Biological sciences topic list of research papers
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Genetic diversity, paraphyly and incomplete lineage sorting of mtDNA, ITS2 and microsatellite flanking region in closely related Heliopora species (Octocorallia)
Abstract Examining genetic diversity and lineage sorting of different genes in closely related species provide useful information for phylogenetic analyses and ultimately for understanding the origins of biodiversity. In this study, we examined...
2015 / Nina Yasuda, Coralie Taquet, Satoshi Nagai, Miguel Fortes, Tung-Yung Fan, et al. -
Population Genomics of Mycobacterium tuberculosis in Ethiopia Contradicts the Virgin Soil Hypothesis for Human Tuberculosis in Sub-Saharan Africa
Summary Colonial medical reports claimed that tuberculosis (TB) was largely unknown in Africa prior to European contact, providing a “virgin soil” for spread of TB in highly susceptible populations previously unexposed to the disease [1, 2]. This is ...
2015 / Iñaki Comas, Elena Hailu, Teklu Kiros, Shiferaw Bekele, Wondale Mekonnen, et al. -
Reprogramming of the non-coding transcriptome during brain development2010 / Saba Valadkhan, Timothy W Nilsen
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Functional expression of TcoAT1 reveals it to be a P1-type nucleoside transporter with no capacity for diminazene uptake
Abstract It has long been established that the Trypanosoma brucei TbAT1/P2 aminopurine transporter is involved in the uptake of diamidine and arsenical drugs including pentamidine, diminazene aceturate and melarsoprol. Accordingly, it was proposed...
2013 / Jane C. Munday, Karla E. Rojas López, Anthonius A. Eze, Vincent Delespaux, Jan Van Den Abbeele, et al. -
Contribution of Global Rare Copy-Number Variants to the Risk of Sporadic Congenital Heart Disease
Previous studies have shown that copy-number variants (CNVs) contribute to the risk of complex developmental phenotypes. However, the contribution of global CNV burden to the risk of sporadic congenital heart disease (CHD) remains incompletely defined. We...
2012 / Rachel Soemedi, Ian J. Wilson, Jamie Bentham, Rebecca Darlay, Ana Töpf, et al. -
Neonatal sepsis due to multidrug-resistant Klebsiella terrigena in the neonatal intensive care unit in Gaza, Palestine2007 / Farid Elamreen
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LRIG2 Mutations Cause Urofacial Syndrome
Urofacial syndrome (UFS) (or Ochoa syndrome) is an autosomal-recessive disease characterized by congenital urinary bladder dysfunction, associated with a significant risk of kidney failure, and an abnormal facial expression upon smiling, laughing, and crying. We...
2013 / Helen M. Stuart, Neil A. Roberts, Berk Burgu, Sarah B. Daly, Jill E. Urquhart, et al. -
Endocytosis and intracellular processing of BODIPY-sphingomyelin by murine CATH.a neurons
Abstract Neuronal sphingolipids (SL) play important roles during axonal extension, neurotrophic receptor signaling and neurotransmitter release. Many of these signaling pathways depend on the presence of specialized membrane microdomains termed...
2013 / Christoph Nusshold, Andreas Uellen, Eva Bernhart, Astrid Hammer, Sabine Damm, et al. -
A new species of Aguna Williams (Lepidoptera, Hesperiidae) from Panamá belonging to the “claxon group”2015 / Ricardo Russo Siewert, Gabriela Lourenço Leviski, Olaf Hermann Hendrik Mielke, Mirna Martins Casagrande
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Habitat models of wood-inhabiting fungi along a decay gradient of Norway spruce logs
Abstract Information on the habitat requirements of wood-inhabiting fungi is needed to understand the factors that affect their diversity. We applied culture-free DNA extraction and 454-pyrosequencing to study the mycobiota of decaying Norway spruce ...
2015 / Tiina Rajala, Tero Tuomivirta, Taina Pennanen, Raisa Mäkipää -
Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names2014 / Jens Kuhn, Kristian Andersen, Yīmíng Bào, Sina Bavari, Stephan Becker, et al.
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Radiosensitizing effect of PSMC5, a 19S proteasome ATPase, in H460 lung cancer cells
Abstract The function of PSMC5 (proteasome 26S subunit, ATPase 5) in tumors, particularly with respect to cancer radioresistance, is not known. Here, we identified PSMC5 as a novel radiosensitivity biomarker, demonstrating that radiosensitive H460...
2015 / Ji-Hye Yim, Hong Shik Yun, Su-Jae Lee, Jeong-Hwa Baek, Chang-Woo Lee, et al. -
Oncogenic Properties of Apoptotic Tumor Cells in Aggressive B Cell Lymphoma
Summary Background Cells undergoing apoptosis are known to modulate their tissue microenvironments. By acting on phagocytes, notably macrophages, apoptotic cells inhibit immunological and inflammatory responses and promote trophic...
2015 / Catriona A. Ford, Sofia Petrova, John D. Pound, Jorine J.L.P. Voss, Lynsey Melville, et al. -
Using synchrotrons and XFELs for time-resolved X-ray crystallography and solution scattering experiments on biomolecules
Time-resolved structural information is key to understand the mechanism of biological processes, such as catalysis and signalling. Recent developments in X-ray sources as well as data collection and analysis methods are making routine time-resolved X-ray...
2015 / Matteo Levantino, Briony A Yorke, Diana CF Monteiro, Marco Cammarata, Arwen R Pearson -
The transcriptional landscape of age in human peripheral blood2015 / Marjolein J. Peters, Roby Joehanes, Luke C. Pilling, Claudia Schurmann, Karen N. Conneely, et al.
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Membrane protein structural biology using X-ray free electron lasers
Membrane protein structural biology has benefitted tremendously from access to micro-focus crystallography at synchrotron radiation sources. X-ray free electron lasers (XFELs) are linear accelerator driven X-ray sources that deliver a jump in peak X-ray brilliance ...
2015 / Richard Neutze, Gisela Brändén, Gebhard FX Schertler -
Graphical tools for macromolecular crystallography in PHENIX2012 / Nathaniel Echols, Ralf W. Grosse-Kunstleve, Pavel V. Afonine, Gábor Bunkóczi, Vincent B. Chen, et al.
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Contraction-stimulated glucose transport in muscle is controlled by AMPK and mechanical stress but not sarcoplasmatic reticulum Ca2+ release
Abstract Understanding how muscle contraction orchestrates insulin-independent muscle glucose transport may enable development of hyperglycemia-treating drugs. The prevailing concept implicates Ca2+ as a key feed forward regulator of glucose...
2014 / Thomas E. Jensen, Lykke Sylow, Adam J. Rose, Agnete B. Madsen, Yeliz Angin, et al. -
GWAS-based pathway analysis differentiates between fluid and crystallized intelligence2014 / A. Christoforou, T. Espeseth, G. Davies, C. P. D. Fernandes, S. Giddaluru, et al.
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Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis
Abstract We recently reported that young (3 to 4months old) mice lacking Exon 1 of the Smad7 gene (S7ΔEx1 mice) show enhanced proliferation of neural stem and progenitor cells (NPCs) in the hippocampal dentate gyrus (DG) and in the subventricular...
2014 / Julia Marschallinger, Monika Krampert, Sebastien Couillard-Despres, Rainer Heuchel, Ulrich Bogdahn, et al.