Biological sciences topic list of research papers
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A pipeline for the systematic identification of non-redundant full-ORF cDNAs for polymorphic and evolutionary divergent genomes: Application to the ascidian Ciona intestinalis
Abstract Genome-wide resources, such as collections of cDNA clones encoding for complete proteins (full-ORF clones), are crucial tools for studying the evolution of gene function and genetic interactions. Non-model organisms, in particular marine...
2015 / Michael J. Gilchrist, Daniel Sobral, Pierre Khoueiry, Fabrice Daian, Batiste Laporte, et al. -
Correlation of interferon-lambda 4 ss469415590 with the hepatitis C virus treatment response and its comparison with interleukin 28b polymorphisms in predicting a sustained virological response: a meta-analysis
Summary Background Interferon-lambda 4 (IFNL4) ss469415590 is a newly discovered polymorphism that could predict the treatment response in hepatitis C virus (HCV)-infected patients. This meta-analysis was performed in order to...
2016 / Yunhua Li, Luhua Yang, Kaihui Sha, Tonggang Liu, Liguo Zhang -
Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores
Summary Kinetochores, multisubunit protein assemblies, connect chromosomes to spindle microtubules to promote chromosome segregation. The 10-subunit KMN assembly (comprising KNL1, MIS12, and NDC80 complexes, designated KNL1C, MIS12C, and NDC80C)...
2016 / Arsen Petrovic, Jenny Keller, Yahui Liu, Katharina Overlack, Juliane John, et al. -
Phrenic nerve deficits and neurological immunopathology associated with acute West Nile virus infection in mice and hamsters2016 / Katherine Zukor, Hong Wang, Brett L. Hurst, Venkatraman Siddharthan, Arnaud Van Wettere, et al.
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The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells2015 / Madhav Sharma, Rahul Shinde, Tracy McGaha, Lei Huang, Rikke Holmgaard, et al.
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Ecological parameters of the endohelminths in relation to size and sex of Prochilodus argenteus (Actinopterygii: Prochilodontidae) from the Upper São Francisco River, Minas Gerais, Brazil2010 / Cassandra M. Monteiro, Michelle D. Santos, Nágila A. Zuchi, Marilia C. Brasil-Sato
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TLR7 Agonist GS-9620 Is a Potent Inhibitor of Acute HIV-1 Infection in Human Peripheral Blood Mononuclear Cells2016 / Rujuta A. Bam, Derek Hansen, Alivelu Irrinki, Andrew Mulato, Gregg S. Jones, et al.
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rs2735383, located at a microRNA binding site in the 3’UTR of NBS1, is not associated with breast cancer risk2016 / Jingjing Liu, Ivona Lončar, J. Margriet Collée, Manjeet K. Bolla, Joe Dennis, et al.
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Assembly patterns and functional diversity of tree species in a successional gradient of Araucaria forest in Southern Brazil
Abstract Functional analysis of secondary succession may allow identifying and predicting processes of community assembly, which can be simultaneously driven by factors related to ecological filters and neutral forces. This study evaluated...
2016 / José Vicente-Silva, Rodrigo S. Bergamin, Kátia J. Zanini, Valério D. Pillar, Sandra C. Müller -
Comparison of carnivore, omnivore, and herbivore mammalian genomes with a new leopard assembly2016 / Soonok Kim, Yun Sung Cho, Hak-Min Kim, Oksung Chung, Hyunho Kim, et al.
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Occurrence of the Smallscale Codlet, Bregmaceros nectabanus in the Mediterranean Sea, previously misidentified as B. atlanticus in this region2016 / Antony S. Harold, Daniel Golani
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Current and novel approaches to vaccine development against tuberculosis2012 / Mark J. Cayabyab, Lilia Macovei, Antonio Campos-Neto
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Genus Cistus: a model for exploring labdane-type diterpenes' biosynthesis and a natural source of high value products with biological, aromatic, and pharmacological properties2014 / Dimitra Papaefthimiou, Antigoni Papanikolaou, Vasiliki Falara, Stella Givanoudi, Stefanos Kostas, et al.
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In situ measurement of salinity during seaward migration of Atlantic salmon post-smolts using acoustic transmitters with data-storage capabilities and conventional acoustic transmitters2017 / Hiromichi Mitamura, Eva B. Thorstad, Ingebrigt Uglem, Finn Økland
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Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver
Summary Diurnal oscillations of gene expression controlled by the circadian clock and its connected feeding rhythm enable organisms to coordinate their physiologies with daily environmental cycles. While available techniques yielded crucial insights ...
2016 / Jingkui Wang, Daniel Mauvoisin, Eva Martin, Florian Atger, Antonio Núñes Galindo, et al. -
Alcohol exposure differentially effects anti-tumor immunity in females by altering dendritic cell function
Abstract Dendritic cells (DCs) are a critical component of anti-tumor immunity due to their ability to induce a robust immune response to antigen (Ag). Alcohol was previously shown to reduce DC ability to present foreign Ag and promote...
2016 / Matthew G. Thompson, Flor Navarro, Lennox Chitsike, Luis Ramirez, Elizabeth J. Kovacs, et al. -
High-Throughput Toxicity and Phenotypic Screening of 3D Human Neural Progenitor Cell Cultures on a Microarray Chip Platform
Summary A 3D cell culture chip was used for high-throughput screening of a human neural progenitor cell line. The differential toxicity of 24 compounds was determined on undifferentiated and differentiating NPCs. Five compounds led to significant...
2016 / Gregory J. Nierode, Brian C. Perea, Sean K. McFarland, Jorge F. Pascoal, Douglas S. Clark, et al. -
Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress
Summary MicroRNAs are important regulators of gene expression and associated with stress-related psychiatric disorders. Here, we report that exposing mice to chronic stress led to a specific increase in microRNA-15a levels in the amygdala-Ago2...
2016 / Naama Volk, Julius C. Pape, Mareen Engel, Anthony S. Zannas, Nadia Cattane, et al. -
Glycogen synthase kinase-3β regulates fractalkine production by altering its trafficking from Golgi to plasma membrane: implications for Alzheimer’s disease2016 / Almudena Fuster-Matanzo, Jerónimo Jurado-Arjona, Stefano Benvegnù, Esther García, Patricia Martín-Maestro, et al.
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The Role of PDGFR-β Activation in Acquired Resistance to IGF-1R Blockade in Preclinical Models of Rhabdomyosarcoma
Abstract To determine what alternative pathways may act as mechanisms of bypass resistance to type 1 insulin-like growth factor receptor (IGF-1R) blockade in rhabdomyosarcoma (RMS), we compared expression of receptor tyrosine kinase activity in a...
2016 / Christine M. Heske, Choh Yeung, Arnulfo Mendoza, Joshua T. Baumgart, Leah D. Edessa, et al.