Basic medicine topic list of research papers
-
Exercise and its role in gestational diabetes mellitus
Abstract Gestational diabetes mellitus (GDM) refers to diabetes diagnosed in the second or third trimester of pregnancy that is not clearly either type 1 or type 2 diabetes. GDM is a common medical complication in pregnancy that has been rapidly...
2016 / Chen Wang, Kym Janese Guelfi, Hui-Xia Yang -
Identifying Predictors of Central Sleep Apnea/Cheyne-Stokes Breathing in Chronic Heart Failure: a Pathophysiological Approach2017 / Aneliya I. Draganova, Kiril V. Terziyski, Stefan S. Kostianev
-
Osteopontin attenuates acute gastrointestinal graft-versus-host disease by preventing apoptosis of intestinal epithelial cells
Abstract Background and aims Acute graft-versus-host disease (GVHD) is a major complication after allogeneic hematopoietic stem cell transplantation, which often targets gastrointestinal (GI) tract. Osteopontin (OPN) plays an...
2017 / Kentaro Kawakami, Naoki Minami, Minoru Matsuura, Tomoya Iida, Takahiko Toyonaga, et al. -
Mitochondrial-Shaping Proteins in Cardiac Health and Disease – the Long and the Short of It!2017 / Sang-Bing Ong, Siavash Beikoghli Kalkhoran, Sauri Hernández-Reséndiz, Parisa Samangouei, Sang-Ging Ong, et al.
-
Comparison of the acute inhibitory effects of Tetrodotoxin (TTX) in rat and human neuronal networks for risk assessment purposes
Abstract Tetrodotoxin (TTX) is an extremely toxic marine neurotoxin. TTX inhibits voltage-gated sodium channels, resulting in a potentially lethal inhibition of neurotransmission. Despite numerous intoxications in Asia and Europe, limited (human)...
2017 / Emma E.J. Kasteel, Remco H.S. Westerink -
Regulation of cardiac CACNB2 by microRNA-499: Potential role in atrial fibrillation
Abstract The L-type calcium channel (LTCC) is one of the major ion channels that are known to be associated with the electrical remodeling of atrial fibrillation (AF). In AF, there is significant downregulation of the LTCC, but the underlying...
2017 / Tian-You Ling, Xiao-Li Wang, Qiang Chai, Tong Lu, John M. Stulak, et al. -
Renal Denervation Reduces Pulmonary Vascular Remodeling and Right Ventricular Diastolic Stiffness in Experimental Pulmonary Hypertension
Summary Neurohormonal overactivation plays an important role in pulmonary hypertension (PH). In this context, renal denervation, which aims to inhibit the neurohormonal systems, may be a promising adjunct therapy in PH. In this proof-of-concept...
2017 / Denielli da Silva Gonçalves Bos, Chris Happé, Ingrid Schalij, Wioletta Pijacka, Julian F.R. Paton, et al. -
Sodium channel biophysics, late sodium current and genetic arrhythmic syndromes2017 / Karan R. Chadda, Kamalan Jeevaratnam, Ming Lei, Christopher L.-H. Huang
-
Ghrelin and hormonal markers under exercise training in patients with heart failure with preserved ejection fraction: results from the Ex-DHF pilot study2016 / Tobias Daniel Trippel, Volker Holzendorf, Martin Halle, Götz Gelbrich, Kathleen Nolte, et al.
-
Assessing sleepiness and cataplexy in children and adolescents with narcolepsy: a review of current patient-reported measures
Abstract Objective The objective of this study was to review patient-reported outcome measures assessing excessive daytime sleepiness (EDS) or cataplexy in children or adolescents to determine their usefulness and limitations in...
2017 / Khadra Benmedjahed, Y. Grace Wang, Jérémy Lambert, Christopher Evans, Steve Hwang, et al. -
Serially measured circulating miR-22-3p is a biomarker for adverse clinical outcome in patients with chronic heart failure: The Bio-SHiFT study
Abstract Background Several studies have suggested circulating microRNAs (miRs) are associated with heart failure, but these studies were small, and limited to single miR measurements. We examined 7 miRs which...
2017 / Nick van Boven, K. Martijn Akkerhuis, Sharda S. Anroedh, Dimitris Rizopoulos, Yigal Pinto, et al. -
Long-term administration of pyridostigmine attenuates pressure overload-induced cardiac hypertrophy by inhibiting calcineurin signalling2017 / Yi Lu, Ming Zhao, Jin-Jun Liu, Xi He, Xiao-Jiang Yu, et al.
-
An Oral Selective Alpha-1A Adrenergic Receptor Agonist Prevents Doxorubicin Cardiotoxicity
Summary Alpha-1 adrenergic receptors (α1-ARs) play adaptive and protective roles in the heart. Dabuzalgron is an oral selective α1A-AR agonist that was well tolerated in multiple clinical trials of treatment for urinary incontinence, but has never...
2017 / Ju Youn Beak, Wei Huang, Joel S. Parker, Sean T. Hicks, Cam Patterson, et al. -
Recent Advances in Biomarker Discovery — from Serum to Imaging-based Biomarkers for a Complex Assessment of Heart Failure Patients2016 / Andreea-Luciana Chiotoroiu, Corneliu-Florin Buicu, Claudiu Neagu, Theodora Benedek
-
The effects of short-term omission of daily medication on the pathophysiology of heart failure2017 / Silviu Dovancescu, Pierpaolo Pellicori, Thato Mabote, Azam Torabi, Andrew L. Clark, et al.
-
Apolipoprotein E mimetic peptide, CN-105, improves outcomes in ischemic stroke2017 / Tian Ming Tu, Brad J. Kolls, Erik J. Soderblom, Viviana Cantillana, Paul Durham Ferrell, et al.
-
Nigella sativa protects against isoproterenol-induced myocardial infarction by alleviating oxidative stress, biochemical alterations and histological damage
Abstract Objective To evaluate the cardioprotective effect of Nigella sativa L. (N. sativa) in isoproterenol-induced myocardial infarction (MI). Methods Groups...
2017 / Md. Quamrul Hassan, Mohd. Akhtar, Sayeed Ahmed, Aftab Ahmad, Abul Kalam Najmi -
Human Second Window Pre-Conditioning and Post-Conditioning by Nitrite Is Influenced by a Common Polymorphism in Mitochondrial Aldehyde Dehydrogenase
Summary Pre-conditioning is an exciting physiological phenomenon that, despite great efforts, has so far resisted translation to mainstream clinical medicine. Many potential triggers (e.g., ischemia of the organ in question or a remote organ, many...
2017 / Julian O.M. Ormerod, Jonathan D.W. Evans, Hussain Contractor, Matteo Beretta, Sayqa Arif, et al. -
Novel Antiarrhythmic Drugs for the Treatment of Atrial Fibrillation: Current Perspective2012 / Haruaki Nakaya
-
Non-Coding RNAs Including miRNAs and lncRNAs in Cardiovascular Biology and Disease2014 / Masaharu Kataoka, Da-Zhi Wang