Biological sciences topic list of research papers
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Metagenomic Analysis of Slovak Bryndza Cheese Using Next-Generation 16S rDNA Amplicon Sequencing2016 / Matej Planý, Tomáš Kuchta, Katarína Šoltýs, Tomáš Szemes, Domenico Pangallo, et al.
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Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo
Abstract Differentiation-inducing factor-1 (DIF-1) produced by Dictyostelium discoideum strongly inhibits the proliferation of various types of cancer cells by suppression of the Wnt/β-catenin signal transduction pathway. In the present study, we...
2015 / Naoya Kubokura, Fumi Takahashi-Yanaga, Masaki Arioka, Tatsuya Yoshihara, Kazunobu Igawa, et al. -
Influence of nutrients and currents on the genomic composition of microbes across an upwelling mosaic2012 / Lisa Zeigler Allen, Eric E Allen, Jonathan H Badger, John P McCrow, Ian T Paulsen, et al.
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The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis
Abstract Objective Hypothalamic agouti-related peptide (AgRP) and pro-opiomelanocortin (POMC) expressing neurons play critical roles in control of energy balance. Glutamatergic input via n-methyl-d-aspartate receptors (NMDARs) is...
2015 / Aykut Üner, Gabriel H.M. Gonçalves, Wenjing Li, Matheus Porceban, Nicole Caron, et al. -
Within species support for the expensive tissue hypothesis: a negative association between brain size and visceral fat storage in females of the Pacific seaweed pipefish2016 / Masahito Tsuboi, Jun Shoji, Atsushi Sogabe, Ingrid Ahnesjö, Niclas Kolm
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Disarmed anthrax toxin delivers antisense oligonucleotides and siRNA with high efficiency and low toxicity
Abstract Inefficient cytosolic delivery and vector toxicity contribute to the limited use of antisense oligonucleotides (ASOs) and siRNA as therapeutics. As anthrax toxin (Atx) accesses the cytosol, the purpose of this study was to evaluate the...
2015 / Paul D.R. Dyer, Thomas R. Shepherd, Alexander S. Gollings, Susan A. Shorter, Monique A.M. Gorringe-Pattrick, et al. -
Concept for estimating mitochondrial DNA haplogroups using a maximum likelihood approach (EMMA)
Abstract The assignment of haplogroups to mitochondrial DNA haplotypes contributes substantial value for quality control, not only in forensic genetics but also in population and medical genetics. The availability of Phylotree, a widely accepted...
2013 / Alexander W. Röck, Arne Dür, Mannis van Oven, Walther Parson -
Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP12013 / D S Matassa, M R Amoroso, I Agliarulo, F Maddalena, L Sisinni, et al.
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The retarded hair growth (rhg) mutation in mice is an allele of ornithine aminotransferase (Oat)
Abstract Because of the similar phenotypes they generate and their proximate reported locations on Chromosome 7, we tested the recessive retarded hair growth (rhg) and frizzy (fr) mouse mutations for allelism, but found instead that these defects...
2014 / Jason J. Bisaillon, Legairre A. Radden, Eric T. Szabo, Samantha R. Hughes, Aaron M. Feliciano, et al. -
Association analysis of TPH-1 and TPH-2 genes with suicidal behavior in patients with attempted suicide in Mexican population
Abstract Background Suicidal behavior is a worldwide health problem. Tryptophan hydroxylase (TPH) is a rate limiting enzyme in the biosynthesis of serotonergic neurotransmission. TPH-1 and TPH-2 genes encode for TPH isoforms and...
2015 / María Lilia López-Narváez, Carlos Alfonso Tovilla-Zárate, Thelma Beatriz González-Castro, Isela Juárez-Rojop, Sherezada Pool-García, et al. -
Data supporting the design and evaluation of a universal primer pair for pseudogene-free amplification of HPRT1 in real-time PCR
Abstract Hypoxanthine-guanine phosphoribosyltransferase 1 (HPRT1) is a common housekeeping gene for sample normalization in the quantitative reverse transcriptase polymerase chain (qRT-PCR). However, co-amplification of HPRT1 pseudogenes may affect...
2015 / Reza Valadan, Akbar Hedayatizadeh-Omran, Mahdyieh Naghavi Alhosseini-Abyazani, Omolbanin Amjadi, Alireza Rafiei, et al. -
Advances in T-Cell Epitope Engineering2013 / Johanne M. Pentier, Andrew K. Sewell, John J. Miles
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Adenoma development in familial adenomatous polyposis and MUTYH -associated polyposis: somatic landscape and driver genes2015 / Mamunur Rashid, Andrej Fischer, Cathy H Wilson, Jessamy Tiffen, Alistair G Rust, et al.
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Recent advances in the study of prolamin storage protein organization and function2014 / David R. Holding
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NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice
Abstract Glutathione is the major intracellular redox buffer in the liver and is critical for hepatic detoxification of xenobiotics and other environmental toxins. Hepatic glutathione is also a major systemic store for other organs and thus impacts...
2015 / Thomas V.A. Murray, Xuebin Dong, Greta J. Sawyer, Anna Caldwell, John Halket, et al. -
Roles of FGFs as Adipokines in Adipose Tissue Development, Remodeling, and Metabolism2014 / Hiroya Ohta, Nobuyuki Itoh
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Quantification of female and male Plasmodium falciparum gametocytes by reverse transcriptase quantitative PCR
Abstract The transmission of malaria parasites depends on the presence of sexual stages (gametocytes) in the blood, making the ratio and densities of female and male gametocytes important determinants of parasite fitness. This manuscript describes...
2015 / Petra Schneider, Sarah E. Reece, Ben C.L. van Schaijk, Teun Bousema, Kjerstin H.W. Lanke, et al. -
Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury
Abstract Exacerbated inflammation in renal ischemia–reperfusion injury, the major cause of intrinsic acute renal failure, is a key trigger of kidney damage. During disease endogenous danger signals stimulate innate immune cells via Toll-like...
2014 / Kristin Moreth, Helena Frey, Mario Hubo, Jinyang Zeng-Brouwers, Madalina-Viviana Nastase, et al. -
Disruption of Runx1 and Runx3 Leads to Bone Marrow Failure and Leukemia Predisposition due to Transcriptional and DNA Repair Defects
Summary The RUNX genes encode transcription factors involved in development and human disease. RUNX1 and RUNX3 are frequently associated with leukemias, yet the basis for their involvement in leukemogenesis is not fully understood. Here, we show...
2014 / Chelsia Qiuxia Wang, Vaidehi Krishnan, Lavina Sierra Tay, Desmond Wai Loon Chin, Cai Ping Koh, et al. -
Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model2013 / Nina Cabezas-Wallscheid, Victoria Eichwald, Jos de Graaf, Martin Löwer, Hans-Anton Lehr, et al.