Biological sciences topic list of research papers
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Evidence for induction of humoral and cytotoxic immune responses against devil facial tumor disease cells in Tasmanian devils (Sarcophilus harrisii) immunized with killed cell preparations
Abstract Tasmanian devils (Sarcophilus harrisii) risk extinction from a contagious cancer, devil facial tumour disease (DFTD) in which the infectious agent is the tumor cell itself. Because devils are unable to produce an immune response against the ...
2015 / A. Kreiss, G.K. Brown, C. Tovar, A.B. Lyons, G.M. Woods -
Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2010: General view of the pathogens' antibacterial susceptibility
Abstract The nationwide surveillance on antimicrobial susceptibility of bacterial respiratory pathogens from patients in Japan, was conducted by Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases and Japanese Society for...
2015 / Katsunori Yanagihara, Junichi Kadota, Nobuki Aoki, Tetsuya Matsumoto, Masaki Yoshida, et al. -
Clinical utility of PKD2 mutation testing in a polycystic kidney disease cohort attending a specialist nephrology out-patient clinic2012 / Caroline Robinson, Thomas F Hiemstra, Deborah Spencer, Sarah Waller, Laura Daboo, et al.
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The orexigenic hormone acyl-ghrelin increases adult hippocampal neurogenesis and enhances pattern separation
Summary An important link exists between intact metabolic processes and normal cognitive functioning; however, the underlying mechanisms remain unknown. There is accumulating evidence that the gut hormone ghrelin, an orexigenic peptide that is...
2014 / Brianne A. Kent, Amy L. Beynon, Amanda K.E. Hornsby, Pedro Bekinschtein, Timothy J. Bussey, et al. -
KAEA (SUDPRO), a member of the ubiquitous KEOPS/EKC protein complex, regulates the arginine catabolic pathway and the expression of several other genes in Aspergillus nidulans
Abstract The kaeAKAE1 (suDpro) gene, which was identified in Aspergillus nidulans as a suppressor of proline auxotrophic mutations, encodes the orthologue of Saccharomyces cerevisiae Kae1p, a member of the evolutionarily...
2015 / Agnieszka Dzikowska, Anna Grzelak, Joanna Gawlik, Edyta Szewczyk, Paweł Mrozek, et al. -
A functional mutation at position -155 in porcine APOE promoter affects gene expression2011 / Shixin Li, Hao Zhang, Ping Gao, Zanmou Chen, Chong Wang, et al.
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Calcium and ROS: A mutual interplay
Abstract Calcium is an important second messenger involved in intra- and extracellular signaling cascades and plays an essential role in cell life and death decisions. The Ca2+ signaling network works in many different ways to regulate cellular...
2015 / Agnes Görlach, Katharina Bertram, Sona Hudecova, Olga Krizanova -
Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation
Summary An in vivo model of antiangiogenic therapy allowed us to identify genes upregulated by bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of which are involved in fatty acid uptake. In vitro, both were...
2014 / Karim Bensaad, Elena Favaro, Caroline A. Lewis, Barrie Peck, Simon Lord, et al. -
Biochemical and Structural Studies of Conserved Maf Proteins Revealed Nucleotide Pyrophosphatases with a Preference for Modified Nucleotides
Summary Maf (for multicopy associated filamentation) proteins represent a large family of conserved proteins implicated in cell division arrest but whose biochemical activity remains unknown. Here, we show that the prokaryotic and eukaryotic Maf...
2013 / Anatoli Tchigvintsev, Dmitri Tchigvintsev, Robert Flick, Ana Popovic, Aiping Dong, et al. -
Crystallization and preliminary diffraction analysis of Wzi, a member of the capsule export and assembly pathway in Escherichia coli2010 / Simon R. Bushell, Hubing Lou, Gregor D. Wallat, Konstantinos Beis, Chris Whitfield, et al.
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Crystallization and preliminary X-ray diffraction analyses of several forms of the CfaB major subunit of enterotoxigenic Escherichia coli CFA/I fimbriae2009 / Yong-Fu Li, Steven Poole, Fatima Rasulova, Annette L. McVeigh, Stephen J. Savarino, et al.
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B cell activating factor-dependent expression of vascular endothelial growth factor in MH7A human synoviocytes stimulated with tumor necrosis factor-α
Abstract Angiogenesis in rheumatoid arthritis (RA) is one of the histological hallmarks, which is mediated by expression of vascular endothelial growth factor (VEGF) in RA synovium. VEGF expression is enhanced by TNF-α, the main pro-inflammatory...
2013 / Geun-Hee Lee, Jiyoung Lee, Jae-Wook Lee, Whan Soo Choi, Eun-Yi Moon -
Improvement in Adenoviral Gene Transfer Efficiency after Preincubation at +37°C in Vitro and in Vivo2002 / M Kossila
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In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation
Abstract Therapeutics based on short interfering RNAs (siRNAs), which act by inhibiting the expression of target transcripts, represent a novel class of potent and highly specific next-generation treatments for human skin diseases. Unfortunately,...
2014 / Vikas Hegde, Robyn P. Hickerson, Sitheswaran Nainamalai, Paul A. Campbell, Frances J.D. Smith, et al. -
Dehydration of multilamellar fatty acid membranes: Towards a computational model of the stratum corneum2014 / Christopher M. MacDermaid, Russell H. DeVane, Michael L. Klein, Giacomo Fiorin
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Issue Information2014 /
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Genetic characterization of Toxoplasma gondii from Brazilian wildlife revealed abundant new genotypes
Abstract This study aimed to isolate and genotype T. gondii from Brazilian wildlife. For this purpose, 226 samples were submitted to mice bioassay and screened by PCR based on 18S rRNA sequences. A total of 15 T. gondii isolates were obtained,...
2014 / S.N. Vitaliano, H.S. Soares, A.H.H. Minervino, A.L.Q. Santos, K. Werther, et al. -
New loci and coding variants confer risk for age-related macular degeneration in East Asians2015 / Ching-Yu Cheng, Kenji Yamashiro, Li Jia Chen, Jeeyun Ahn, Lulin Huang, et al.
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Development of multiplex serological assay for the detection of human African trypanosomiasis
Abstract Human African trypanosomiasis (HAT) is a disease caused by Kinetoplastid infection. Serological tests are useful for epidemiological surveillance. The aim of this study was to develop a multiplex serological assay for HAT to assess the...
2015 / Samson Muuo Nzou, Yoshito Fujii, Masashi Miura, Matilu Mwau, Anne Wanjiru Mwangi, et al. -
Structure of protease-cleaved Escherichia coli α-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment2015 / Cameron D. Fyfe, Rhys Grinter, Inokentijs Josts, Khedidja Mosbahi, Aleksander W. Roszak, et al.