Chemical sciences topic list of research papers
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Online analysis of oxygen inside silicon-glass microreactors with integrated optical sensors
Abstract A powerful online analysis set-up for oxygen measurements within microfluidic devices is presented. It features integration of optical oxygen sensors into microreactors, which enables contactless, accurate and inexpensive readout using...
2016 / Josef Ehgartner, Philipp Sulzer, Tobias Burger, Alice Kasjanow, Dominique Bouwes, et al. -
Intrinsic immunogenicity of rapidly-degradable polymers evolves during degradation
Abstract Recent studies reveal many biomaterial vaccine carriers are able to activate immunostimulatory pathways, even in the absence of other immune signals. How the changing properties of polymers during biodegradation impact this intrinsic...
2015 / James I. Andorko, Krystina L. Hess, Kevin G. Pineault, Christopher M. Jewell -
The optimization of Marasmius androsaceus submerged fermentation conditions in five-liter fermentor
Abstract Using desirability function, four indexes including mycelium dry weight, intracellular polysaccharide, adenosine and mannitol yield were uniformed into one expected value (Da) which further served as the assessment criteria. In our present...
2015 / Fanxin Meng, Gaoyang Xing, Yutong Li, Jia Song, Yanzhen Wang, et al. -
Carbon nanotubes' surface chemistry determines their potency as vaccine nanocarriers in vitro and in vivo
Abstract Carbon nanotubes (CNTs) have shown marked capabilities in enhancing antigen delivery to antigen presenting cells. However, proper understanding of how altering the physical properties of CNTs may influence antigen uptake by antigen...
2016 / Hatem A.F.M. Hassan, Lesley Smyth, Noelia Rubio, Kulachelvy Ratnasothy, Julie T.-W. Wang, et al. -
Derivatization of estrogens enhances specificity and sensitivity of analysis of human plasma and serum by liquid chromatography tandem mass spectrometry
Abstract Estrogens circulate at concentrations less than 20pg/mL in men and postmenopausal women, presenting analytical challenges. Quantitation by immunoassay is unreliable at these low concentrations. Liquid chromatography tandem mass spectrometry ...
2015 / Abdullah M.M. Faqehi, Diego F. Cobice, Gregorio Naredo, Tracy C.S. Mak, Rita Upreti, et al. -
Application of Gap-Constraints Given Sequential Frequent Pattern Mining for Protein Function Prediction
Abstract Objectives Predicting protein function from the protein–protein interaction network is challenging due to its complexity and huge scale of protein interaction process along with inconsistent pattern. Previously proposed...
2015 / Hyeon Ah Park, Taewook Kim, Meijing Li, Ho Sun Shon, Jeong Seok Park, et al. -
Initial Carbon-Carbon Bond Formation during the Early Stages of the Methanol-to-Olefin Process Proven by Zeolite-Trapped Acetate and Methyl Acetate2016 / Abhishek Dutta Chowdhury, Klaartje Houben, Gareth T. Whiting, Mohamed Mokhtar, Abdullah M. Asiri, et al.
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Logical design of anti-prion agents using NAGARA
Abstract To accelerate the logical drug design procedure, we created the program “NAGARA,” a plugin for PyMOL, and applied it to the discovery of small compounds called medical chaperones (MCs) that stabilize the cellular form of a prion protein...
2015 / Biao Ma, Keiichi Yamaguchi, Mayuko Fukuoka, Kazuo Kuwata -
Label-free electrochemical impedance biosensor to detect human interleukin-8 in serum with sub-pg/ml sensitivity
Abstract Biosensors with high sensitivity and short time-to-result that are capable of detecting biomarkers in body fluids such as serum are an important prerequisite for early diagnostics in modern healthcare provision. Here, we report the...
2016 / R. Sharma, S.E. Deacon, D. Nowak, S.E. George, M.P. Szymonik, et al. -
Study on the effect of the degree of grafting on the performance of polyethylene-based anion exchange membrane for fuel cell application
Abstract Alkaline anion exchange membranes (AAEM) are fabricated using polyethylene as the base polymer offering a low cost AAEM. This study focuses on the synthesis and characterisation of AAEM with controlled degree of grafting (DOG) and...
2015 / Richard Espiritu, Mohamed Mamlouk, Keith Scott -
A new lysine derived glyoxal inhibitor of trypsin, its properties and utilization for studying the stabilization of tetrahedral adducts by trypsin
Abstract New trypsin inhibitors Z-Lys-COCHO and Z-Lys-H have been synthesised. K i values for Z-Lys-COCHO, Z-Lys-COOH, Z-Lys-H and Z-Arg-COOH have been determined. The glyoxal group (–COCHO) of Z-Lys-COCHO increases binding ~300 ...
2016 / Jennifer A. Cleary, J. Paul G. Malthouse -
Controlled copolymerization of the functional 5-membered lactone monomer, α-bromo-γ-butyrolactone, via selective organocatalysis
Abstract The selective nature of organic catalysts has been exploited to synthesize copolymers of the functional monomer, α-bromo-γ-butyrolactone (αBrγBL), with trimethylene carbonate (TMC), 2-allyloxymethyl-2-ethyl-trimethylene carbonate (AOMEC)...
2016 / Jenny Undin, Peter Olsén, Jamie Godfrey, Karin Odelius, Ann-Christine Albertsson -
Combined structure- and ligand-based virtual screening to evaluate caulerpin analogs with potential inhibitory activity against monoamine oxidase B2015 / Vitor Prates Lorenzo, José Maria Barbosa Filho, Luciana Scotti, Marcus Tullius Scotti
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Physio-chemical assessment of beauty leaf (Calophyllum inophyllum) as second-generation biodiesel feedstock
Abstract Recently, second-generation (non-vegetable oil) feedstocks for biodiesel production are receiving significant attention due to the cost and social effects connected with utilising food products for the production of energy products. The...
2015 / M.I. Jahirul, R.J. Brown, W. Senadeera, N. Ashwath, M.G. Rasul, et al. -
Pharmacokinetic and pharmacodynamic study of triptolide-loaded liposome hydrogel patch under microneedles on rats with collagen-induced arthritis
Abstract Triptolide (TP), a major active component of Tripterygium wilfordii Hook.F. (TWHF), is used to treat rheumatoid arthritis (RA). However, it has a narrow therapeutic window due to its serious toxicities. To increase the therapeutic index, a...
2015 / Gui Chen, Baohua Hao, Dahong Ju, Meijie Liu, Hongyan Zhao, et al. -
Tracking changes in the optical properties and molecular composition of dissolved organic matter during drinking water production
Abstract Absorbance, 3D fluorescence and ultrahigh resolution electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI-FT-ICR-MS) were used to explain patterns in the removal of chromophoric and fluorescent dissolved...
2015 / E.E. Lavonen, D.N. Kothawala, L.J. Tranvik, M. Gonsior, P. Schmitt-Kopplin, et al. -
The biophysical properties of ethanolamine plasmalogens revealed by atomistic molecular dynamics simulations
Abstract Given the importance of plasmalogens in cellular membranes and neurodegenerative diseases, a better understanding of how plasmalogens affect the lipid membrane properties is needed. Here we carried out molecular dynamics simulations to...
2015 / Tomasz Rog, Artturi Koivuniemi -
Effect of filler and application mode on micro-shear bond strength of etch-and-rinse adhesive systems
Abstract Objective To evaluate the effect of the application modes and the presence of filler of etch-and-rinse adhesive systems on the micro-shear bond strength test (μSBS) to bovine dentin. ...
2015 / Ceci Nunes Carvalho, Carlos Eduardo Francci, José Ferreira Costa, José Bauer -
In vitro alpha glucosidase inhibition and free-radical scavenging activity of propolis from Thai stingless bees in mangosteen orchard2015 / Boonyadist Vongsak, Sumet Kongkiatpaiboon, Sunan Jaisamut, Sasipawan Machana, Chamnan Pattarapanich
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Conformational analysis of small organic molecules using NOE and RDC data: A discussion of strychnine and α-methylene-γ-butyrolactone
Abstract To understand the properties and/or reactivity of an organic molecule, an understanding of its three-dimensional structure is necessary. Simultaneous determination of configuration and conformation often poses a daunting challenge. Thus,...
2015 / Andreas Kolmer, Luke J. Edwards, Ilya Kuprov, Christina M. Thiele