Biological sciences topic list of research papers
-
Complete genome sequence of Cellulomonas flavigena type strain (134T)2010 / Birte Abt, Brian Foster, Alla Lapidus, Alicia Clum, Hui Sun, et al.
-
Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential
Summary Reports on the retention of somatic cell memory in induced pluripotent stem cells (iPSCs) have complicated the selection of the optimal cell type for the generation of iPSC biobanks. To address this issue we compared transcriptomic,...
2016 / Aija Kyttälä, Roksana Moraghebi, Cristina Valensisi, Johannes Kettunen, Colin Andrus, et al. -
Congenital Nystagmus Gene FRMD7 Is Necessary for Establishing a Neuronal Circuit Asymmetry for Direction Selectivity
Summary Neuronal circuit asymmetries are important components of brain circuits, but the molecular pathways leading to their establishment remain unknown. Here we found that the mutation of FRMD7, a gene that is defective in human congenital...
2015 / Keisuke Yonehara, Michele Fiscella, Antonia Drinnenberg, Federico Esposti, Stuart Trenholm, et al. -
Influenza A(H1N1)pdm09 and postpandemic influenza in Lithuania2016 / Arvydas Ambrozaitis, Daiva Radzišauskienė, Kęstutis Žagminas, Nerija Kuprevičienė, Stefan Gravenstein, et al.
-
Adjustments of molecular key components of branchial ion and pH regulation in Atlantic cod (Gadus morhua) in response to ocean acidification and warming
Abstract Marine teleost fish sustain compensation of extracellular pH after exposure to hypercapnia by means of efficient ion and acid–base regulation. Elevated rates of ion and acid–base regulation under hypercapnia may be stimulated further by...
2015 / Katharina Michael, Cornelia M. Kreiss, Marian Y. Hu, Nils Koschnick, Ulf Bickmeyer, et al. -
Mouse model for inherited renal fibrosis associated with endoplasmic reticulum stress2017 / Sian E. Piret, Eric Olinger, Anita A. C. Reed, M. Andrew Nesbit, Tertius A. Hough, et al.
-
Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1
Abstract Background Familial Cerebral Cavernous Malformation type 1 (CCM1) is an autosomal dominant disease caused by mutations in the Krev Interaction Trapped 1 (KRIT1/CCM1) gene, and characterized by multiple brain lesions. CCM...
2016 / Hélène Choquet, Eliana Trapani, Luca Goitre, Lorenza Trabalzini, Amy Akers, et al. -
Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection
Summary Individual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1) infection have been of interest for decades. We aimed to determine the contribution of large isoform of Mammalian DnaJ (MRJ-L), a HIV-1 Vpr-interacting...
2014 / Yu-Ping Chiang, Wang-Huei Sheng, Pei-Lan Shao, Ya-Hui Chi, Yi-Ming Arthur Chen, et al. -
Data supporting the role of enzymes and polysaccharides during cassava postharvest physiological deterioration
Abstract This data article is referred to the research article entitled The role of ascorbate peroxidase, guaiacol peroxidase, and polysaccharides in cassava (Manihot esculenta Crantz) roots under postharvest physiological deterioration by Uarrota...
2016 / Virgílio Gavicho Uarrota, Rodolfo Moresco, Eder Carlos Schmidt, Zenilda Laurita Bouzon, Eduardo da Costa Nunes, et al. -
Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids2016 / Mathew H. Horrocks, Steven F. Lee, Sonia Gandhi, Nadia K. Magdalinou, Serene W. Chen, et al.
-
Designer lignins: harnessing the plasticity of lignification
Lignin is a complex polyphenolic constituent of plant secondary cell walls. Inspired largely by the recalcitrance of lignin to biomass processing, plant engineering efforts have routinely sought to alter lignin quantity, composition, and structure by exploiting...
2016 / Yaseen Mottiar, Ruben Vanholme, Wout Boerjan, John Ralph, Shawn D Mansfield -
Genetic loci for serum lipid fractions and intracerebral hemorrhage
Abstract Background Serum total cholesterol and its fractions are inversely associated with intracerebral hemorrhages (ICH) and their potential subclinical precursor, cerebral microbleeds. To ascertain whether there is a genetic...
2016 / Saloua Akoudad, M. Arfan Ikram, Marileen L.P. Portegies, Hieab H. Adams, Daniel Bos, et al. -
A genetical approach to deep venous thrombosis2012 / Celal Yavuz
-
Implications of multiple freeze-thawing on respiratory samples for culture-independent analyses
Abstract Background Best practice when performing culture-independent microbiological analysis of sputum samples involves their rapid freezing and storage at −80°C. However, accessing biobanked collections can mean that material...
2014 / Leah Cuthbertson, Geraint B. Rogers, Alan W. Walker, Anna Oliver, Lucas R. Hoffman, et al. -
Mesenchymal Stem Cells Shed Amphiregulin at the Surface of Lung Carcinoma Cells in a Juxtacrine Manner
Abstract Solid tumors comprise cancer cells and different supportive stromal cells, including mesenchymal stem cells (MSCs), which have recently been shown to enhance tumor growth and metastasis. We provide new mechanistic insights into how bone...
2015 / Oriane Carnet, Julie Lecomte, Anne Masset, Irina Primac, Tania Durré, et al. -
Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis
Summary The proneural transcription factor Ascl1 coordinates gene expression in both proliferating and differentiating progenitors along the neuronal lineage. Here, we used a cellular model of neurogenesis to investigate how Ascl1 interacts with the ...
2015 / Alexandre A.S.F. Raposo, Francisca F. Vasconcelos, Daniela Drechsel, Corentine Marie, Caroline Johnston, et al. -
Easy mammalian expression and crystallography of maltose-binding protein-fused human proteins
Abstract We present a strategy to obtain milligrams of highly post-translationally modified eukaryotic proteins, transiently expressed in mammalian cells as rigid or cleavable fusions with a mammalianized version of bacterial maltose-binding protein ...
2016 / Marcel Bokhove, Hamed Sadat Al Hosseini, Takako Saito, Elisa Dioguardi, Katharina Gegenschatz-Schmid, et al. -
The 11S Proteasome Subunit PSME3 Is a Positive Feedforward Regulator of NF-κB and Important for Host Defense against Bacterial Pathogens
Summary The NF-κB pathway plays important roles in immune responses. Although its regulation has been extensively studied, here, we report an unknown feedforward mechanism for the regulation of this pathway by Toll-like receptor (TLR) ligands in...
2016 / Jinxia Sun, Yi Luan, Dong Xiang, Xiao Tan, Hui Chen, et al. -
Combined use of empirical data and mathematical modelling to better estimate the microbial turnover of isotopically labelled carbon substrates in soil
Abstract The flow of carbon (C) through soil is inherently complex due to the many thousands of different chemical transformations occurring simultaneously within the soil microbial community. The accurate modelling of this C flow therefore...
2015 / H.C. Glanville, P.W. Hill, A. Schnepf, E. Oburger, D.L. Jones -
Complete metagenome sequencing based bacterial diversity and functional insights from basaltic hot spring of Unkeshwar, Maharashtra, India
Abstract Unkeshwar hot springs are located at geographical South East Deccan Continental basalt of India. Here, we report the microbial community analysis of this hot spring using whole metagenome shotgun sequencing approach. The analysis revealed a ...
2015 / Gajanan T. Mehetre, Aditi S. Paranjpe, Syed G. Dastager, Mahesh S. Dharne