Basic medicine topic list of research papers
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The blocking of angiotensin II type 1 receptor and RhoA/Rho kinase activity in hypertensive patients: Effect of olmesartan medoxomil and implication with cardiovascular-renal remodeling2015 / V. Ravarotto, E. Pagnin, G. Maiolino, A. Fragasso, G. Carraro, et al.
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Sudden cardiac death in ischemic heart disease. Pathophysiology and risk stratification2015 / Nabil El-Sherif
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Recombinant human soluble thrombomodulin improved lipopolysaccharide/d-galactosamine-induced acute liver failure in mice
Abstract The effect of recombinant human soluble thrombomodulin (TM-α) on acute liver failure (ALF) is unclear, and we elucidated the effect of TM-α in lipopolysaccharide (LPS)/d-galactosamine (GalN)-induced ALF in mice. Placebo (saline) or TM-α...
2015 / Wataru Osumi, Denan Jin, Yoshiro Imai, Keitaro Tashiro, Zhong-Lian Li, et al. -
CD40 in coronary artery disease: a matter of macrophages?2016 / Matthijs F. Jansen, Maurits R. Hollander, Niels van Royen, Anton J. Horrevoets, Esther Lutgens
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The emerging role of Toll-like receptor 4 in myocardial inflammation2016 / Y Yang, J Lv, S Jiang, Z Ma, D Wang, et al.
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Comparing the impact of an acute exercise bout on plasma amino acid composition, intraerythrocytic Ca2+ handling, and red cell function in athletes and untrained subjects
Abstract The N-methyl d-aspartate receptors (NMDARs) mediating Ca2+ uptake upon stimulation with glutamate and glycine were recently discovered in red blood cells (RBC) of healthy humans. Activation of these receptors with agonists triggered...
2016 / Asya Makhro, Thomas Haider, Jue Wang, Nikolay Bogdanov, Patrick Steffen, et al. -
Cardiosphere-Derived Cells Reverse Heart Failure With Preserved Ejection Fraction in Rats by Decreasing Fibrosis and Inflammation
Summary The pathogenesis of heart failure with a preserved ejection fraction (HFpEF) is unclear. Myocardial fibrosis, inflammation, and cardiac hypertrophy have been suggested to contribute to the pathogenesis of HFpEF. Cardiosphere-derived cells...
2016 / Romain Gallet, Geoffrey de Couto, Eli Simsolo, Jackelyn Valle, Baiming Sun, et al. -
The Pathogenesis of Resection-Associated Intestinal Adaptation
After massive small-bowel resection, the remnant bowel compensates by a process termed adaptation. Adaptation is characterized by villus elongation and crypt deepening, which increases the capacity for absorption and digestion per unit length. The...
2016 / Brad W. Warner -
Brief Myocardial Ischemia Produces Cardiac Troponin I Release and Focal Myocyte Apoptosis in the Absence of Pathological Infarction in Swine
Summary In a porcine model of brief ischemia leading to reversible stunning in the absence of tissue necrosis, we demonstrated delayed release of cardiac troponin I (cTnI) that exceeded the 99th percentile for normal animals 60 min after reperfusion ...
2017 / Brian R. Weil, Rebeccah F. Young, Xiaomeng Shen, Gen Suzuki, Jun Qu, et al. -
Platelet Function and Fibrinolytic Activity in Hypertensive and Normotensive Sleep Apnea Patients2017 /
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Enhanced Calvarial Bone Healing in CD11c-TLR4−/− and MyD88−/− Mice2017 / Dan Wang, Gwen M. Taylor, James R. Gilbert, Joseph E. Losee, Chhinder P. Sodhi, et al.
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Cardiac regenerative medicine: At the crossroad of microRNA function and biotechnology
Abstract There is an urgent need to develop new therapeutic strategies to stimulate cardiac repair after damage, such as myocardial infarction. Already for more than a century scientist are intrigued by studying the regenerative capacity of the...
2017 / Andrea Raso, Ellen Dirkx -
Cardiac Myosin Binding Protein-C Autoantibodies Are Potential Early Indicators of Cardiac Dysfunction and Patient Outcome in Acute Coronary Syndrome
Summary The degradation and release of cardiac myosin binding protein-C (cMyBP-C) upon cardiac damage may stimulate an inflammatory response and autoantibody (AAb) production. We determined whether the presence of cMyBP-C-AAbs associated with...
2017 / Thomas L. Lynch, Diederik W.D. Kuster, Beverly Gonzalez, Neelam Balasubramanian, Nandini Nair, et al. -
Cardiac Biomarkers and the Diagnosis of Myocardial Infarction in Women2017 / Anoop S. V. Shah, Amy V. Ferry, Nicholas L. Mills
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Successful catheter ablation of recipient left ventricular tachycardia 26 years after heterotopic heart transplantation2017 / Mikael Laredo, Shaida Varnous, Pauline Balagny, Pascal Leprince, Françoise Hidden-Lucet, et al.
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Mesenchymal stem cell therapy for doxorubicin cardiomyopathy: hopes and fears2015 / Fernando Ezquer, Jaime Gutiérrez, Marcelo Ezquer, Christian Caglevic, Helio C Salgado, et al.
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Ischemic postconditioning of the isolated human myocardium: Role of the applied protocol
Abstract Background Ischemic postconditioning (IPostC), has been proposed as a useful approach to reduce infarct size in all species, but its clinical utility remains unclear. ...
2015 / Kelly Casós, María-Llanos Pérez, Arnau Blasco-Lucas, Gemma Ferrer-Curriu, Juan Manuel Gracia-Baena, et al. -
Maturation status of sarcomere structure and function in human iPSC-derived cardiac myocytes
Abstract Human heart failure due to myocardial infarction is a major health concern. The paucity of organs for transplantation limits curative approaches for the diseased and failing adult heart. Human induced pluripotent stem cell-derived cardiac...
2015 / Fikru B. Bedada, Matthew Wheelwright, Joseph M. Metzger -
Mechano-Electric Heterogeneity Of The Myocardium As A Paradigm Of Its Function
Abstract Myocardial heterogeneity is well appreciated and widely documented, from sub-cellular to organ levels. This paper reviews significant achievements of the group, led by Professor Vladimir S. Markhasin, Russia, who was one of the pioneers in...
2015 / Olga Solovyova, Leonid B. Katsnelson, Peter Kohl, Alexander V. Panfilov, Andrey K. Tsaturyan, et al. -
Hemodynamic effects of Purkinje potential pacing in the left ventricular endocardium in patients with advanced heart failure
Abstract Background Various difficulties can occur in patients who undergo cardiac resynchronization therapy for drug-refractory heart failure with respect to placement of the left ventricular (LV) lead, because of anatomical...
2015 / Mamoru Hamaoka, Takanao Mine, Takeshi Kodani, Hideyuki Kishima, Masataka Mitsuno, et al.