Biological sciences topic list of research papers
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Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis
Summary The mechanisms by which Mycobacterium tuberculosis (Mtb) maintains metabolic equilibrium to survive during infection and upon exposure to antimycobacterial drugs are poorly characterized. Ergothioneine (EGT) and mycothiol (MSH) are the major ...
2016 / Vikram Saini, Bridgette M. Cumming, Loni Guidry, Dirk A. Lamprecht, John H. Adamson, et al. -
Transcriptomic comparisons between cultured human adipose tissue-derived pericytes and mesenchymal stromal cells
Abstract Mesenchymal stromal cells (MSCs), sometimes called mesenchymal stem cells, are cultured cells able to give rise to mature mesenchymal cells such as adipocytes, osteoblasts, and chondrocytes, and to secrete a wide range of trophic and...
2015 / Lindolfo da Silva Meirelles, Tathiane Maistro Malta, Rodrigo Alexandre Panepucci, Wilson Araújo da Silva -
Data on AHR-dependent changes in the mitochondrial proteome in response to ,3,7,8-tetrachlorodibenzo-p-dioxin
Abstract The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that is the principal regulator of a cell׳s response to many polyaromatic hydrocarbons, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). To gain a better...
2016 / Hye Jin Hwang, Peter Dornbos, John J. LaPres -
New early Eocene vertebrate assemblage from western India reveals a mixed fauna of European and Gondwana affinities
Abstract The Ypresian Cambay Shale Formation at Vastan and Mangrol lignite mines in Gujarat, western India, has yielded a rich vertebrate fauna with numerous taxa of European affinities. Here we report a new, approximately contemporary vertebrate...
2016 / Thierry Smith, Kishor Kumar, Rajendra S. Rana, Annelise Folie, Floréal Solé, et al. -
Toxicological and biochemical responses of the earthworm Eisenia fetida to cyanobacteria toxins2017 / Qing Cao, Alan D. Steinman, Lei Yao, Liqiang Xie
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Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility2011 / Jian Zhao, Hui Wu, Melanie Khosravi, Huijuan Cui, Xiaoxia Qian, et al.
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Csl2, a novel chimeric bacteriophage lysin to fight infections caused by Streptococcus suis, an emerging zoonotic pathogen2017 / Roberto Vázquez, Mirian Domenech, Manuel Iglesias-Bexiga, Margarita Menéndez, Pedro García
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A novel Ala275Val mutation in factor X gene influences its structural compatibility and impairs intracellular trafficking and coagulant activity
Abstract Factor X (FX) deficiency is an autosomal recessive severe bleeding disorder. Here, we identified a novel homozygous missense mutation (p.Ala275Val) in the F10 gene in a patient with severe FX deficiency. The novel mutation was analyzed by...
2015 / Nannan Sun, Yongheng Chen, Hongling Peng, Yujiao Luo, Guangsen Zhang -
Complete genome sequence of Meiothermus ruber type strain (21T)2010 / Brian J Tindall, Johannes Sikorski, Susan Lucas, Eugene Goltsman, Alex Copeland, et al.
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Generation of KCL018 research grade human embryonic stem cell line carrying a mutation in the DMPK gene
Abstract The KCL018 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting one allele of the DMPK gene encoding the dystrophia myotonica protein kinase (2200 trinucleotide ...
2016 / Cristian Miere, Heema Hewitson, Liani Devito, Victoria Wood, Neli Kadeva, et al. -
Evaluating different DNA binding domains to modulate L1 ORF2p-driven site-specific retrotransposition events in human cells
Abstract DNA binding domains (DBDs) have been used with great success to impart targeting capabilities to a variety of proteins creating highly useful genomic tools. We evaluated the ability of five types of DBDs and strategies (AAV Rep proteins,...
2017 / Catherine M. Ade, Rebecca S. Derbes, Bradley J. Wagstaff, Sara B. Linker, Travis B. White, et al. -
A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease2017 / Liuhong Cai, Hao Bai, Vasiliki Mahairaki, Yongxing Gao, Chaoxia He, et al.
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N2 fixation and primary productivity in a red sea Halophila stipulacea meadow exposed to seasonality2017 / U. Cardini, N. van Hoytema, V. N. Bednarz, M. M. D. Al-Rshaidat, C. Wild
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Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production2017 / Angela Mogavero, Maria Valeria Maiorana, Susanna Zanutto, Luca Varinelli, Fabio Bozzi, et al.
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KV10.1 K+-channel plasma membrane discrete domain partitioning and its functional correlation in neurons
Abstract KV10.1 potassium channels are implicated in a variety of cellular processes including cell proliferation and tumour progression. Their expression in over 70% of human tumours makes them an attractive diagnostic and therapeutic target....
2013 / Aura M. Jiménez-Garduño, Miso Mitkovski, Ioannis K. Alexopoulos, Araceli Sánchez, Walter Stühmer, et al. -
Editorial: Nar Awards 20112011 /
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One stop shop: backbones trees for important phytopathogenic genera: I (2014)2014 / Kevin D. Hyde, R. Henrik Nilsson, S. Aisyah Alias, Hiran A. Ariyawansa, Jaime E. Blair, et al.
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Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations
Background & Aims Alagille syndrome is a genetic disorder characterized by cholestasis, ocular abnormalities, characteristic facial features, heart defects, and vertebral malformations. Most cases are associated with mutations in JAGGED1...
2017 / Emma R. Andersson, Indira V. Chivukula, Simona Hankeova, Marika Sjöqvist, Yat Long Tsoi, et al. -
Transcriptomics reveal an integrative role for maternal thyroid hormones during zebrafish embryogenesis2017 / Nadia Silva, Bruno Louro, Marlene Trindade, Deborah M. Power, Marco A. Campinho
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Land use not litter quality is a stronger driver of decomposition in hyperdiverse tropical forest2017 / Sabine Both, Dafydd M. O. Elias, Ully H. Kritzler, Nick J. Ostle, David Johnson