Biological sciences topic list of research papers
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A Mouse Model That Reproduces the Developmental Pathways and Site Specificity of the Cancers Associated With the Human BRCA1 Mutation Carrier State
ABSTRACT Predisposition to breast and extrauterine Müllerian carcinomas in BRCA1 mutation carriers is due to a combination of cell-autonomous consequences of BRCA1 inactivation on cell cycle homeostasis superimposed on cell-nonautonomous hormonal...
2015 / Ying Liu, Hai-Yun Yen, Theresa Austria, Jonas Pettersson, Janos Peti-Peterdi, et al. -
N-terminal Dentin Sialoprotein fragment induces type I collagen production and upregulates dentinogenesis marker expression in osteoblasts
Abstract Bone and dentin are mineralized extracellular matrices produced by osteoblasts and odontoblasts, respectively, and their major organic portion is type I collagen. Dentinogenesis Imperfecta (DGI) is one of the most common clinically- and...
2016 / Haytham Jaha, Dina Husein, Yoshio Ohyama, Dongliang Xu, Shigeki Suzuki, et al. -
CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells
Summary The generation of tissue-specific cell types from human embryonic stem cells (hESCs) is critical for the development of future stem cell-based regenerative therapies. Here, we identify CD13 and ROR2 as cell-surface markers capable of...
2016 / Rhys J.P. Skelton, Bevin Brady, Suhail Khoja, Debashis Sahoo, James Engel, et al. -
ABC-B transporter genes in Dirofilaria immitis
Abstract Dirofilaria immitis is a filarial nematode causing infection and heartworm disease in dogs and other canids, cats, and occasionally in humans. Prevention with macrocyclic lactones (ML) is recommended during the...
2016 / Catherine Bourguinat, Hua Che, Thangadurai Mani, Kathy Keller, Roger K. Prichard -
Moderate voluntary exercise attenuates the metabolic syndrome in melanocortin-4 receptor-deficient rats showing central dopaminergic dysregulation
Abstract Objective Melanocortin-4 receptors (MC4Rs) are highly expressed by dopamine-secreting neurons of the mesolimbic tract, but their functional role has not been fully resolved. Voluntary wheel running (VWR) induces...
2015 / Silvana Obici, I. Jack Magrisso, Armen S. Ghazarian, Alireza Shirazian, Jonas R. Miller, et al. -
Inducible protective processes in animal systems XV: Hyperthermia enhances the Ethyl methanesulfonate induced adaptive response in meiotic cells of grasshopper Poecilocerus pictus
Abstract Purpose To understand the role of hyperthermia in adaptive response, Ethyl methanesulfonate (EMS) an anticarcinogenic agent, adapted meiotic cells of Poecilocerus pictus was used. ...
2016 / R. Venu, H.P. Gurushankara, B.B.D. Khalandar, V. Vasudev -
Cause of death in patients with chronic visceral and chronic neurovisceral acid sphingomyelinase deficiency (Niemann-Pick disease type B and B variant): Literature review and report of new cases
Abstract Background Acid sphingomyelinase deficiency (ASMD), [Niemann-Pick Disease Types A and B (NPD A and B)], is an inherited metabolic disorder resulting from deficiency of the lysosomal enzyme acid sphingomyelinase....
2016 / David Cassiman, Seymour Packman, Bruno Bembi, Hadhami Ben Turkia, Moeenaldeen Al-Sayed, et al. -
Timing of changes from a primitive reflex to a voluntary behavior in infancy as a potential predictor of socio-psychological and physical development during juvenile stages among common marmosets
Abstract With regard to socio-psychology, the complexity of a human’s neuronal function develops from initial primitive function to multimodal networking gradually through interaction between innate biological mechanisms and the surrounding...
2015 / Genta Karino, Takayuki Murakoshi, Shun Nakamura, Tetsuya Kunikata, Hideo Yamanouchi, et al. -
Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights into Inner Nuclear Membrane Remodeling
Summary Although nucleo-cytoplasmic transport is typically mediated through nuclear pore complexes, herpesvirus capsids exit the nucleus via a unique vesicular pathway. Together, the conserved herpesvirus proteins pUL31 and pUL34 form the...
2015 / Tzviya Zeev-Ben-Mordehai, Marion Weberruß, Michael Lorenz, Juliana Cheleski, Teresa Hellberg, et al. -
Complete genome sequence of Haliscomenobacter hydrossis type strain (OT)2011 / Hajnalka Daligault, Alla Lapidus, Ahmet Zeytun, Matt Nolan, Susan Lucas, et al.
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Human retinal pigment epithelial cell proliferation by the combined stimulation of hydroquinone and advanced glycation end-products via up-regulation of VEGF gene
Abstract Although recent research showed that advanced glycation endproduct (AGE) and hydroquinone (HQ) are related to the pathogenesis of age-related macular degeneration (AMD), the mechanism how AGE and HQ induce or accelerate AMD remains elusive. ...
2015 / Hiroki Tsujinaka, Asako Itaya-Hironaka, Akiyo Yamauchi, Sumiyo Sakuramoto-Tsuchida, Hiroyo Ota, et al. -
Screening of posttranscriptional regulatory molecules of IκB-ζ
Abstract Posttranscriptional regulatory elements in the 3′-untranslated region (UTR) of mRNAs play an important role in mRNA stabilization. Induction of IκB-ζ, a critical transcriptional regulator in the innate immune response, is mediated via...
2015 / Takashi MaruYama, Aoi Sayama, Ken J. Ishii, Tatsushi Muta -
Variable exon usage of differentially-expressed genes associated with resistance of sheep to Teladorsagia circumcincta
Abstract The resistance and susceptibility of sheep to the common abomasal nematode parasite, Teladorsagia circumcincta is strongly associated with the differential polarization of the immune response. Resistant animals control larval colonization...
2015 / Hazel Wilkie, Siyang Xu, Anton Gossner, John Hopkins -
Conformational changes on ligand binding in wild-type and mutants from Spodoptera frugiperda midgut trehalase
Abstract Trehalase specifically hydrolyses trehalose into two glucose units and is most important in insects and fungi. Previous evidence suggested that Spodoptera frugiperda midgut trehalase (wild type, WT) has substantial conformational changes on ...
2015 / Walciane Silva, Walter R. Terra, Clélia Ferreira -
Permanent draft genome sequence of Dethiosulfovibrio peptidovorans type strain (SEBR 4207T)2010 / Kurt LaButti, Shanmugam Mayilraj, Alicia Clum, Susan Lucas, Tijana Glavina Del Rio, et al.
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Meeting Report: The Terabase Metagenomics Workshop and the Vision of an Earth Microbiome Project2011 / Jack A. Gilbert, Folker Meyer, Dion Antonopoulos, Pavan Balaji, C. Titus Brown, et al.
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α/β-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes
Summary Suppression of α/β-domain hydrolase-6 (ABHD6), a monoacylglycerol (MAG) hydrolase, promotes glucose-stimulated insulin secretion by pancreatic β cells. We report here that high-fat-diet-fed ABHD6-KO mice show modestly reduced food intake,...
2016 / Shangang Zhao, Yves Mugabo, Gwynne Ballentine, Camille Attane, Jose Iglesias, et al. -
Study on the genus Daptus ground-beetles (Coleoptera: Carabidae) from Korea
Abstract A genus Daptus Fischer von Waldheim, 1823 of the tribe Harpalini Bonelli, 1810 (Coleoptera: Carabidae) is reported for the first time from Korea, based on the Daptus vittatus Fischer von Waldheim from Incheon, Korea. Redescription of the...
2016 / Ik Je Choi, Jongok Lim, Jinyoung Park, Ji Hwan Park, Jong Kyun Park -
Haptoglobin: an emerging candidate for phenotypic modulation of sickle cell anemia?2015 / Magnun Nueldo Nunes dos Santos
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Selection of reference genes for expression analysis in the entomophthoralean fungus Pandora neoaphidis2016 / Chun Chen, Tingna Xie, Sudan Ye, Annette Bruun Jensen, Jørgen Eilenberg