Chemical sciences topic list of research papers
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A microfluidic device for the hydrodynamic immobilisation of living fission yeast cells for super-resolution imaging
Abstract We describe a microfluidic device designed specifically for the reversible immobilisation of Schizosaccharomyces pombe (Fission Yeast) cells to facilitate live cell super-resolution microscopy. Photo-Activation Localisation Microscopy...
2013 / Laurence Bell, Ashwin Seshia, David Lando, Ernest Laue, Matthieu Palayret, et al. -
Structural analysis of highly porous γ-Al2O3
Abstract Two highly porous γ-aluminas, a commercial catalyst obtained from the calcination of boehmite and a highly mesoporous product obtained from amorphous aluminum (oxy)hydroxide via a sol–gel-based process were investigated by 27Al nuclear...
2014 / Louise Samain, Aleksander Jaworski, Mattias Edén, Danielle M. Ladd, Dong-Kyun Seo, et al. -
Oral effectiveness of PMIC4, a novel hydroxyethylpiperazine analogue, in Leishmania amazonensis
Abstract Pentavalent antimonials have saved the lives of thousands of Leishmania-infected patients more than seventy years but, unfortunately, they are highly toxic and require parenteral delivery. Therefore, the search for safer and orally...
2014 / Mariela Ferreira de Vasconcelos, Edézio Ferreira da Cunha-Júnior, Valter Viana de Andrade-Neto, Larissa Moreira Siqueira, Cláudia Masini d’Avila-Levy, et al. -
Cellulose nanoparticles are a biodegradable photoacoustic contrast agent for use in living mice
Abstract Molecular imaging with photoacoustic ultrasound is an emerging field that combines the spatial and temporal resolution of ultrasound with the contrast of optical imaging. However, there are few imaging agents that offer both high signal...
2014 / Jesse V. Jokerst, Dominique Van de Sompel, Sarah E. Bohndiek, Sanjiv S. Gambhir -
Agaricus meleagris pyranose dehydrogenase: Influence of covalent FAD linkage on catalysis and stability
Abstract Pyranose dehydrogenase (PDH) is a monomeric flavoprotein belonging to the glucose–methanol–choline (GMC) family of oxidoreductases. It catalyzes the oxidation of free, non-phosphorylated sugars to the corresponding keto sugars. The enzyme...
2014 / Iris Krondorfer, Dagmar Brugger, Regina Paukner, Stefan Scheiblbrandner, Katharina F. Pirker, et al. -
Multidrug resistance–reversal effects of resin glycosides from Dichondra repens
Abstract Investigation of hydrophobic extract of Dichondra repens (Convolvulaceae) led to the isolation of three new resin glycosides dichondrins A–C (1–3), and three known resin glycosides cus-1, cus-2, and cuse 3. All the isolated resin glycosides ...
2015 / Wei-bin Song, Wen-qiong Wang, Shu-wei Zhang, Li-jiang Xuan -
Utility of recombinant fragment C for assessment of anti-tetanus antibodies in plasma
Abstract Anti-tetanus antibodies in biological samples are typically detected using an enzyme-linked immunosorbent assay based on toxoided tetanus neurotoxin as antigen. We demonstrate that recombinantly produced fragment C of the toxin heavy chain...
2015 / Girija Ramakrishnan, Karl Pedersen, Denis Guenette, Joyce Sink, Rashidul Haque, et al. -
Inorganic Phosphorus and Potassium Are Putative Indicators of Delayed Separation of Whole Blood
Abstract Objectives The delayed separation of whole blood can influence the concentrations of circulating blood components, including metabolites and cytokines. The aim of this study was to determine whether clinical-biochemistry...
2015 / Jae-Eun Lee, Maria Hong, Seul-Ki Park, Ji-In Yu, Jin-Sook Wang, et al. -
Bioresource utilisation by sustainable technologies in new value-added biorefinery concepts – two case studies from food and forest industry
Abstract This paper presents a trans-disciplinary assessment of new and innovative biorefinery concepts producing high-value chemical compounds from residues from agriculture, food and forest industries. There is a significant potential of biomass...
2013 / Anna Ekman, Monica Campos, Sofia Lindahl, Michelle Co, Pål Börjesson, et al. -
Feasibility study of calibration strategy for direct quantitative measurement of K and Mg in plant material by laser-induced breakdown spectrometry
Abstract The calibration and quantitative measurement is the “Achilles heel” of the LIBS technique. This paper deals with a method developed for the direct measurement of K and Mg in plant samples. Instrumental parameters were optimized and the best ...
2015 / Daniel Menezes Silvestre, Felipe Miranda Barbosa, Bruno Teves Aguiar, Flávio Oliveira Leme, Cassiana Seimi Nomura -
Phosphotyrosine profiling identifies ephrin receptor A2 as a potential therapeutic target in esophageal squamous-cell carcinoma2014 / Nazia Syed, Mustafa A. Barbhuiya, Sneha M. Pinto, Raja Sekhar Nirujogi, Santosh Renuse, et al.
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Effects of Three Commonly-used Diuretics on the Urinary Proteome
Abstract Biomarker is the measurable change associated with a physiological or pathophysiological process. Unlike blood which has mechanisms to keep the internal environment homeostatic, urine is more likely to reflect changes of the body. As a...
2014 / Xundou Li, Mindi Zhao, Menglin Li, Lulu Jia, Youhe Gao -
An azide functionalized oligothiophene ligand – A versatile tool for multimodal detection of disease associated protein aggregates
Abstract Ligands for identifying protein aggregates are of great interest as such deposits are the pathological hallmark of a wide range of severe diseases including Alzheimer's and Parkinson's disease. Here we report the synthesis of an azide...
2014 / Leif B.G. Johansson, Rozalyn Simon, Gunnar Bergström, Mikaela Eriksson, Stefan Prokop, et al. -
Identification of GNE-293, a potent and selective PI3Kδ inhibitor: Navigating in vitro genotoxicity while improving potency and selectivity
Abstract In an effort to identify potent and isoform selective inhibitors of PI3Kδ, GNE-293 (34) was identified. Inhibitor 2 was found to induce micronuclei formation in both the MNT and HCA in vitro assays. Compounds testing negative for...
2013 / Brian S. Safina, Zachary K. Sweeney, Jun Li, Bryan K. Chan, Angelina Bisconte, et al. -
A double bond-conjugated dimethylnitrobenzene-type photolabile nitric oxide donor with improved two-photon cross section
Abstract Photocontrollable NO donors enable precise spatiotemporal release of NO under physiological conditions. We designed and synthesized a novel dimethylnitrobenzene-type NO donor, Flu-DNB-DB, which contains a carbon–carbon double bond in place...
2015 / Naoya Ieda, Kazuhiro Hishikawa, Kei Eto, Kai Kitamura, Mitsuyasu Kawaguchi, et al. -
Local structure of alkalis in mixed-alkali borate glass to elucidate the origin of mixed-alkali effect
Abstract We report the structural analysis of Na+ and Cs+ in sodium cesium borate crystals and glasses using 23Na and 133Cs magic-angle spinning nuclear magnetic resonance (MAS NMR) spectroscopy. The composition dependence of NMR spectra of the...
2015 / Yomei Tokuda, Yuya Takahashi, Hirokazu Masai, Shunichi Kaneko, Yoshikatsu Ueda, et al. -
Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy
Abstract Two new oxanthrone C-glycosides, patientosides A (14) and B (15), together with three known ones (11–13), were isolated from Rumex patientia. Their structures were identified on the basis of spectroscopic methods. The absolute configuration ...
2013 / Yang Yang, Yong-Ming Yan, Wei Wei, Jie Luo, Lan-Sheng Zhang, et al. -
New editorial board members2002 /
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Targeting histone lysine demethylases — Progress, challenges, and the future
Abstract N-Methylation of lysine and arginine residues has emerged as a major mechanism of transcriptional regulation in eukaryotes. In humans, N ε-methyllysine residue demethylation is catalysed by two...
2014 / Cyrille C. Thinnes, Katherine S. England, Akane Kawamura, Rasheduzzaman Chowdhury, Christopher J. Schofield, et al. -
2-(1,3-Benzothiazol-2-ylsulfanyl)-1-phenylethanone2009 / Hossein Loghmani-Khouzani, Dariush Hajiheidari, Ward T. Robinson, Noorsaadah Abdul Rahman, Reza Kia