al.
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Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations2015 / M. Geoffrey Hayes, Margrit Urbanek, David A. Ehrmann, Loren L. Armstrong, Ji Young Lee, et al.
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The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis
Summary We identified a dominant missense mutation in the SCN transcription factor Zfhx3, termed short circuit (Zfhx3 Sci ), which accelerates circadian locomotor rhythms in mice....
2015 / Michael J. Parsons, Marco Brancaccio, Siddharth Sethi, Elizabeth S. Maywood, Rahul Satija, et al. -
Yeast expressed ArtinM shares structure, carbohydrate recognition, and biological effects with native ArtinM
Abstract Recent advances in glycobiology have revealed the essential role of lectins in deciphering the glycocodes at the cell surface to generate important biological signaling responses. ArtinM, a d-mannose-binding lectin isolated from the seeds...
2015 / Nerry Tatiana Cecílio, Fernanda Caroline Carvalho, Yan Liu, Martin Moncrieffe, Patrícia Andressa de Almeida Buranello, et al. -
Hidden Genetic Variation in LCA9-Associated Congenital Blindness Explained by 5′UTR Mutations and Copy-Number Variations of NMNAT12015 / Frauke Coppieters, Anne Laure Todeschini, Takuro Fujimaki, Annelot Baert, Marieke De Bruyne, et al.
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Climate-driven spatial mismatches between British orchards and their pollinators: increased risks of pollination deficits2014 / Chiara Polce, Michael P Garratt, Mette Termansen, Julian Ramirez-Villegas, Andrew J Challinor, et al.
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Spotting the differences: Probing host/microbiota interactions with a dedicated software tool for the analysis of faecal outputs in Drosophila
Abstract The intestinal physiology of Drosophila melanogaster can be monitored in an integrative, non-invasive manner by analysing graphical features of the excreta produced by flies fed on a dye-supplemented diet. This assay has been used by...
2014 / Matthew T. Wayland, Arnaud Defaye, Joao Rocha, Satish Arcot Jayaram, Julien Royet, et al. -
A comparison of ceruloplasmin to biological polyanions in promoting the oxidation of Fe2+ under physiologically relevant conditions
Abstract Background Iron oxidation is thought to be predominantly handled enzymatically in the body, to minimize spontaneous combustion with oxygen and to facilitate cellular iron export by loading transferrin. This process may be...
2014 / Bruce X. Wong, Scott Ayton, Linh Q. Lam, Peng Lei, Paul A. Adlard, et al. -
Complete genome sequence of Kangiella koreensis type strain (SW-125T)2009 / Cliff Han, Johannes Sikorski, Alla Lapidus, Matt Nolan, Tijana Glavina Del Rio, et al.
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Life-history implications of the allometric scaling of growth
Abstract Several phenomenological descriptions, such as the von Bertalanffy growth model, have been widely used to describe size-at-age and individual growth across a diverse range of organisms. However, for modelling life histories, as opposed to...
2014 / David S. Boukal, Ulf Dieckmann, Katja Enberg, Mikko Heino, Christian Jørgensen -
Identification of both MT-RNR1 m.1555A>G and bi-allelic GJB2 mutations in probands with non-syndromic hearing loss
Abstract Objectives Mutations in GJB2 and MT-RNR1 are common causes for non-syndromic sensorineural hearing loss (NSHL). In this study, we investigated the co-existence of both MT-RNR1 and bi-allelic GJB2 mutations in a large...
2014 / Yongchuan Chai, Lianhua Sun, Xiuhong Pang, Xiaowen Wang, Dongye Chen, et al. -
SPINE workshop on automated X-ray analysis: a progress report2006 / M. Bahar, C. Ballard, S. X. Cohen, K. D. Cowtan, E. J. Dodson, et al.
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The ω6-fatty acid, arachidonic acid, regulates the conversion of white to brite adipocyte through a prostaglandin/calcium mediated pathway
Abstract Objective Brite adipocytes are inducible energy-dissipating cells expressing UCP1 which appear within white adipose tissue of healthy adult individuals. Recruitment of these cells represents a potential strategy to fight...
2014 / Didier F. Pisani, Rayane A. Ghandour, Guillaume E. Beranger, Pauline Le Faouder, Jean-Claude Chambard, et al.