Biological sciences topic list of research papers
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Plasma Membrane-Targeted PIN Proteins Drive Shoot Development in a Moss
Summary Background Plant body plans arise by the activity of meristematic growing tips during development and radiated independently in the gametophyte (n) and sporophyte (2n) stages of the life cycle during evolution. Although...
2014 / Tom A. Bennett, Maureen M. Liu, Tsuyoshi Aoyama, Nicole M. Bierfreund, Marion Braun, et al. -
Generation of Highly Cytotoxic Natural Killer Cells for Treatment of Acute Myelogenous Leukemia Using a Feeder-Free, Particle-Based Approach
Abstract Natural killer (NK) cell immunotherapy as a cancer treatment shows promise, but expanding NK cells consistently from a small fraction (∼5%) of peripheral blood mononuclear cells (PBMCs) to therapeutic amounts remains challenging. Most...
2015 / Jeremiah L. Oyer, Robert Y. Igarashi, Alexander R. Kulikowski, Dominic A. Colosimo, Melhem M. Solh, et al. -
Comprehensive assessment of expression of insulin signaling pathway components in subcutaneous adipose tissue of women with and without polycystic ovary syndrome
Abstract Objective Insulin resistance is a common feature of polycystic ovary syndrome (PCOS). The insulin signaling pathway consists of two major pathways, the metabolic and the mitogenic cascades. The many components of these...
2015 / Ning Xu, David H. Geller, Michelle R. Jones, Vincent A. Funari, Ricardo Azziz, et al. -
Krüppel-like transcription factor 8 (Klf8) is expressed and active in the neurons of the mouse brain
Abstract Krüppel-like transcription factor 8 (KLF8) is a transcription factor suggested to be involved in various cellular events, including malignant cell transformation, still its expression in the adult rodent brain remained unknown. To analyze...
2015 / Marina Dobrivojević, Nikola Habek, Katarina Kapuralin, Marija Ćurlin, Srećko Gajović -
Protective properties of lysozyme on β-amyloid pathology: implications for Alzheimer disease
Abstract The hallmarks of Alzheimer disease are amyloid-β plaques and neurofibrillary tangles accompanied by signs of neuroinflammation. Lysozyme is a major player in the innate immune system and has recently been shown to prevent the aggregation of ...
2015 / Linda Helmfors, Andrea Boman, Livia Civitelli, Sangeeta Nath, Linnea Sandin, et al. -
Improvement of diaphragmatic performance through orthotopic application of decellularized extracellular matrix patch
Abstract Muscle tissue engineering can provide support to large congenital skeletal muscle defects using scaffolds able to allow cell migration, proliferation and differentiation. Acellular extracellular matrix (ECM) scaffold can generate a positive ...
2015 / M. Piccoli, L. Urbani, M.E. Alvarez-Fallas, C. Franzin, A. Dedja, et al. -
The effect of antibiotic exposure on eicosanoid generation from arachidonic acid and gene expression in a primitive chordate, Branchiostoma belcheri
Abstract Chloramphenicol (Chl) is an effective antimicrobial agent widely used in veterinary medicine and commonly used in fish. Its use is restricted in the clinic because of adverse effects on the immune system and oxidative stress in mammals....
2015 / Dongjuan Yuan, Minming Pan, Qiuqiong Zou, Chengyong Chen, Shangwu Chen, et al. -
Data for the characterization of the HSP70 family during osmotic stress in banana, a non-model crop
Abstract Here, we present the data from an in-depth analysis of the HSP70 family in the non-model banana during osmotic stress [1]. First, a manual curation of HSP70 sequences from the banana genome was performed and updated on the Musa hub...
2015 / Anne-Catherine Vanhove, Wesley Vermaelen, Alberto Cenci, Rony Swennen, Sebastien C. Carpentier -
Genome sequencing of herb Tulsi (Ocimum tenuiflorum) unravels key genes behind its strong medicinal properties2015 / Atul K. Upadhyay, Anita R. Chacko, A. Gandhimathi, Pritha Ghosh, K. Harini, et al.
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DNA microarray analysis of the cyanotroph Pseudomonas pseudoalcaligenes CECT5344 in response to nitrogen starvation, cyanide and a jewelry wastewater
Abstract Pseudomonas pseudoalcaligenes CECT5344 is an alkaliphilic bacterium that can use cyanide as nitrogen source for growth, becoming a suitable candidate to be applied in biological treatment of cyanide-containing...
2015 / V.M. Luque-Almagro, M.P. Escribano, I. Manso, L.P. Sáez, P. Cabello, et al. -
Annual trend patterns of phytoplankton species abundance belie homogeneous taxonomical group responses to climate in the NE Atlantic upwelling
Abstract Phytoplankton is a sentinel of marine ecosystem change. Composed by many species with different life-history strategies, it rapidly responds to environment changes. An analysis of the abundance of 54 phytoplankton species in Galicia (NW...
2015 / Antonio Bode, M. Graciela Estévez, Manuel Varela, José A. Vilar -
Plant species’ origin predicts dominance and response to nutrient enrichment and herbivores in global grasslands2015 / Eric W. Seabloom, Elizabeth T. Borer, Yvonne M. Buckley, Elsa E. Cleland, Kendi F. Davies, et al.
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cis -Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer Independent
Summary Alterations in distal regulatory elements that control gene expression underlie many diseases, including cancer. Epigenomic analyses of normal and diseased cells have produced correlative predictions for connections between dysregulated...
2017 / Yue Huang, Olivia I. Koues, Jiang-yang Zhao, Regina Liu, Sarah C. Pyfrom, et al. -
A New Paradigm for an Old Story: The Role of Regulatory B Cells in Cancer2012 / Arya Biragyn, Catalina Lee-Chang
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Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point
Summary Recurrent mutations in the spliceosome are observed in several human cancers, but their functional and therapeutic significance remains elusive. SF3B1, the most frequently mutated component of the spliceosome in cancer, is involved in the...
2015 / Rachel B. Darman, Michael Seiler, Anant A. Agrawal, Kian H. Lim, Shouyong Peng, et al. -
Computational prediction of protein interfaces: A review of data driven methods
Abstract Reliably pinpointing which specific amino acid residues form the interface(s) between a protein and its binding partner(s) is critical for understanding the structural and physicochemical determinants of protein recognition and binding...
2015 / Li C. Xue, Drena Dobbs, Alexandre M.J.J. Bonvin, Vasant Honavar -
Tumor-Penetrating Peptides2013 / Tambet Teesalu, Kazuki N. Sugahara, Erkki Ruoslahti
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TRP-ing Down the Path to Insulin Secretion2010 / P. E. MacDonald
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Expanding networks of RNA virus evolution2012 / Eugene V Koonin, Valerian V Dolja
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Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction2009 / W. Cao, L. Bover, M. Cho, X. Wen, S. Hanabuchi, et al.