Basic medicine topic list of research papers
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Redox signaling in cardiovascular pathophysiology: A focus on hydrogen peroxide and vascular smooth muscle cells
Abstract Oxidative stress represents excessive intracellular levels of reactive oxygen species (ROS), which plays a major role in the pathogenesis of cardiovascular disease. Besides having a critical impact on the development and progression of...
2016 / Chang Hyun Byon, Jack M. Heath, Yabing Chen -
Ambulatory Blood Pressure in Chronic Kidney Disease: Ready for Prime Time?
Hypertension is common in patients with chronic kidney disease (CKD) and is the most important modifiable risk factor for CKD progression and adverse cardiovascular events in these patients. Diagnosis and successful management of hypertension are critically...
2016 / Manuel T. Velasquez, Srinivasan Beddhu, Ehsan Nobakht, Mahboob Rahman, Dominic S. Raj -
No benefit of additional treatment with exenatide in patients with an acute myocardial infarction
Abstract Objectives This double blinded, placebo controlled randomized clinical trial studies the effect of exenatide on myocardial infarct size. The glucagon-like peptide-1 receptor agonist exenatide has possible cardioprotective...
2016 / Sebastiaan T. Roos, Leo Timmers, Paul S. Biesbroek, Robin Nijveldt, Otto Kamp, et al. -
Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways2016 / Lisa A. Lesniewski, Douglas R. Seals, Ashley E. Walker, Grant D. Henson, Mark W. Blimline, et al.
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Highly purified eicosapentaenoic acid ameliorates cardiac injury and adipose tissue inflammation in a rat model of metabolic syndrome2016 / S. Ito, Y. Sano, K. Nagasawa, N. Matsuura, Y. Yamada, et al.
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Tbx18 and the generation of a biological pacemaker. Are we there yet?2016 / Thomas Brand
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Factors associated with short sleep duration in adolescents
Abstract Objective This study aimed to investigate the prevalence and factors associated with short sleep duration in adolescents from Maravilha – Santa Catarina (SC), southern Brazil. ...
2015 / Érico Pereira Gomes Felden, Douglas Filipin, Diego Grasel Barbosa, Rubian Diego Andrade, Carolina Meyer, et al. -
Modulation of ambient temperature promotes inflammation and initiates atherosclerosis in wild type C57BL/6 mice
Abstract Objectives Obesity and obesity-associated inflammation is central to a variety of end-organ sequelae including atherosclerosis, a leading cause of death worldwide. Although mouse models have provided important insights...
2016 / Daniel A. Giles, Bhama Ramkhelawon, Elizabeth M. Donelan, Traci E. Stankiewicz, Susan B. Hutchison, et al. -
Macrophages of genetically characterized familial hypercholesterolaemia patients show up-regulation of LDL-receptor-related proteins2016 / Rafael Escate, Teresa Padro, Maria Borrell-Pages, Rosa Suades, Rosa Aledo, et al.
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Predictive value of serum Inhibin-B levels as an indicator of the presence of testicular spermatozoa in non-obstructive azoospermia
Abstract Introduction: Inhibin-B is glycoproteins of the transforming growth factor-β superfamily, is produced almost exclusively by the Sertoli cells and has been proposed as direct markers of their function and indirect...
2016 / Marwan Alhalabi -
From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research”2016 / Hector A. Cabrera-Fuentes, Julian Aragones, Jürgen Bernhagen, Andreas Boening, William A. Boisvert, et al.
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Prediction of 1-year clinical outcomes using the SYNTAX score in patients with prior heart failure undergoing percutaneous coronary intervention: sub-analysis of the SHINANO registry2016 / Masatoshi Minamisawa, Takashi Miura, Hirohiko Motoki, Hideki Kobayashi, Masanori Kobayashi, et al.
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Randomized Comparison of Allogeneic Vs. Autologous Mesenchymal Stem Cells for Non-lschemic Dilated Cardiomyopathy: POSEIDON-DCM Trial
Abstract Background Although human mesenchymal stem cells (hMSCs) have been tested in ischemic cardiomyopathy, few studies exist in chronic nonischemic dilated cardiomyopathy (NIDCM). ...
2016 / Joshua M. Hare, Darcy L. DiFede, Angela M. Castellanos, Victoria Florea, Ana M. Landin, et al. -
Left ventricular ejection fraction recovery in patients with heart failure treated with intravenous iron: a pilot study2016 / Julio Núñez, José Vicente Monmeneu, Anna Mollar, Eduardo Núñez, Vicent Bodí, et al.
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Mass spectrometry profiling of oxysterols in human sperm identifies 25-hydroxycholesterol as a marker of sperm function
Abstract Cholesterol is a main lipid component of sperm cell that is essential for sperm membrane fluidity, capacitation, and acrosomal reaction. Recent data obtained in bovine sperm showed that sperm capacitation is associated to the formation of...
2016 / Chiara Zerbinati, Luisa Caponecchia, Rosa Puca, Marco Ciacciarelli, Pietro Salacone, et al. -
Renal Replacement Therapy in Patients with Heart and Kidney Failure2016 / Dimitrios S Goumenos, Evangelos Papachristou, Marios Papasotiriou
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Assessment of functional capacity and sleep quality of patients with chronic heart failure
Abstract Background Adequate sleep improves physical and mental alertness. However, there is a dearth of empirical data on functional capacity (FC) and sleep quality (SpQ) in patients with chronic heart failure (CHF). ...
2016 / Taofeek O. Awotidebe, Victor O. Adeyeye, Rufus A. Adedoyin, Suraj A. Ogunyemi, Kayode I. Oke, et al. -
Modified Atkins diet induces subacute selective ragged‐red‐fiber lysis in mitochondrial myopathy patients2016 / Sofia Ahola, Mari Auranen, Pirjo Isohanni, Satu Niemisalo, Niina Urho, et al.
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Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart
Summary This study sought to investigate the effects of mechanical unloading on myocardial energetics and the metabolic perturbation of heart failure (HF) in an effort to identify potential new therapeutic targets that could enhance the...
2016 / Nikolaos A. Diakos, Sutip Navankasattusas, E. Dale Abel, Jared Rutter, Lauren McCreath, et al. -
Electrophysiological mechanisms of long and short QT syndromes
Abstract The QT interval on the human electrocardiogram is normally in the order of 450ms, and reflects the summated durations of action potential (AP) depolarization and repolarization of ventricular myocytes. Both prolongation and shortening in...
2016 / Gary Tse, Yin Wah Fiona Chan, Wendy Keung, Bryan P Yan