Biological sciences topic list of research papers
-
Complete genome sequence of Capnocytophaga ochracea type strain (VPI 2845T)2009 / Konstantinos Mavrommatis, Sabine Gronow, Elizabeth Saunders, Miriam Land, Alla Lapidus, et al.
-
Farnesoid X receptor, the bile acid sensing nuclear receptor, in liver regeneration
Abstract The liver is unique in regenerative potential, which could recover the lost mass and function after injury from ischemia and resection. The underlying molecular mechanisms of liver regeneration have been extensively studied in the past...
2015 / Guodong Li, Grace L. Guo -
Note on predation of the brood of Mischocyttarus injucundus (de Saussure) by another social wasp in Caxiuanã, Pará, Brazil, with new records of species for the Ferreira Penna Research Station (Hymenoptera, Vespidae, Polistinae)2015 / Orlando Tobias Silveira, Sherlem Patricia de Seixas Felizardo, Suzy Melry Cardoso dos Santos
-
The prevention of radiation-induced DNA damage and apoptosis in human intestinal epithelial cells by salvianic acid A
Abstract The topic of radiation always provokes public debate, and the uses of radiation for therapeutic and other purposes have always been associated with some anxiety. Salvia miltiorrhiza Bunge has been widely used for the treatment of various...
2014 / Yanjun Zhang, Juan Guo, Yuhong Qi, Qiuju Shao, Jun Liang -
Differential effects of altered patterns of movement and strain on joint cell behaviour and skeletal morphogenesis
Summary Objective There is increasing evidence that joint shape is a potent predictor of osteoarthritis (OA) risk; yet the cellular events underpinning joint morphogenesis remain unclear. We sought to develop a genetically...
2016 / L.H. Brunt, R.E.H. Skinner, K.A. Roddy, N.M. Araujo, E.J. Rayfield, et al. -
Substrate binding induces structural changes in cytochrome P450cam2009 / Keisuke Sakurai, Hideo Shimada, Takashi Hayashi, Tomitake Tsukihara
-
MARK-AGE population: From the human model to new insights2015 / Miriam Capri, María Moreno-Villanueva, Elisa Cevenini, Elisa Pini, Maria Scurti, et al.
-
TRMT5 Mutations Cause a Defect in Post-transcriptional Modification of Mitochondrial tRNA Associated with Multiple Respiratory-Chain Deficiencies
Deficiencies in respiratory-chain complexes lead to a variety of clinical phenotypes resulting from inadequate energy production by the mitochondrial oxidative phosphorylation system. Defective expression of mtDNA-encoded genes, caused by mutations in either the...
2015 / Christopher A. Powell, Robert Kopajtich, Aaron R. D’Souza, Joanna Rorbach, Laura S. Kremer, et al. -
The mannose-6-phosphate analogue, PXS64, inhibits fibrosis via TGF-β1 pathway in human lung fibroblasts
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic disease characterised by a progressive decline in lung function which can be attributed to excessive scarring, inflammation and airway remodelling. Mannose-6-phosphate (M6P) is a strong...
2015 / Heidi Schilter, Carmen Z. Cantemir-Stone, Vladimir Leksa, Anna Ohradanova-Repic, Alison D. Findlay, et al. -
Paget disease of bone-associated UBA domain mutations of SQSTM1 exert distinct effects on protein structure and function
Abstract SQSTM1 mutations are common in patients with Paget disease of bone (PDB), with most affecting the C-terminal ubiquitin-associated (UBA) domain of the SQSTM1 protein. We performed structural and functional analyses of...
2014 / Alice Goode, Jed E. Long, Barry Shaw, Stuart H. Ralston, Micaela Rios Visconti, et al. -
The effects of Zibu Piyin Recipe components on scopolamine-induced learning and memory impairment in the mouse
Abstract Ethnopharmacological relevance The Zibu Piyin Recipe (ZBPYR) is derived from Zicheng Decoction, a traditional Chinese medicine formula recorded in the book of Bujuji, written by Wu Cheng in the Qing dynasty and used for...
2013 / Liying Zhu, Lin Zhang, Libin Zhan, Xiaoguang Lu, Jinyong Peng, et al. -
The green bullwhip effect: Transferring environmental requirements along a supply chain
Abstract The bullwhip effect has long been recognized as a critical factor that amplifies demand variability as customer orders pass upstream through successive tiers of a supply chain. Like customer demand, environmental requirements also change...
2014 / Su-Yol Lee, Robert D. Klassen, Andrea Furlan, Andrea Vinelli -
Vaccination with Leishmania mexicana LPG induces PD-1 in CD8+ and PD-L2 in macrophages thereby suppressing the immune response: A model to assess vaccine efficacy
Abstract Leishmania lipophosphoglycan (LPG) is a molecule that has been used as a vaccine candidate, with contradictory results. Since unsuccessful protection could be related to suppressed T cell responses, we analyzed the...
2014 / M.B. Martínez Salazar, J. Delgado Domínguez, J. Silva Estrada, C. González Bonilla, I. Becker -
A deletion in the intergenic region upstream of Ednrb causes head spot in the rat strain KFRS4/Kyo2017 / Minako Yoshihara, Tetsuya Sato, Daisuke Saito, Osamu Ohara, Takashi Kuramoto, et al.
-
Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations
Abstract The enzyme complex γ-secretase generates amyloid β-peptide (Aβ), a 37–43-residue peptide associated with Alzheimer disease (AD). Mutations in presenilin 1 (PS1), the catalytical subunit of γ-secretase, result in familial AD (FAD). A...
2014 / Johanna Wanngren, Patricia Lara, Karin Öjemalm, Silvia Maioli, Nasim Moradi, et al. -
Population heterogeneity and dynamics in starter culture and lag phase adaptation of the spoilage yeast Zygosaccharomyces bailii to weak acid preservatives
Abstract The food spoilage yeast Zygosaccharomyces bailii shows great resistance to weak-acid preservatives, including sorbic acid (2, 4-hexadienoic acid). That extreme resistance was shown to be due to population heterogeneity, with a small...
2014 / Malcolm Stratford, Hazel Steels, Gerhard Nebe-von-Caron, Simon V. Avery, Michaela Novodvorska, et al. -
Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV-W proviral insertions and processed pseudogenes2016 / Nicole Grandi, Marta Cadeddu, Jonas Blomberg, Enzo Tramontano
-
A second component of the SltA-dependent cation tolerance pathway in Aspergillus nidulans
Abstract The transcriptional response to alkali metal cation stress is mediated by the zinc finger transcription factor SltA in Aspergillus nidulans and probably in other fungi of the pezizomycotina subphylum. A second component of this pathway has...
2015 / Laura Mellado, Ana Maria Calcagno-Pizarelli, Robin A. Lockington, Marc S. Cortese, Joan M. Kelly, et al. -
Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach
Abstract Due to many favourable attributes adenoviruses (Ads) are the most extensively used vectors for clinical gene therapy applications. However, following intravascular administration, the safety and efficacy of Ad vectors are hampered by the...
2013 / Margaret R. Duffy, Alan L. Parker, Eric R. Kalkman, Katie White, Dmytro Kovalskyy, et al. -
Relating genomic characteristics to environmental preferences and ubiquity in different microbial taxa2017 / Marta Cobo-Simón, Javier Tamames