Biological sciences topic list of research papers
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Changing measurements or changing movements? Sampling scale and movement model identifiability across generations of biologging technology2017 / Leah R. Johnson, Philipp H. Boersch-Supan, Richard A. Phillips, Sadie J. Ryan
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Trastuzumab: Updated Mechanisms of Action and Resistance in Breast Cancer2012 / Thuy Vu, Francois X. Claret
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Establishment of SPAST mutant induced pluripotent stem cells (iPSCs) from a hereditary spastic paraplegia (HSP) patient
Abstract Human skin fibroblasts were isolated from a 40-year-old hereditary spastic paraplegia patient carrying an intronic splice site mutation (c.1687+2T>A) in SPAST, leading to hereditary spastic paraplegia type 4 (SPG4). Fibroblasts were...
2016 / Stefan Hauser, Melanie Erzler, Yvonne Theurer, Stefanie Schuster, Rebecca Schüle, et al. -
Elongation factor 2 kinase promotes cell survival by inhibiting protein synthesis without inducing autophagy
Abstract Eukaryotic elongation factor 2 kinase (eEF2K) inhibits the elongation stage of protein synthesis by phosphorylating its only known substrate, eEF2. eEF2K is tightly regulated by nutrient-sensitive signalling pathways. For example, it is...
2016 / Claire E.J. Moore, Xuemin Wang, Jianling Xie, Jo Pickford, John Barron, et al. -
Derivation of the human embryonic stem cell line RCe010-A (RC-6)
Abstract The human embryonic stem cell line RCe010-A (RC-6) was derived from a frozen and thawed blastocyst voluntarily donated as unsuitable and surplus to fertility requirements following ethics committee approved informed consent under licence...
2016 / P.A. De Sousa, B.J. Tye, K. Bruce, P. Dand, G. Russell, et al. -
Responses of soil nematodes to water and nitrogen additions in an old-field grassland
Abstract Given that soil water and nitrogen (N) are two major limiting factors for plant growth, changing precipitation regime and atmospheric N deposition may have profound impacts on ecosystem structure and function. However, the effects of...
2016 / Min Song, Xiaoming Li, Shuishui Jing, Lingjie Lei, Jiali Wang, et al. -
Reduced repair capacity of a DNA clustered damage site comprised of 8-oxo-7,8-dihydro-2′-deoxyguanosine and 2-deoxyribonolactone results in an increased mutagenic potential of these lesions
Abstract A signature of ionizing radiation is the induction of DNA clustered damaged sites. Non-double strand break (DSB) clustered damage has been shown to compromise the base excision repair pathway, extending the lifetimes of the lesions within...
2014 / Siobhan Cunniffe, Peter O’Neill, Marc M. Greenberg, Martine E. Lomax -
ND3, ND1 and 39kDa subunits are more exposed in the de-active form of bovine mitochondrial complex I
Abstract An intriguing feature of mitochondrial complex I from several species is the so-called A/D transition, whereby the idle enzyme spontaneously converts from the active (A) form to the de-active (D) form. The A/D transition plays an important...
2014 / Marion Babot, Paola Labarbuta, Amanda Birch, Sara Kee, Matthew Fuszard, et al. -
Cloning of interleukin-15 gene of Tibetan pig and adjuvant effect of its recombinant plasmids packed with PEG and PEI modified chitosan nanoparticles on immunity of mice to FMD vaccination
Abstract IL-15 cDNA of Tibetan pig was firstly cloned from its activated lymphocytes, and then was sub-cloned into VR1020 to construct recombinant VRTIL-15 plasmid to study the in vitro and in vivo biological effects on animal. The VRTIL-15 was...
2015 / Xiaoping Wan, Xiao Yang, Suqiong Zhan, Jianlin Chen, Wenkui Sun, et al. -
Nordihydroguaiaretic acid (NDGA) and α-mangostin inhibit the growth of Mycobacterium tuberculosis by inducing autophagy
Abstract Tuberculosis (TB) remains as a global health problem. The prevalence of this infection is related to the association with other diseases, such as HIV, neglect treatment and misuse of antibiotics. Hence, the identification of new drugs is...
2015 / Silvia Guzmán-Beltrán, Miguel Ángel Rubio-Badillo, Esmeralda Juárez, Fernando Hernández-Sánchez, Martha Torres -
Cytotoxicity of latex and pharmacobotanical study of leaves and stem of Euphorbia umbellata (Janaúba)2015 / Lívia E.C. Luz, Katia S. Paludo, Vera L.P. Santos, Celia R.C. Franco, Traudi Klein, et al.
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Data for the morphometric characterization of NT2-derived postmitotic neurons
Abstract NTERA2/D1 human teratocarcinoma progenitors induced to differentiate into postmitotic neurons by either long-term treatment with retinoic acid or short-term treatment with the nucleoside analog cytosine β-D-arabinofuranoside were subjected...
2016 / Imanol González-Burguera, Ana Ricobaraza, Xabier Aretxabala, Sergio Barrondo, Gontzal García del Caño, et al. -
Detection of cryptic species of Rugopharynx (Nematoda: Strongylida) from the stomachs of Australian macropodid marsupials
Abstract Sequences of the internal transcribed spacers of nuclear ribosomal DNA (ITS-1 and ITS-2) were determined for species of the genus Rugopharynx and Rugonema labiatum, nematodes from the stomachs of macropodid marsupials. Phylogenetic analyses ...
2016 / Neil B. Chilton, Florence Huby-Chilton, Anson V. Koehler, Robin B. Gasser, Ian Beveridge -
iNOS polymorphism modulates iNOS/NO expression via impaired antioxidant and ROS content in P. vivax and P. falciparum infection
Abstract Nitric oxide (NO) has dicotomic influence on modulating host-parasite interplay, synchronizing physiological orchestrations and diagnostic potential; instigated us to investigate the plausible association and genetic regulation among NO...
2017 / Amod Kumar, Krishn Pratap Singh, Prerna Bali, Shadab Anwar, Asha Kaul, et al. -
Cellular Adjuvant Properties, Direct Cytotoxicity of Re-differentiated Vα24 Invariant NKT-like Cells from Human Induced Pluripotent Stem Cells
Summary Vα24 invariant natural killer T (iNKT) cells are a subset of T lymphocytes implicated in the regulation of broad immune responses. They recognize lipid antigens presented by CD1d on antigen-presenting cells and induce both innate and...
2016 / Shuichi Kitayama, Rong Zhang, Tian-Yi Liu, Norihiro Ueda, Shoichi Iriguchi, et al. -
Brazilian gorgonians: a source of odoriferous compounds?2015 / Silvia Siag Oigman, Yasmin Fróes de Miranda Fernandes, Dany Teles, Lenize Fernandes Maia, Rosângela de Almeida Epifanio, et al.
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Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a R406W mutation in microtubule-associated protein tau (MAPT)
Abstract Skin fibroblasts were obtained from a 59-year-old woman diagnosed with frontotemporal dementia. The disease is caused by a R406W mutation in microtubule-associated protein tau (MAPT). Induced pluripotent stem cells (iPSCs) were established...
2015 / Mikkel A. Rasmussen, Lena E. Hjermind, Lis F. Hasholt, Gunhild Waldemar, Jørgen E. Nielsen, et al. -
Inflammatory signals induce the expression of tonicity-responsive enhancer binding protein (TonEBP) in microglia
Abstract Tonicity-responsive enhancer (TonE) binding protein (TonEBP) is known as an osmosensitive transcription factor that regulates cellular homeostasis during states of hypo- and hypertonic stress. In addition to its role in osmoadaptation,...
2016 / Ga Ram Jeong, Sun-Kyoung Im, Yun-Hee Bae, Eun Su Park, Byung Kwan Jin, et al. -
Patterns of diversity and regeneration in unmanaged moist deciduous forests in response to disturbance in Shiwalik Himalayas, India
Abstract We studied vegetation attributes in Indian tropical moist deciduous unmanaged forests to determine the influence of forest disturbances on them. We enumerated 89 species: 72 under moderate disturbance and 54 under least disturbance. The...
2016 / Mukesh Kumar Gautam, Rajesh Kumar Manhas, Ashutosh Kumar Tripathi -
Evolution of microbial community along with increasing solid concentration during high-solids anaerobic digestion of sewage sludge
Abstract High-solids anaerobic digestion (HSAD), a promising method with smaller reactor and less heating energy consumption, showed relatively lower digestion efficiency sometimes and higher tolerance to some inhibitors. To investigate the...
2016 / Can Liu, Huan Li, Yuyao Zhang, Dandan Si, Qingwu Chen