Biological sciences topic list of research papers
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Crystallization and first data collection of the putative transfer protein TraN from the Gram-positive conjugative plasmid pIP5012012 / Nikolaus Goessweiner-Mohr, Christian Fercher, Mohammad Yaser Abajy, Elisabeth Grohmann, Walter Keller
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Crosstalk between calpain activation and TGF-β1 augments collagen-I synthesis in pulmonary fibrosis
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease of unknown cause that typically leads to respiratory failure and death within 3–5years of diagnosis. TGF-β1 is considered a major profibrotic factor. However, TGF-β1...
2015 / Feng-Zhi Li, Peng-Cheng Cai, Lin-Jie Song, Li-Ling Zhou, Qian Zhang, et al. -
Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo
Summary Human intestinal organoids (HIOs) are a tissue culture model in which small intestine-like tissue is generated from pluripotent stem cells. By carrying out unsupervised hierarchical clustering of RNA-sequencing data, we demonstrate that HIOs ...
2015 / Stacy R. Finkbeiner, David R. Hill, Christopher H. Altheim, Priya H. Dedhia, Matthew J. Taylor, et al. -
A matter of identity — Phenotype and differentiation potential of human somatic stem cells
Abstract Human somatic stem cells with neural differentiation potential can be valuable for developing cell-based therapies, including treatment of birth-related defects, while avoiding issues associated with cell reprogramming. Precisely defining...
2015 / S.E.P. New, C. Alvarez-Gonzalez, B. Vagaska, S.G. Gomez, N.W. Bulstrode, et al. -
First phylogenetic analysis of the tribe Oligaphorurini (Collembola: Onychiuridae) inferred from morphological data, with implications for generic classification2017 / Grzegorz Paśnik, Wanda M. Weiner
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Using patient serum to epitope map soybean glycinins reveals common epitopes shared with many legumes and tree nuts
Abstract Soybean consumption is increasing in many Western diets; however, recent reviews suggest that the prevalence of soy allergy can be as high as 0.5% for the general population and up to 13% for children. The immunoglobulin-E (IgE) binding of...
2016 / Hanaa Saeed, Christine Gagnon, Elroy Cober, Steve Gleddie -
Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia
Summary Transcriptional deregulation plays a major role in acute myeloid leukemia, and therefore identification of epigenetic modifying enzymes essential for the maintenance of oncogenic transcription programs holds the key to better understanding...
2016 / Ngai Cheung, Tsz Kan Fung, Bernd B. Zeisig, Katie Holmes, Jayant K. Rane, et al. -
Deposition of 5-Methylcytosine on Enhancer RNAs Enables the Coactivator Function of PGC-1α
Summary The Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1α) is a transcriptional co-activator that plays a central role in adapted metabolic responses. PGC-1α is dynamically methylated and unmethylated at the residue...
2016 / Francesca Aguilo, SiDe Li, Natarajan Balasubramaniyan, Ana Sancho, Sabina Benko, et al. -
Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagy
Abstract We have recently discovered that soluble extracellular matrix constituents regulate autophagy via an outside-in signaling pathway. Decorin, a secreted proteoglycan, evokes autophagy in endothelial cells and mitophagy in breast carcinoma...
2015 / Maria A. Gubbiotti, Thomas Neill, Helena Frey, Liliana Schaefer, Renato V. Iozzo -
Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity
Summary Genome rearrangements, a hallmark of cancer, can result in gene fusions with oncogenic properties. Using DNA paired-end-tag (DNA-PET) whole-genome sequencing, we analyzed 15 gastric cancers (GCs) from Southeast Asians. Rearrangements were...
2015 / Fei Yao, Jaya P. Kausalya, Yee Yen Sia, Audrey S.M. Teo, Wah Heng Lee, et al. -
A perspective on the developmental toxicity of inhaled nanoparticles
Abstract This paper aimed to clarify whether maternal inhalation of engineered nanoparticles (NP) may constitute a hazard to pregnancy and fetal development, primarily based on experimental animal studies of NP and air pollution particles. Overall,...
2015 / Karin Sørig Hougaard, Luisa Campagnolo, Pascale Chavatte-Palmer, Anne Tarrade, Delphine Rousseau-Ralliard, et al. -
Genome-wide linkage and association analysis of rheumatoid arthritis in a Canadian population2009 / Zhi Wei, Mingyao Li
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Hydrographical parameters and phytoplankton assemblages along the Pondicherry–Nagapattinam coastal waters, southeast coast of India
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of < This article has been retracted at the request of the...
2015 / Pitchai Sampathkumar, Srinivasan Balakrishnan, Krishnamoorthy Kamalakannan, Rethinavelu Sankar, Lakshmanan Ramkumar, et al. -
Effects of biotic interactions on modeled species' distribution can be masked by environmental gradients2016 / William Godsoe, Janet Franklin, F. Guillaume Blanchet
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Evaluating landowner-based beaver relocation as a tool to restore salmon habitat
Abstract Relocating American beavers (Castor canadensis) from unwanted sites to desirable sites (i.e., where damage exceeds stakeholder capacity) has been posited as a method to enhance in-stream habitat for salmonids in the Pacific Northwest region ...
2015 / V.M. Petro, J.D. Taylor, D.M. Sanchez -
Functional and Morphological Improvement of Dystrophic Muscle by Interleukin 6 Receptor Blockade
Abstract The anti-inflammatory agents glucocorticoids (GC) are the only available treatment for Duchenne muscular dystrophy (DMD). However, long-term GC treatment causes muscle atrophy and wasting. Thus, targeting specific mediator of inflammatory...
2015 / Laura Pelosi, Maria Grazia Berardinelli, Loredana De Pasquale, Carmine Nicoletti, Adele D'Amico, et al. -
Amelioration of Hyperbilirubinemia in Gunn Rats after Transplantation of Human Induced Pluripotent Stem Cell-Derived Hepatocytes
Summary Hepatocyte transplantation has the potential to cure inherited liver diseases, but its application is impeded by a scarcity of donor livers. Therefore, we explored whether transplantation of hepatocyte-like cells (iHeps) differentiated from...
2015 / Yong Chen, Yanfeng Li, Xia Wang, Wei Zhang, Vanessa Sauer, et al. -
Glutamate presynaptic vesicular transporter and postsynaptic receptor levels correlate with spatial memory status in aging rat models
Abstract In humans, memory capacities are generally affected with aging, even without any reported neurologic disorders. The mechanisms behind cognitive decline are not well understood. We studied here whether postsynaptic glutamate receptor and...
2014 / Caroline Ménard, Rémi Quirion, Erika Vigneault, Sylvain Bouchard, Guylaine Ferland, et al. -
Adenylyl cyclase mRNA localizes to the posterior of polarized DICTYOSTELIUM cells during chemotaxis2017 / Satarupa Das, Joshua M. Parker, Can Guven, Weiye Wang, Paul W. Kriebel, et al.
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Next generation sequencing on patients with LGMD and nonspecific myopathies: Findings associated with ANO5 mutations
Abstract We studied 786 undiagnosed patients with LGMD or nonspecific myopathic features to investigate the role of ANO5 mutations in limb-girdle muscular dystrophies (LGMDs) and in nonspecific myopathies using the next generation sequencing (NGS)...
2015 / Marco Savarese, Giuseppina Di Fruscio, Giorgio Tasca, Lucia Ruggiero, Sandra Janssens, et al.