Biological sciences topic list of research papers
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IL-1β/NF-kb signaling promotes colorectal cancer cell growth through miR-181a/PTEN axis
Abstract To date, the role of miRNA in tumorigenesis has been largely reported. It was found that miR-181a may be involved in the tumorigenesis of colon cancer. The purpose of this study was to investigate the mechanism of miR-181a in colon cancer...
2016 / Pei Hai ping, Tan Feng bo, Liu Li, Yu Nan hui, Zhu Hong -
Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization2009 / Jeong-Ah Shin, Hun Chang, Se-Min Park, An-Soo Jang, Sung Park, et al.
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VRK1 phosphorylates and protects NBS1 from ubiquitination and proteasomal degradation in response to DNA damage
Abstract NBS1 is an early component in DNA-Damage Response (DDR) that participates in the initiation of the responses aiming to repair double-strand breaks caused by different mechanisms. Early steps in DDR have to react to local alterations in...
2016 / Diana M. Monsalve, Ignacio Campillo-Marcos, Marcella Salzano, Marta Sanz-García, Lara Cantarero, et al. -
LEDGIN-mediated Inhibition of Integrase–LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV
Abstract Persistence of latent, replication-competent Human Immunodeficiency Virus type 1 (HIV-1) provirus is the main impediment towards a cure for HIV/AIDS (Acquired Immune Deficiency Syndrome). Therefore, different therapeutic strategies to...
2016 / Lenard S. Vranckx, Jonas Demeulemeester, Suha Saleh, Annegret Boll, Gerlinde Vansant, et al. -
Species interactions can maintain resistance of subtidal algal habitats to an increasingly modified world
Abstract Current trends in habitat loss have been forecast to accelerate under anticipated global change, thereby focusing conservation attention on identifying the circumstances under which key species interactions retard habitat loss. Urbanised...
2015 / Laura J. Falkenberg, Sean D. Connell, Owen I. Coffee, Giulia Ghedini, Bayden D. Russell -
Multiple Immune-Modulatory Functions Of Cathelicidin Host Defense Peptides2012 / Ka-Yee (Grace) Choi, Neeloffer Mookherjee
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Mitochondrial Protection by Exogenous Otx2 in Mouse Retinal Neurons
Summary OTX2 (orthodenticle homeobox 2) haplodeficiency causes diverse defects in mammalian visual systems ranging from retinal dysfunction to anophthalmia. We find that the retinal dystrophy of Otx2 ...
2015 / Hyoung-Tai Kim, Soung Jung Kim, Young-In Sohn, Sun-Sook Paik, Romain Caplette, et al. -
In vitro comparative analysis of human dental stem cells from a single donor and its neuronal differentiation potential evaluated by electrophysiology
Abstract Aims The aim of this study was to find out a mesenchymal stem cells (MSCs) source from human dental tissues of the same donor (follicle, papilla and pulp), which exhibits higher neurogenic differentiation potential in...
2016 / Imran Ullah, Raghavendra Baregundi Subbarao, Eun-Jin Kim, Dinesh Bharti, Si-Jung Jang, et al. -
Catalogue of Anisopodidae (Diptera, Bibionomorpha) types housed in the collection of the Museu de Zoologia da Universidade de São Paulo, Brazil2015 / Rafaela L. Falaschi, Sarah Siqueira Oliveira, Carlos J.E. Lamas
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Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase
Summary The attenuation of protein synthesis via the phosphorylation of eIF2α is a major stress response of all eukaryotic cells. The growth-arrest- and DNA-damage-induced transcript 34 (GADD34) bound to the serine/threonine protein phosphatase 1...
2015 / Meng S. Choy, Permeen Yusoff, Irene C. Lee, Jocelyn C. Newton, Catherine W. Goh, et al. -
A tale of two neglected systems—structure and function of the thin- and thick-walled sieve tubes in monocotyledonous leaves2013 / C. E. J. Botha
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Live prey enrichment and artificial microdiets for larviculture of Atlantic red porgy Pagrus pagrus
Abstract In the first experiment the effects of rotifer enrichment and feeding frequency on larval performance of red porgy Pagrus pagrus were studied. Larvae (2 days post-hatching=2dph) were fed s-type rotifers (∼20 rotifers/mL) enriched with one...
2016 / Wade O. Watanabe, Md. Shah Alam, Andrew D. Ostrowski, Frank A. Montgomery, Jennifer E. Gabel, et al. -
Generation of KCL012 research grade human embryonic stem cell line carrying a mutation in the HTT gene
Abstract The KCL012 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the HTT gene encoding huntingtin (46 trinucleotide repeats; 17 for the normal...
2016 / Laureen Jacquet, Heema Hewitson, Victoria Wood, Neli Kadeva, Glenda Cornwell, et al. -
The risk of exploitation during communal nursing in house mice, Mus musculus domesticus
Parental care is associated with costs. Communal offspring care in species with altricial young may reduce the costs for a parent, but it comes with a risk of exploitation, jeopardizing the evolution of stable cooperation. Female house mice can either rear their...
2015 / Manuela Ferrari, Anna K. Lindholm, Barbara König -
Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND)2016 / Robert C. Williams, Robert C. Elston, Pankaj Kumar, William C. Knowler, Hanna E. Abboud, et al.
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Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2014–2015
Abstract The World Health Organization (WHO) Collaborating Centres for Reference and Research on Influenza (WHO CCs) tested 13,312 viruses collected by WHO recognized National Influenza Centres between May 2014 and May 2015 to determine 50%...
2016 / Aeron C. Hurt, Terry G. Besselaar, Rod S. Daniels, Burcu Ermetal, Alicia Fry, et al. -
Oyster extracts attenuate pathological changes in non-alcoholic steatohepatitis (NASH) mouse model
Abstract The phenolic compound 3,5-dihydroxy-4-methoxybenzyl alcohol (DHMBA) is a natural antioxidant recently isolated from the Pacific oyster. DHMBA, up to a concentration of 500 µM, has demonstrated a strong in vitro hepatocyte-protective effect...
2015 / Mitsugu Watanabe, Hirotoshi Fuda, Hiroaki Okabe, Sae Joko, Yusuke Miura, et al. -
A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN
Summary The cellular response to replication stress requires the DNA-damage-responsive kinase ATM and its cofactor ATMIN; however, the roles of this signaling pathway following replication stress are unclear. To identify the functions of ATM and...
2016 / Abdelghani Mazouzi, Alexey Stukalov, André C. Müller, Doris Chen, Marc Wiedner, et al. -
A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals
Abstract Background Quantifying latently infected cells is critical to evaluate the efficacy of therapeutic strategies aimed at reducing the size of the long-lived viral reservoir, but the low frequency of these cells makes this...
2015 / Francesco Andrea Procopio, Rémi Fromentin, Deanna A. Kulpa, Jessica H. Brehm, Anne-Gaelle Bebin, et al. -
Generation of KCL026 research grade human embryonic stem cell line carrying a mutation in SMN1 gene
Abstract The KCL026 human embryonic stem cell line was derived from an embryo donated for research that carried a mutation in the SMN1 gene encoding survival of motor neuron 1, telomeric (exons 7 and 8 deletion). Mutations in this gene are...
2016 / Heema Hewitson, Victoria Wood, Neli Kadeva, Glenda Cornwell, Stefano Codognotto, et al.