Chemical sciences topic list of research papers
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Preclinical pharmacokinetics, biodistribution, radiation dosimetry and toxicity studies required for regulatory approval of a phase I clinical trial with 111In-CP04 in medullary thyroid carcinoma patients
Abstract Introduction From a series of radiolabelled cholecystokinin (CCK) and gastrin analogues, 111In-CP04 (111In-DOTA-(DGlu)6-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2) was selected for further translation as a diagnostic...
2016 / Theodosia Maina, Mark W. Konijnenberg, Petra KolencPeitl, Piotr Garnuszek, Berthold A. Nock, et al. -
Using exomarkers to assess mitochondrial reactive species in vivo
Abstract Background The ability to measure the concentrations of small damaging and signalling molecules such as reactive oxygen species (ROS) in vivo is essential to understanding their biological roles. While a range of methods...
2013 / Angela Logan, Helena M. Cochemé, Pamela Boon Li Pun, Nadezda Apostolova, Robin A.J. Smith, et al. -
ZYTOLOGISCHE STUDIEN AN MONOSOMISCHEN TYPEN VON GODETIA WHITNEYI2010 / ARTUR HÄKANSSON
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Combinatorial Chemistry Online2012 / N.K. Terrett
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Reactivity enhancement of oxide skins in reversible Ti-doped NaAlH42014 / Renaud Delmelle, Jeffrey C. Gehrig, Andreas Borgschulte, Andreas Züttel
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Optimization of metabolite extraction of human vein tissue for ultra performance liquid chromatography-mass spectrometry and nuclear magnetic resonance-based untargeted metabolic profiling2015 / Muzaffar A. Anwar, Panagiotis A. Vorkas, Jia V. Li, Joseph Shalhoub, Elizabeth J. Want, et al.
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Demonstration of equivalence of a generic glatiramer acetate (Glatopa™)
Abstract Glatiramer acetate (GA) has been available under the brand name Copaxone® for nearly two decades. Recently, the US Food and Drug Administration (FDA) approved the first generic GA, Glatopa™, as fully substitutable for all indications for...
2015 / James Anderson, Christine Bell, John Bishop, Ishan Capila, Tanmoy Ganguly, et al. -
Pyridinium 5-[(1,3-diethyl-6-hydroxy-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(2-methoxyphenyl)methyl]-1,3-diethyl-4,6-dioxo-2-thioxopyrimidin-5-ide2009 / Abdullah Mohamed Asiri, Salman A. Khan, Seik Weng Ng
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Hierarchical cobalt-formate framework series with (412⋅63)(49⋅66)n (n = 1–3) topologies exhibiting slow dielectric relaxation and weak ferromagnetism2014 / Ran Shang, Sa Chen, Ke-Li Hu, Ze-Chun Jiang, Bing-Wu Wang, et al.
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Discovery of a novel (R)-selective bacterial hydroxynitrile lyase from Acidobacterium capsulatum
Abstract Hydroxynitrile lyases (HNLs) are powerful carbon–carbon bond forming enzymes. The reverse of their natural reaction – the stereoselective addition of hydrogen cyanide (HCN) to carbonyls – yields chiral cyanohydrins, versatile building...
2014 / Romana Wiedner, Mandana Gruber-Khadjawi, Helmut Schwab, Kerstin Steiner -
Antioxidant, inhibition of α-glucosidase and suppression of nitric oxide production in LPS-induced murine macrophages by different fractions of Actinidia arguta stem
Abstract In traditional systems of medicine, fruits, leaves, and stems of Actinidia arguta (Sieb. et Zucc.) Planch. ex Miq. have been used to treat various inflammatory diseases. The present study determined the proximate composition, antioxidant,...
2014 / Jaehak Lee, Kandhasamy Sowndhararajan, Mihae Kim, Jaehun Kim, Daeho Kim, et al. -
Arene ruthenium dithiolato–carborane complexes for boron neutron capture therapy (BNCT)
Abstract We report the effect of low-energy thermal neutron irradiation on the antiproliferative activities of a highly hydrophobic organometallic arene ruthenium dithiolato–carborane complex [Ru(p-cymene)...
2015 / Isolda Romero-Canelón, Ben Phoenix, Anaïs Pitto-Barry, Johanna Tran, Joan J. Soldevila-Barreda, et al. -
Discovery and resupply of pharmacologically active plant-derived natural products: A review
Abstract Medicinal plants have historically proven their value as a source of molecules with therapeutic potential, and nowadays still represent an important pool for the identification of novel drug leads. In the past decades, pharmaceutical...
2015 / Atanas G. Atanasov, Birgit Waltenberger, Eva-Maria Pferschy-Wenzig, Thomas Linder, Christoph Wawrosch, et al. -
On the Mechanism of Cuprate Crystal Growth: The Role of Mixed Metal Carbonates2015 / David C. Green, Rebecca Boston, Stefan Glatzel, Martin R. Lees, Stuart C. Wimbush, et al.
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The stability of microbially reduced U(IV); impact of residual electron donor and sediment ageing
Abstract The stimulation of microbial U(VI) reduction to precipitate insoluble U(IV) has been proposed as a means of remediating mobile uranium groundwater contamination. Crucial to the success of such a remediation strategy is determining the...
2015 / Laura Newsome, Katherine Morris, Samuel Shaw, Divyesh Trivedi, Jonathan R. Lloyd -
Parallel synthesis of novel benzimidazoles on a soluble polymer support2006 / Ling-Ju Chang, Manohar Kulkarni, Chung-Ming Sun
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Stability-Indicating RP-HPLC Method for Determination of Ambrisentan and Tadalafil in Pharmaceutical Dosage Form2014 / Jayvadan K. Patel
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Singlet Oxygen in Antimicrobial Photodynamic Therapy: Photosensitizer-Dependent Production and Decay in E. coli2013 / Xavier Ragàs, Xin He, Montserrat Agut, Mónica Roxo-Rosa, António Gonsalves, et al.
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Hydrothermal synthesis of Eu3+ doped yttria nanoparticles using a supercritical flow reaction system
Abstract Highly crystalline Eu3+ doped yttria nanoparticle was synthesized by hydrothermal reaction in supercritical water using a continuous flow reaction system (FHT). The reactants of Y(NO3)3/Eu(NO3)3 mixed solution and KOH solution were used as...
2012 / Hiromichi Hayashi -
Fiber Optic Coupled Raman Based Detection of Hazardous Liquids Concealed in Commercial Products2012 / Michael L. Ramírez-Cedeño, Natalie Gaensbauer, Hilsamar Félix-Rivera, William Ortiz-Rivera, Leonardo Pacheco-Londoño, et al.