Biological sciences topic list of research papers
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Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy2011 / Olga Gorlova, Jose-Ezequiel Martin, Blanca Rueda, Bobby P. C. Koeleman, Jun Ying, et al.
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Role of redoximiRs in fibrogenesis
Abstract Fibrosis can be defined as an excessive accumulation of extracellular matrix (ECM) components, ultimately leading to stiffness, scarring and devitalized tissue. MicroRNAs (miRNAs) are short, 19–25 nucleotides (nt), non-coding RNAs involved...
2015 / Marta Fierro-Fernández, Verónica Miguel, Santiago Lamas -
Genetic Association for Renal Traits among Participants of African Ancestry Reveals New Loci for Renal Function2011 / Ching-Ti Liu, Maija K. Garnaas, Adrienne Tin, Anna Kottgen, Nora Franceschini, et al.
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Data set for the proteomic inventory and quantitative analysis of chicken eggshell matrix proteins during the primary events of eggshell mineralization and the active growth phase of calcification
Abstract Chicken eggshell is a biomineral composed of 95% calcite calcium carbonate mineral and of 3.5% organic matrix proteins. The assembly of mineral and its structural organization is controlled by its organic matrix. In a recent study [1], we...
2015 / Pauline Marie, Valérie Labas, Aurélien Brionne, Grégoire Harichaux, Christelle Hennequet-Antier, et al. -
The protective effect of eicosapentaenoic acid-enriched phospholipids from sea cucumber Cucumaria frondosa on oxidative stress in PC12 cells and SAMP8 mice
Abstract Alzheimer’s disease (AD) is a common neurodegenerative disorders, in which oxidative stress plays an important role. The present study investigated the effect of eicosapentaenoic acid-enriched phospholipids (EPA-enriched PL) from the sea...
2013 / Feng-Juan Wu, Yong Xue, Xiao-Fang Liu, Chang-Hu Xue, Jing-Feng Wang, et al. -
qFibrosis: A fully-quantitative innovative method incorporating histological features to facilitate accurate fibrosis scoring in animal model and chronic hepatitis B patients
Background & Aims There is increasing need for accurate assessment of liver fibrosis/cirrhosis. We aimed to develop qFibrosis, a fully-automated assessment method combining quantification of histopathological architectural features, to...
2014 / Shuoyu Xu, Yan Wang, Dean C.S. Tai, Shi Wang, Chee Leong Cheng, et al. -
Insights into the molecular mechanism of glucose metabolism regulation under stress in chicken skeletal muscle tissues
Abstract As substantial progress has been achieved in modern poultry production with large-scale and intensive feeding and farming in recent years, stress becomes a vital factor affecting chicken growth, development, and production yield, especially ...
2014 / Wuyi Liu, Jingpeng Zhao -
Expression of polysialylated neural cell adhesion molecules on adult stem cells after neuronal differentiation of inner ear spiral ganglion neurons
Abstract During brain development, polysialylated (polySia) neural cell adhesion molecules (polySia–NCAMs) modulate cell–cell adhesive interactions involved in synaptogenesis, neural plasticity, myelination, and neural stem cell (NSC) proliferation...
2014 / Kyoung Ho Park, Sang Won Yeo, Frederic A. Troy -
Fire and the reproductive phenology of endangered Madagascar sclerophyllous tapia woodlands
Abstract Tapia woodland vegetation is a remnant of Madagascar sclerophyllous forest that has developed under the selective pressure of fire and is dominated by the endemic tree Uapaca bojeri (Phyllanthaceae), locally named tapia. We carried out a...
2014 / Swanni T. Alvarado, Elise Buisson, Harison Rabarison, Charlotte Rajeriarison, Chris Birkinshaw, et al. -
Distinct MEG correlates of conscious experience, perceptual reversals and stabilization during binocular rivalry
Abstract During binocular rivalry, visual perception alternates spontaneously between two different monocular images. Such perceptual reversals are slowed or halted if stimuli are presented intermittently with inter-stimulus intervals larger than...
2014 / Kristian Sandberg, Gareth Robert Barnes, Bahador Bahrami, Ryota Kanai, Morten Overgaard, et al. -
Co-expression of protein complexes in prokaryotic and eukaryotic hosts: experimental procedures, database tracking and case studies2006 / Christophe Romier, Marouane Ben Jelloul, Shira Albeck, Gretel Buchwald, Didier Busso, et al.
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The use of whole-exome sequencing to disentangle complex phenotypes2015 / Hywel J Williams, John R Hurst, Louise Ocaka, Chela James, Caroline Pao, et al.
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Spreading of amyloid-β peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance
Abstract The spreading of pathology through neuronal pathways is likely to be the cause of the progressive cognitive loss observed in Alzheimer's disease (AD) and other neurodegenerative diseases. We have recently shown the propagation of AD...
2014 / Jakob Domert, Sahana Bhima Rao, Lotta Agholme, Ann-Christin Brorsson, Jan Marcusson, et al. -
Wiskott–Aldrich Syndrome protein deficiency perturbs the homeostasis of B-cell compartment in humans
Abstract Wiskott–Aldrich Syndrome protein (WASp) regulates the cytoskeleton in hematopoietic cells and mutations in its gene cause the Wiskott–Aldrich Syndrome (WAS), a primary immunodeficiency with microthrombocytopenia, eczema and a higher...
2013 / Maria Carmina Castiello, Marita Bosticardo, Francesca Pala, Marco Catucci, Nicolas Chamberlain, et al. -
Intrinsic Resistance to MEK Inhibition in KRAS Mutant Lung and Colon Cancer through Transcriptional Induction of ERBB3
Summary There are no effective therapies for the ∼30% of human malignancies with mutant RAS oncogenes. Using a kinome-centered synthetic lethality screen, we find that suppression of the ERBB3 receptor tyrosine kinase sensitizes KRAS mutant lung and ...
2014 / Chong Sun, Sebastijan Hobor, Andrea Bertotti, Davide Zecchin, Sidong Huang, et al. -
Genotype-induced changes in biophysical properties of frontal cortex lipid raft from APP/PS1 transgenic mice2012 / Mario L. Diaz, Noemí Fabelo, Raquel Marín
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Remaining structures at the N- and C-terminal regions of alpha-synuclein accurately elucidated by amide-proton exchange NMR with fitting
Abstract Alpha-synuclein is analyzed in physiological conditions by CLEANEX-PM methodology, in which the amide-proton exchange can be monitored at millisecond scale. The relationship between k ex and [OH]− is confirmed as a...
2013 / Honoka Okazaki, Yuka Ohori, Masaya Komoto, Young-Ho Lee, Yuji Goto, et al. -
Detection of Leishmania donovani and L. tropica in Ethiopian wild rodents
Abstract Human visceral (VL, also known as Kala-azar) and cutaneous (CL) leishmaniasis are important infectious diseases affecting countries in East Africa that remain endemic in several regions of Ethiopia. The transmission and epidemiology of the...
2015 / Aysheshm Kassahun, Jovana Sadlova, Vit Dvorak, Tatiana Kostalova, Iva Rohousova, et al. -
Hyperdominance in Amazonian forest carbon cycling2015 / Sophie Fauset, Michelle O. Johnson, Manuel Gloor, Timothy R. Baker, Abel Monteagudo M., et al.
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Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts
Abstract We compared mouse embryonic stem (ES) cells and fibroblasts (MEFs) for their ability to metabolically activate the environmental carcinogens benzo[a]pyrene (BaP), 3-nitrobenzanthrone (3-NBA) and aristolochic acid I (AAI), measuring DNA...
2014 / Annette M. Krais, Karl-Rudolf Mühlbauer, Jill E. Kucab, Helena Chinbuah, Michael G. Cornelius, et al.