Biological sciences topic list of research papers
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Complexin 3 Increases the Fidelity of Signaling in a Retinal Circuit by Regulating Exocytosis at Ribbon Synapses
Summary Complexin (Cplx) proteins modulate the core SNARE complex to regulate exocytosis. To understand the contributions of Cplx to signaling in a well-characterized neural circuit, we investigated how Cplx3, a retina-specific paralog, shapes...
2016 / Lena S. Mortensen, Silvia J.H. Park, Jiang-bin Ke, Benjamin H. Cooper, Lei Zhang, et al. -
Hydrogen sulfide metabolism regulates endothelial solute barrier function
Abstract Hydrogen sulfide (H2S) is an important gaseous signaling molecule in the cardiovascular system. In addition to free H2S, H2S can be oxidized to polysulfide which can be biologically active. Since the impact of H2S on endothelial solute...
2016 / Shuai Yuan, Sibile Pardue, Xinggui Shen, J. Steven Alexander, A. Wayne Orr, et al. -
Peptidoglycan Recycling in Gram-Positive Bacteria Is Crucial for Survival in Stationary Phase2016 / Marina Borisova, Rosmarie Gaupp, Amanda Duckworth, Alexander Schneider, Désirée Dalügge, et al.
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Integration of next-generation sequencing in clinical diagnostic molecular pathology laboratories for analysis of solid tumours; an expert opinion on behalf of IQN Path ASBL2016 / Zandra C Deans, Jose Luis Costa, Ian Cree, Els Dequeker, Anders Edsjö, et al.
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PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF
Summary In mammalian cells, classical non-homologous end joining (c-NHEJ) is critical for DNA double-strand break repair induced by ionizing radiation and during V(D)J recombination in developing B and T lymphocytes. Recently, PAXX was identified as ...
2016 / Satish K. Tadi, Carine Tellier-Lebègue, Clément Nemoz, Pascal Drevet, Stéphane Audebert, et al. -
Expressions of ion co-transporter genes in salicylate-induced tinnitus and treatment effects of spirulina2016 / Juen-Haur Hwang, Yin-Ching Chan
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Phytochemical Constituents and Toxicity of Duguetia furfuracea Hydroalcoholic Extract in Drosophila melanogaster2014 / Francisca Valéria Soares de Araújo Pinho, Gustavo Felipe da Silva, Giulianna Echeverria Macedo, Katiane Raquel Muller, Illana Kemmerich Martins, et al.
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Oxidative and Nitrosative Stress in the Metastatic Microenvironment2010 / Ángel L. Ortega, Salvador Mena, José M. Estrela
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High concordance between Illumina HiSeq2500 and NextSeq500 for reduced representation bisulfite sequencing (RRBS)
Abstract Reduced representation bisulfite sequencing (RRBS) provides an efficient method for measuring DNA methylation at single base resolution in regions of high CpG density. This technique has been extensively tested on the HiSeq2500, which uses...
2016 / Danqing Yin, Matthew E. Ritchie, Jafar S. Jabbari, Tamara Beck, Marnie E. Blewitt, et al. -
Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation2016 / Valentina Proserpio, Andrea Piccolo, Liora Haim-Vilmovsky, Gozde Kar, Tapio Lönnberg, et al.
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Independent tonotopy and thalamocortical projection patterns in two adjacent parts of the classical primary auditory cortex in mice
Abstract Amid recent amendment of delineation of a mouse auditory cortical map, a caudal auditory field, originally defined as the primary auditory cortex (AI), was divided into the AI and dorsomedial field (DM), based on distinct high frequency...
2016 / Hiroaki Tsukano, Masao Horie, Kuniyuki Takahashi, Ryuichi Hishida, Hirohide Takebayashi, et al. -
Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility “Hot-Spot”2010 / Sharon E. Johnatty, Jonathan Beesley, Xiaoqing Chen, Stuart Macgregor, David L. Duffy, et al.
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Genotype-Phenotype Analysis in Congenital Adrenal Hyperplasia due to P450 Oxidoreductase Deficiency2011 / Nils Krone, Nicole Reisch, Jan Idkowiak, Vivek Dhir, Hannah E. Ivison, et al.
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Mitogen-activated protein kinases regulate expression of neuronal nitric oxide synthase and neurite outgrowth via non-classical retinoic acid receptor signaling in human neuroblastoma SH-SY5Y cells
Abstract We have previously shown that retinoic acid receptor (RAR) stimulation by an agonist Am80 recruits nitric oxide-dependent signaling via increased expression of neuronal nitric oxide synthase (nNOS) in rat midbrain slice cultures. Using...
2015 / Tatsuya Fujibayashi, Yuki Kurauchi, Akinori Hisatsune, Takahiro Seki, Koichi Shudo, et al. -
Risperidone-induced weight gain is mediated through shifts in the gut microbiome and suppression of energy expenditure
Abstract Risperidone is a second-generation antipsychotic that causes weight gain. We hypothesized that risperidone-induced shifts in the gut microbiome are mechanistically involved in its metabolic consequences. Wild-type female C57BL/6J mice...
2015 / Sarah M. Bahr, Benjamin J. Weidemann, Ana N. Castro, John W. Walsh, Orlando deLeon, et al. -
Surface water areas significantly impacted 2014 dengue outbreaks in Guangzhou, China
Abstract Dengue transmission in urban areas is strongly influenced by a range of biological and environmental factors, yet the key drivers still need further exploration. To better understand mechanisms of environment–mosquito–urban dengue...
2016 / Huaiyu Tian, Shanqian Huang, Sen Zhou, Peng Bi, Zhicong Yang, et al. -
Ribosome profiling reveals an adaptation strategy of reduced bacterium to acute stress
Abstract Bacteria of class Mollicutes (mycoplasmas) feature significant genome reduction which makes them good model organisms for systems biology studies. Previously we demonstrated, that drastic transcriptional response of mycoplasmas to stress...
2016 / Gleb Y. Fisunov, Daria V. Evsyutina, Irina A. Garanina, Alexander A. Arzamasov, Ivan O. Butenko, et al. -
First pregnancy characteristics, postmenopausal breast density, and salivary sex hormone levels in a population at high risk for breast cancer
Abstract Background It remains unknown if later life breast cancer risk as determined by reproductive history is mediated by postmenopausal breast density and/or sex steroid levels. ...
2015 / Mary Mockus, LeeAnn Prebil, Rochelle Ereman, Charles Dollbaum, Mark Powell, et al. -
Antibody H3 Structure Prediction
Abstract Antibodies are proteins of the immune system that are able to bind to a huge variety of different substances, making them attractive candidates for therapeutic applications. Antibody structures have the potential to be useful during drug...
2017 / C. Marks, C.M. Deane -
Application of a new PCR-RFLP panel suggests a restricted population structure for Eimeria tenella in UK and Irish chickens
Abstract Eimeria species cause coccidiosis, most notably in chickens where the global cost exceeds US$3 billion every year. Understanding variation in Eimeria population structure and genetic diversity contributes valuable...
2016 / Elaine Pegg, Kate Doyle, Emily L. Clark, Isa D. Jatau, Fiona M. Tomley, et al.