Biological sciences topic list of research papers
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Does Patriline Composition Change over a Honey Bee Queen’s Lifetime?2012 / Robert Brodschneider, Gérard Arnold, Norbert Hrassnigg, Karl Crailsheim
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Effects of second hand smoke on airway secretion and mucociliary clearance2012 / Yanyan Liu, Y. Peter Di
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Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes2013 / Jeong-Hwan Yoon, Su Myung Jung, Seok Hee Park, Mitsuyasu Kato, Tadashi Yamashita, et al.
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The hypothalamic photoreceptors regulating seasonal reproduction in birds: A prime role for VA opsin
Abstract Extraretinal photoreceptors located within the medio-basal hypothalamus regulate the photoperiodic control of seasonal reproduction in birds. An action spectrum for this response describes an opsin photopigment with a λ ...
2014 / José M. García-Fernández, Rafael Cernuda-Cernuda, Wayne I.L. Davies, Jessica Rodgers, Michael Turton, et al. -
Stem cells and bone diseases: New tools, new perspective
Abstract Postnatal skeletal stem cells are a unique class of progenitors with biological properties that extend well beyond the limits of stemness as commonly defined. Skeletal stem cells sustain skeletal tissue homeostasis, organize and maintain...
2014 / Mara Riminucci, Cristina Remoli, Pamela G. Robey, Paolo Bianco -
Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia
Abstract Vascular endothelial growth factor-A (VEGF-A) is best known as a key regulator of the formation of new blood vessels. Neutralization of VEGF-A with anti-VEGF therapy e.g. bevacizumab, can be painful, and this is hypothesized to result from...
2014 / R.P. Hulse, N. Beazley-Long, J. Hua, H. Kennedy, J. Prager, et al. -
Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett’s Esophagus
Background & Aims Barrett's esophagus (BE) increases the risk of esophageal adenocarcinoma (EAC). We found the risk to be BE has been associated with single nucleotide polymorphisms (SNPs) on chromosome 6p21 (within the HLA region) and on...
2014 / Claire Palles, Laura Chegwidden, Xinzhong Li, John M. Findlay, Garry Farnham, et al. -
Nanoparticle-based autoantigen delivery to Treg-inducing liver sinusoidal endothelial cells enables control of autoimmunity in mice
Background & Aims It is well-known that the liver can induce immune tolerance, yet this knowledge could, thus far, not be translated into effective treatments for autoimmune diseases. We have previously shown that liver sinusoidal endothelial ...
2015 / Antonella Carambia, Barbara Freund, Dorothee Schwinge, Oliver T. Bruns, Sunhild C. Salmen, et al. -
Targeting Human Central Nervous System Protein Kinases: An Isoform Selective p38αMAPK Inhibitor That Attenuates Disease Progression in Alzheimer’s Disease Mouse Models2015 / Saktimayee M. Roy, Valerie L. Grum-Tokars, James P. Schavocky, Faisal Saeed, Agnieszka Staniszewski, et al.
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Disease variants in genomes of 44 centenarians2014 / Yun Freudenberg-Hua, Jan Freudenberg, Vladimir Vacic, Avinash Abhyankar, Anne-Katrin Emde, et al.
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Sensitizing tumor cells to radiation by targeting the heat shock response
Abstract Elevated levels of heat shock proteins (HSPs) contribute to tumor cell survival and mediate protection against radiation-induced cell death. Hsp90 inhibitors are promising radiosensitizers but also activate heat shock factor 1 (HSF1) and...
2015 / Daniela Schilling, Annett Kühnel, Sarah Konrad, Fabian Tetzlaff, Christine Bayer, et al. -
Differential effects of angiopoietin-like 4 in brain and muscle on regulation of lipoprotein lipase activity
Abstract Objective Lipoprotein lipase (LPL) is a key regulator of circulating triglyceride rich lipoprotein hydrolysis. In brain LPL regulates appetite and energy expenditure. Angiopoietin-like 4 (Angptl4) is a secreted protein...
2014 / Sara Gry Vienberg, André Kleinridders, Ryo Suzuki, C. Ronald Kahn -
Cancer Karyotypes: Survival of the Fittest2013 / Joshua M. Nicholson, Daniela Cimini
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Carbamylation of immunoglobulin abrogates activation of the classical complement pathway2014 / Catalin Koro, Ewa Bielecka, Anders Dahl-Knudsen, Jan J. Enghild, Carsten Scavenius, et al.
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Tau acts as an independent genetic risk factor in pathologically proven PD
Abstract MAPT has been repeatedly linked with Parkinson's disease (PD) in association studies. Although tau deposition may be seen in PD, its relevance to the pathogenesis of the condition remains unclear. The presence of...
2012 / Gavin Charlesworth, Sonia Gandhi, Jose M. Bras, Roger A. Barker, David J. Burn, et al. -
Piperlongumine inhibits LMP1/MYC-dependent mouse B-lymphoma cells
Abstract Piperlongumine (PL), isolated from the fruit of Long pepper, Piper longum, is a cancer-inhibiting compound that selectively kills tumor cells while sparing their normal counterparts. Here we evaluated the efficacy with which PL suppresses...
2013 / Seong-Su Han, Van S. Tompkins, Dong-Ju Son, Natalie L. Kamberos, Laura L. Stunz, et al. -
Effects of a traditional Chinese medicine, Longdanxiegan formula granule, on Toll-like receptor pathway in female guinea pigs with recurrent genital herpes
Abstract Objective The aim of the present study was to investigate the effects of Longdanxiegan formula granule (LDXGFG), a Chinese traditional medicine on Toll-like receptor (TLR) pathway in recurrent genital herpes. ...
2016 / Lin Kuang, Yihui Deng, Xiaodan Liu, Zhixiang Zou, Lan Mi -
Desiccation tolerance is switched on and off in the resurrection fern, Morhia caffrorum2007 / J.M. Farrant, S. Wiswedel, C. Stowell, A. Lehner
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NOD-Like Receptor Protein 3 Inflammasome Priming and Activation in Barrett’s Epithelial Cells
Background & Aims Microbial molecular products incite intestinal inflammation by activating Toll-like receptors (TLRs) and inflammasomes of the innate immune system. This system’s contribution to esophageal inflammation is not known....
2016 / Yuji Nadatani, Xiaofang Huo, Xi Zhang, Chunhua Yu, Edaire Cheng, et al. -
U.S. Continental Scientific Drilling Community Looks to the Future2011 / Anthony W. Walton