Biological sciences topic list of research papers
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Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia2016 / Zhaohui Gu, Michelle Churchman, Kathryn Roberts, Yongjin Li, Yu Liu, et al.
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Activation of WNT/β-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61
Abstract Pancreatic ductal adenocarcinoma (PDAC), a poor prognostic cancer, commonly develops following activating mutations in the KRAS oncogene. Activation of WNT signaling is also commonly observed in PDAC. To ascertain the impact of postnatal...
2016 / Makoto Sano, David R. Driscoll, Wilfredo E. DeJesus-Monge, Brian Quattrochi, Victoria A. Appleman, et al. -
Impaired Lymphocytes Development and Xenotransplantation of Gastrointestinal Tumor Cells in Prkdc-Null SCID Zebrafish Model
Abstract Severe combined immunodeficiency (SCID) mice have widely been used as hosts for human tumor cell xenograft study. This animal model, however, is labor intensive. As zebrafish is largely emerging as a promising model system for studying...
2016 / In Hye Jung, Yong-Yoon Chung, Dawoon E. Jung, Young Jin Kim, Do Hee Kim, et al. -
Laryngeal mucus hypersecretion is exacerbated after smoking cessation and ameliorated by glucocorticoid administration
Abstract Introduction The mechanisms underlying the effects of cigarette smoke and smoking cessation on respiratory secretion, especially in the larynx, remain unclear. Objectives ...
2016 / Rumi Ueha, Satoshi Ueha, Kenji Kondo, Takaharu Nito, Yoko Fujimaki, et al. -
Draft genome sequence of Microbacterium oleivorans strain Wellendorf implicates heterotrophic versatility and bioremediation potential
Abstract Microbacterium oleivorans is a predominant member of hydrocarbon-contaminated environments. We here report on the genomic analysis of M. oleivorans strain Wellendorf that was isolated from an indoor door handle. The...
2016 / Anton P. Avramov, M.B. Couger, Emily L. Hartley, Craig Land, Rachel Wellendorf, et al. -
Naturalistic rapid deceleration data: Drivers aged 75 years and older
Abstract The data presented in this article are related to the research manuscript “Predictors of older drivers’ involvement in rapid deceleration events”, which investigates potential predictors of older drivers’ involvement in rapid deceleration...
2016 / Anna Chevalier, Aran John Chevalier, Elizabeth Clarke, Kristy Coxon, Julie Brown, et al. -
Adenovirus Protein E4-ORF1 Activation of PI3 Kinase Reveals Differential Regulation of Downstream Effector Pathways in Adipocytes
Summary Insulin activation of phosphatidylinositol 3-kinase (PI3K) regulates metabolism, including the translocation of the Glut4 glucose transporter to the plasma membrane and inactivation of the FoxO1 transcription factor. Adenoviral protein...
2016 / Natasha Chaudhary, Eva Gonzalez, Sung-Hee Chang, Fuqiang Geng, Shahin Rafii, et al. -
Vitrification of mouse MII oocytes: Developmental competency using paclitaxel
Abstract Objective Oocyte cryopreservation provides an important alternative for fertility preservation for women who will be treated with cytotoxic drugs. However, it can cause spindle disorganization of microtubules, putting the...
2016 / Farzaneh Fesahat, Azita Faramarzi, Arezoo Khoradmehr, Marjan Omidi, Fatemeh Anbari, et al. -
Application of next generation sequencing in clinical microbiology and infection prevention
Abstract Current molecular diagnostics of human pathogens provide limited information that is often not sufficient for outbreak and transmission investigation. Next generation sequencing (NGS) determines the DNA sequence of a complete bacterial...
2016 / Ruud H. Deurenberg, Erik Bathoorn, Monika A. Chlebowicz, Natacha Couto, Mithila Ferdous, et al. -
Using genomic repeats for phylogenomics: a case study in wild tomatoes ( Solanum section Lycopersicon : Solanaceae)2015 / Steven Dodsworth, Mark W. Chase, Tiina Särkinen, Sandra Knapp, Andrew R. Leitch
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Are obesity risk genes associated with binge eating in adolescence?2015 / Nadia Micali, Alison E. Field, Janet L. Treasure, David M. Evans
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The metabolomics of asthma control: a promising link between genetics and disease2015 / Michael J. McGeachie, Amber Dahlin, Weiliang Qiu, Damien C. Croteau-Chonka, Jessica Savage, et al.
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Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants2016 / Michelle L. Krishnan, Zi Wang, Matt Silver, James P. Boardman, Gareth Ball, et al.
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The mesencephalic locomotor region sends a bilateral glutamatergic drive to hindbrain reticulospinal neurons in a tetrapod2015 / Dimitri Ryczko, Francois Auclair, Jean-Marie Cabelguen, Réjean Dubuc
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Loss of Endometrial Plasticity in Recurrent Pregnancy Loss2015 / Emma S. Lucas, Nigel P. Dyer, Keisuke Murakami, Yie Hou Lee, Yi-Wah Chan, et al.
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Efeito da aplicação de baixa temperatura em plantas de macieira sobre o crescimento durante a aclimatização2007 / Jonny Everson Scherwinski Pereira, Gerson Renan de Luces Fortes, João Baptista da Silva
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Depletion of CD11c + cells in the CD11c.DTR model drives expansion of unique CD64 + Ly6C + monocytes that are poised to release TNF-α2015 / Shivajanani Sivakumaran, Stephen Henderson, Sophie Ward, Pedro Santos E. Sousa, Teresa Manzo, et al.
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Sexually dimorphic brain fatty acid composition in low and high fat diet-fed mice
Abstract Objective In this study, we analyzed the fatty acid profile of brains and plasma from male and female mice fed chow or a western-style high fat diet (WD) for 16 weeks to determine if males and females process fatty acids...
2016 / Carlos Rodriguez-Navas, Eugenia Morselli, Deborah J. Clegg -
LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex
Summary Cell migration requires coordination between integrin-mediated cell adhesion to the extracellular matrix and force applied to adhesion sites. Talin plays a key role in coupling integrin receptors to the actomyosin contractile machinery,...
2016 / Thomas Zacharchenko, Xiaolan Qian, Benjamin T. Goult, Devina Jethwa, Teresa B. Almeida, et al. -
Differential gene expression during early development in brains of wildtype and biotinidase-deficient mice
Abstract Biotinidase deficiency is an autosomal recessively inherited disorder characterized by neurological and cutaneous abnormalities. Untreated individuals with biotinidase deficiency cannot recycle biotin from biocytin (N-biotinyl-ϵ-lysine),...
2016 / Christian Brigolin, Nathan McKenty, Kirit Pindolia, Barry Wolf