Biological sciences topic list of research papers
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Streptomyces lunalinharesii 235 prevents the formation of a sulfate-reducing bacterial biofilm2016 / Juliana Pacheco da Rosa, Samyra Raquel Gonçalves Tibúrcio, Joana Montezano Marques, Lucy Seldin, Rosalie Reed Rodrigues Coelho
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Clust&See: A Cytoscape plugin for the identification, visualization and manipulation of network clusters
Abstract Background and scope Large networks, such as protein interaction networks, are extremely difficult to analyze as a whole. We developed Clust&See, a Cytoscape plugin dedicated to the identification, visualization and...
2013 / Lionel Spinelli, Philippe Gambette, Charles E. Chapple, Benoît Robisson, Anaïs Baudot, et al. -
Chaperone-mediated native folding of a β-scorpion toxin in the periplasm of Escherichia coli
Abstract Background Animal neurotoxin peptides are valuable probes for investigating ion channel structure/function relationships and represent lead compounds for novel therapeutics and insecticides. However, misfolding and...
2013 / A.O. O'Reilly, A.R. Cole, J.L.S. Lopes, A. Lampert, B.A. Wallace -
Large scale production of the active human ASCT2 (SLC1A5) transporter in Pichia pastoris — functional and kinetic asymmetry revealed in proteoliposomes
Abstract The human glutamine/neutral amino acid transporter ASCT2 (hASCT2) was over-expressed in Pichia pastoris and purified by Ni2+-chelating and gel filtration chromatography. The purified protein was reconstituted in liposomes by detergent...
2013 / Piero Pingitore, Lorena Pochini, Mariafrancesca Scalise, Michele Galluccio, Kristina Hedfalk, et al. -
Pre-vaccination seroprevalence of 15 human papillomavirus (HPV) types among women in the population-based Slovenian cervical screening program
Abstract Objectives To estimate seroprevalence of 11 high-risk (hr) HPV types and four low-risk (lr) HPV types among 20–64 years old Slovenian women participating in the population-based cervical cancer screening program. ...
2013 / Veronika Učakar, Mateja M. Jelen, Helena Faust, Mario Poljak, Joakim Dillner, et al. -
FSH regulates fat accumulation and redistribution in aging through the Gαi/Ca 2+ /CREB pathway2015 / Xin-Mei Liu, Hsiao Chang Chan, Guo-Lian Ding, Jie Cai, Yang Song, et al.
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Archaeogenomic insights into the adaptation of plants to the human environment: pushing plant–hominin co-evolution back to the Pliocene
Abstract The colonization of the human environment by plants, and the consequent evolution of domesticated forms is increasingly being viewed as a co-evolutionary plant–human process that occurred over a long time period, with evidence for the...
2015 / Robin G. Allaby, Logan Kistler, Rafal M. Gutaker, Roselyn Ware, James L. Kitchen, et al. -
Natural variation of macrophyte vegetation of lowland streams at the regional level
Abstract In the present study, we present a synopsis of two macrophyte surveys of physiographic units in northwest Germany carried out over one decade. Data were used to test a set of hypotheses on macrophyte distribution at the regional level....
2014 / Gerhard Wiegleb, Wolfgang Herr, Bärbel Zander, Udo Bröring, Holger Brux, et al. -
Host-Derived CD8+ Dendritic Cells Protect Against Acute Graft-versus-Host Disease after Experimental Allogeneic Bone Marrow Transplantation
Abstract Graft-versus-host disease (GVHD) is a frequent life-threatening complication after allogeneic hematopoietic stem cell transplantation (HSCT) and induced by donor-derived T cells that become activated by host antigen-presenting cells. To...
2014 / Michael Weber, Berenice Rudolph, Pamela Stein, Nir Yogev, Markus Bosmann, et al. -
EGFR-independent autophagy induction with gefitinib and enhancement of its cytotoxic effect by targeting autophagy with clarithromycin in non-small cell lung cancer cells
Abstract Gefitinib (GEF), an inhibitor for EGFR tyrosine kinase, potently induces autophagy in non-small cell lung cancer (NSCLC) cell lines such as PC-9 cells expressing constitutively activated EGFR kinase by EGFR gene mutation as well as A549 and ...
2015 / Shohei Sugita, Kentaro Ito, Yutaro Yamashiro, Shota Moriya, Xiao-Fang Che, et al. -
Proteasome inhibition in cancer is associated with enhanced tumor targeting by the adeno-associated virus/phage
Abstract Bacteriophage (phage), which are viruses that infect bacteria only, have shown promise as vehicles for targeted cancer gene therapy, albeit with poor efficiency. Recently, we generated an improved version of phage vectors by incorporating...
2012 / Justyna M. Przystal, Eloho Umukoro, Charlotte A. Stoneham, Teerapong Yata, Kevin O’Neill, et al. -
Morphological aspects of Angiostrongylus costaricensis by light and scanning electron microscopy
Abstract Angiostrongylus costaricensis is a parasitic nematode that can cause severe gastrointestinal disease, known as abdominal angiostrongiliasis, in humans. This paper presents the characterization of first- and third-stage ...
2013 / Karina M. Rebello, Rubem F.S. Menna-Barreto, Vanessa A. Chagas-Moutinho, Ester M. Mota, Jonas Perales, et al. -
The Autism ProSAP1/Shank2 mouse model displays quantitative and structural abnormalities in ultrasonic vocalisations
Abstract Mouse ultrasonic vocalisations have been often used as a paradigm to extrapolate vocal communication defects observed in patients with autism spectrum disorders (ASD). The role of these vocalisations as well as their development, structure...
2013 / Elodie Ey, Nicolas Torquet, Anne-Marie Le Sourd, Claire S. Leblond, Tobias M. Boeckers, et al. -
Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma2013 / Johannes Raffler, Werner Römisch-Margl, Ann-Kristin Petersen, Philipp Pagel, Florian Blöchl, et al.
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A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters
Summary The BCL6 transcriptional repressor is required for the development of germinal center (GC) B cells and diffuse large B cell lymphomas (DLBCLs). Although BCL6 can recruit multiple corepressors, its transcriptional repression mechanism of...
2013 / Katerina Hatzi, Yanwen Jiang, Chuanxin Huang, Francine Garrett-Bakelman, Micah D. Gearhart, et al. -
Protein aggregation profile of the human kinome2012 / Ricardo Graña-Montes, Ricardo Sant'Anna de Oliveira, Salvador Ventura
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Epigenetic distortion to VDR transcriptional regulation in prostate cancer cells
Abstract The current study aimed to examine the gene specific mechanisms by which the actions of the vitamin D receptor (VDR) are distorted in prostate cancer. Transcriptional responses toward the VDR ligand, 1α,25(OH)2D3, were examined in...
2012 / Prashant K. Singh, Craig L. Doig, Vineet K. Dhiman, Bryan M. Turner, Dominic J. Smiraglia, et al. -
The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism
Abstract Fipronil is described as a thyroid disruptor in rat. Based on the hypothesis that this results from a perturbation of hepatic thyroid hormone metabolism, our goal was to investigate the pathways involved in fipronil-induced liver gene...
2013 / Béatrice B. Roques, Julien Leghait, Marlène Z. Lacroix, Frédéric Lasserre, Thierry Pineau, et al. -
Imaging Lymph Nodes with Nanoparticles2004 /
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Variation in APOL1 Contributes to Ancestry-Level Differences in HDLc-Kidney Function Association2012 / Amy Rebecca Bentley, Ayo P. Doumatey, Guanjie Chen, Hanxia Huang, Jie Zhou, et al.