Biological sciences topic list of research papers
-
Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance
Summary B cells are unique antigen-presenting cells because their antigen presentation machinery is closely tied to the B cell receptor. Autoreactive thymic B cells can efficiently present cognate self-antigens to mediate CD4+ T cell-negative...
2016 / Jason Perera, Zhong Zheng, Shuyin Li, Herman Gudjonson, Olga Kalinina, et al. -
Injury due to extravasation of thiopental and propofol: Risks/effects of local cooling/warming in rats
Abstract Inadvertent leakage of medications with vesicant properties can cause severe necrosis in tissue, which can have devastating long-term consequences. The aim of this study was to evaluate the extent of extravasation injury induced by...
2016 / Yuuka Shibata, Tomoharu Yokooji, Ryo Itamura, Yumeka Sagara, Takanori Taogoshi, et al. -
Ploidy level in the genusLeucanthemumcorrelates with resistance to a specialist herbivore2016 / Sonja Stutz, Hariet L. Hinz, Kamil Konowalik, Heinz Müller-Schärer, Christoph Oberprieler, et al.
-
Detection of Clinically Relevant Genetic Variants in Autism Spectrum Disorder by Whole-Genome Sequencing
Autism Spectrum Disorder (ASD) demonstrates high heritability and familial clustering, yet the genetic causes remain only partially understood as a result of extensive clinical and genomic heterogeneity. Whole-genome sequencing (WGS) shows promise as a tool for...
2013 / Yong-hui Jiang, Ryan K.C. Yuen, Xin Jin, Mingbang Wang, Nong Chen, et al. -
Characterization of a potential ABC-type bacteriocin exporter protein from Treponema denticola2016 / Kimiko Tanaka-Kumazawa, Yuichiro Kikuchi, Yumiko Sano-Kokubun, Seikou Shintani, Masashi Yakushiji, et al.
-
Implementing non-image-forming effects of light in the built environment: A review on what we need
Abstract This paper presents a theoretical framework for incorporating the non-image-forming effects of light into daylighting design in the built environment. The framework includes human performance indicators to measure the magnitude of the...
2016 / P. Khademagha, M.B.C. Aries, A.L.P. Rosemann, E.J. van Loenen -
Glycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapy2016 / Takahiro Domoto, Ilya V. Pyko, Takuya Furuta, Katsuyoshi Miyashita, Masahiro Uehara, et al.
-
Detection of multidrug-resistant Mycobacterium tuberculosis strains isolated in Brazil using a multimarker genetic assay for katG and rpoB genes
Abstract Multidrug-resistant tuberculosis (MDRTB) is a serious world health problem that limits public actions to control tuberculosis, because the most used anti-tuberculosis first-line drugs fail to stop mycobacterium spread. Consequently, a quick ...
2016 / Luita Nice Café Oliveira, Jairo da Silva Muniz-Sobrinho, Luiz Alexandre Viana-Magno, Sônia Cristina Oliveira Melo, Antonio Macho, et al. -
Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum2015 / Claudia Moriconi, Adriana Ordoñez, Giuseppe Lupo, Bibek Gooptu, James A. Irving, et al.
-
Assessment of the influence of intrinsic environmental and geographical factors on the bacterial ecology of pit latrines2016 / Belen Torondel, Jeroen H.J. Ensink, Ozan Gundogdu, Umer Zeeshan Ijaz, Julian Parkhill, et al.
-
Tat-antioxidant 1 protects against stress-induced hippocampal HT-22 cells death and attenuate ischaemic insult in animal model2015 / So Mi Kim, In Koo Hwang, Dae Young Yoo, Won Sik Eum, Dae Won Kim, et al.
-
Dataset of differentially regulated proteins in HUVECs challenged with wild type and UGM1 mutant Aspergillus fumigatus strains
Abstract Invasive aspergillosis is the primary opportunistic invasive fungal infection described in neutropenic hematologic patients, caused by the angioinvasive pathogen Aspergillus fumigatus. The molecular mechanisms associated...
2016 / Gabriela Westerlund Peixoto Neves, Nathália Curty, Paula Helena Kubitschek-Barreira, Thierry Fontaine, Gustavo Henrique Martins Ferreira Souza, et al. -
Acrolein Is a Pathogenic Mediator of Alcoholic Liver Disease and the Scavenger Hydralazine Is Protective in Mice
Background & Aims Alcoholic liver disease (ALD) remains a major cause of morbidity and mortality, with no Food and Drug Administration–approved therapy. Chronic alcohol consumption causes a pro-oxidant environment and increases hepatic lipid...
2016 / Wei-Yang Chen, Jingwen Zhang, Smita Ghare, Shirish Barve, Craig McClain, et al. -
Testing Taxon Tenacity of Tortoises: evidence for a geographical selection gradient at a secondary contact zone2015 / Taylor Edwards, Kristin H. Berry, Richard D. Inman, Todd C. Esque, Kenneth E. Nussear, et al.
-
Extremely high proportions of male flowers and geographic variation in floral ratios within male figs of Ficus tikoua despite pollinators displaying active pollen collection2016 / Jun-Yin Deng, Rong-Hua Fu, Stephen G. Compton, Dai-Mei Hu, Lu-Shui Zhang, et al.
-
Whole genome sequencing to complement tuberculosis drug resistance surveys in Uganda
Abstract Understanding the circulating Mycobacterium tuberculosis resistance mutations is vital for better TB control strategies, especially to inform a new MDR-TB treatment programme. We complemented the phenotypic drug susceptibility testing (DST) ...
2016 / Willy Ssengooba, Conor J. Meehan, Deus Lukoye, George William Kasule, Kenneth Musisi, et al. -
Datasets for transcriptomic analyses of maize leaves in response to Asian corn borer feeding and/or jasmonic acid
Abstract Corn is one of the most widely grown crops throughout the world. However, many corn fields develop pest problems such as corn borers every year that seriously affect its yield and quality. Corn′s response to initial insect damage involves a ...
2016 / Yuliang Zhang, Qixing Huang, Kayla K. Pennerman, Jiujiang Yu, Zhixin Liu, et al. -
Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes
Abstract Our analysis examines the conservation of multiprotein complexes among metazoa through use of high resolution biochemical fractionation and precision mass spectrometry applied to soluble cell extracts from 5 representative model organisms...
2015 / Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, et al. -
Differentiation of Human Embryonic Stem Cells to Endothelial Progenitor Cells on Laminins in Defined and Xeno-free Systems
Summary A major hurdle for in vitro culturing of primary endothelial cells (ECs) is that they readily dedifferentiate, hampering their use for therapeutic applications. Human embryonic stem cells (hESCs) may provide an unlimited cell source;...
2016 / Mien T.X. Nguyen, Elena Okina, Xiaoran Chai, Kok Hian Tan, Outi Hovatta, et al. -
Laboratory evaluation of Clusia fluminensis extracts and their isolated compounds against Dysdercus peruvianus and Oncopeltus fasciatus2016 / Rodrigo C. Duprat, Maria C. Anholeti, Bruno P. de Sousa, João P.F. Pacheco, Maria R. Figueiredo, et al.