Biological sciences topic list of research papers
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The Natural Selection of Herpesviruses and Virus-Specific NK Cell Receptors2009 / Joseph C. Sun, Lewis L. Lanier
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Generation of induced pluripotent stem cells (iPSCs) from a Bernard–Soulier syndrome patient carrying a W71R mutation in the GPIX gene
Abstract We generated an induced pluripotent stem cell (iPSC) line from a Bernard–Soulier Syndrome (BSS) patient carrying the mutation p.Trp71Arg in the GPIX locus (BSS1-PBMC-iPS4F4). Peripheral blood mononuclear cells (PBMCs) were reprogrammed...
2016 / Lourdes Lopez-Onieva, Rosa Montes, Mar Lamolda, Tamara Romero, Verónica Ayllon, et al. -
Translating biological findings into new treatment strategies for amyotrophic lateral sclerosis (ALS)
Abstract Amyotrophic lateral sclerosis (ALS) is characterized by the selective death of motor neurons in the motor cortex, brainstem and spinal cord. It is a neurodegenerative disorder with high genetic and phenotypic variability. In most patients,...
2014 / Lindsay Poppe, Laura Rué, Wim Robberecht, Ludo Van Den Bosch -
A Genetic Progression Model of BrafV600E-Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
Summary We show that BRAFV600E initiates an alternative pathway to colorectal cancer (CRC), which progresses through a hyperplasia/adenoma/carcinoma sequence. This pathway underlies significant subsets of CRCs with distinctive...
2013 / Roland Rad, Juan Cadiñanos, Lena Rad, Ignacio Varela, Alexander Strong, et al. -
GIGAS PROPERTIES AND ACREAGE YIELD IN AUTOTETRAPLOID GALEOPSIS PUBESCENS2010 / IVAR EKDAHL
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Mutations in the interleukin receptor IL11RA cause autosomal recessive Crouzon-like craniosynostosis2013 / Katharina Keupp, Yun Li, Ibrahim Vargel, Alexander Hoischen, Rebecca Richardson, et al.
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mTOR plays an important role in cow's milk allergy-associated behavioral and immunological deficits
Abstract Autism spectrum disorder (ASD) is multifactorial, with both genetic as well as environmental factors working in concert to develop the autistic phenotype. Immunological disturbances in autistic individuals have been reported and a role for...
2015 / Jiangbo Wu, Caroline G.M. de Theije, Sofia Lopes da Silva, Hilma van der Horst, Margot T.M. Reinders, et al. -
Minimum information for reporting next generation sequence genotyping (MIRING): Guidelines for reporting HLA and KIR genotyping via next generation sequencing
Abstract The development of next-generation sequencing (NGS) technologies for HLA and KIR genotyping is rapidly advancing knowledge of genetic variation of these highly polymorphic loci. NGS genotyping is poised to replace older methods for clinical ...
2015 / Steven J. Mack, Robert P. Milius, Benjamin D. Gifford, Jürgen Sauter, Jan Hofmann, et al. -
A bacterial protease inhibitor protects antigens delivered in oral vaccines from digestion while triggering specific mucosal immune responses
Abstract We report here that a bacterial protease inhibitor from Brucella spp. called U-Omp19 behaves as an ideal constituent for a vaccine formulation against infectious diseases. When co-administered orally with an antigen (Ag), U-Omp19: i) can...
2015 / Andrés Esteban Ibañez, Lorena Mirta Coria, Marianela Verónica Carabajal, María Victoria Delpino, Gabriela Sofía Risso, et al. -
Identification and characterization of three genes encoding acyl-CoA: diacylglycerol acyltransferase (DGAT) from the microalga Myrmecia incisa Reisigl2015 / Chun-Xiu Chen, Zheng Sun, Hai-Sheng Cao, Feng-Li Fang, Long-Ling Ouyang, et al.
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Exome sequencing identifies frequent mutation of MLL2 in non–small cell lung carcinoma from Chinese patients2014 / Shanye Yin, Jing Yang, Bin Lin, Wenjun Deng, Yuchao Zhang, et al.
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Comparative ICE Genomics: Insights into the Evolution of the SXT/R391 Family of ICEs2009 / Rachel A. F. Wozniak, Derrick E. Fouts, Matteo Spagnoletti, Mauro M. Colombo, Daniela Ceccarelli, et al.
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Advanced Pre-Clinical Research Approaches and Models to Studying Pediatric Anesthetic Neurotoxicity2012 / Cheng Wang
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Evaluation of mutagenicity and metabolism-mediated cytotoxicity of the naphthoquinone 5-methoxy-3,4-dehydroxanthomegnin from Paepalanthus latipes2015 / Rodrigo R. Kitagawa, Wagner Vilegas, Eliana A. Varanda, Maria S.G. Raddi
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Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site
Summary Previous efforts to identify cross-neutralizing antibodies to the receptor-binding site (RBS) of ebolavirus glycoproteins have been unsuccessful, largely because the RBS is occluded on the viral surface. We report a monoclonal antibody...
2016 / Katie A. Howell, Xiangguo Qiu, Jennifer M. Brannan, Christopher Bryan, Edgar Davidson, et al. -
Local immunity by tissue-resident CD8+ memory T cells2012 / Thomas Gebhardt, Laura K. Mackay
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Dataset for the quantitative proteomics analysis of the primary hepatocellular carcinoma with single and multiple lesions
Abstract Hepatocellular Carcinoma (HCC) is one of the most common malignant tumor, which is causing the second leading cancer-related death worldwide. The tumor tissues and the adjacent noncancerous tissues obtained from HCC patients with single and ...
2015 / Xiaohua Xing, Yao Huang, Sen Wang, Minhui Chi, Yongyi Zeng, et al. -
Social Organization of Crop Genetic Diversity. The G × E × S Interaction Model2011 / Christian Leclerc, Geo Coppens d’Eeckenbrugge
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When Proteomics Reveals Unsuspected Roles: The Plastoglobule Example2013 / Houda Nacir, Claire Bréhélin
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The Role of the Hippo Pathway in Melanocytes and Melanoma2013 / Ji Eun Kim, Graeme J. Finlay, Bruce C. Baguley