Biological sciences topic list of research papers
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MECP2e1 isoform mutation affects the form and function of neurons derived from Rett syndrome patient iPS cells
Abstract MECP2 mutations cause the X-linked neurodevelopmental disorder Rett Syndrome (RTT) by consistently altering the protein encoded by the MECP2e1 alternative transcript. While mutations that simultaneously affect both...
2015 / Ugljesa Djuric, Aaron Y.L. Cheung, Wenbo Zhang, Rebecca S. Mok, Wesley Lai, et al. -
Assessing the distribution and habitat use of four felid species in Bukit Barisan Selatan National Park, Sumatra, Indonesia
Abstract There have been few targeted studies of small felids in Sumatra and there is little information on their ecology. As a result there are no specific management plans for the species on Sumatra. We examined data from a long-term camera...
2014 / Jennifer L. McCarthy, Hariyo T. Wibisono, Kyle P. McCarthy, Todd K. Fuller, Noviar Andayani -
Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: Implications for Age-related Macular Degeneration
Abstract Oxidative stress has a critical role in the pathogenesis of Age-related Macular Degeneration (AMD), a multifactorial disease that includes age, gene variants of complement regulatory proteins and smoking as the main risk factors....
2015 / Mariela C. Marazita, Andrea Dugour, Melisa D. Marquioni-Ramella, Juan M. Figueroa, Angela M. Suburo -
Low and variable ecosystem calcification in a coral reef lagoon under natural acidification2017 / Kathryn E. F. Shamberger, Steven J. Lentz, Anne L. Cohen
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Plant organellar DNA primase-helicase synthesizes RNA primers for organellar DNA polymerases using a unique recognition sequence2017 / Antolín Peralta-Castro, Noe Baruch-Torres, Luis G. Brieba
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IRGM in autophagy and viral infections2013 / Denitsa S. Petkova, Christophe Viret, Mathias Faure
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The Q223R polymorphism in the leptin receptor associates with objectively measured light physical activity in free-living Japanese
Abstract Physical activity (PA) is associated with reductions in the risk of all-cause mortality and in the prevalence of cardiovascular disease and stroke. Nevertheless, a large proportion of the general population may not be sufficiently active....
2014 / Haruka Murakami, Motoyuki Iemitsu, Noriyuki Fuku, Kiyoshi Sanada, Yuko Gando, et al. -
Data-driven modelling of a gene regulatory network for cell fate decisions in the growing limb bud2015 / M. Uzkudun, L. Marcon, J. Sharpe
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Bis(2,6-diaminopyridin-1-ium) hexaaquacobalt(II) disulfate dihydrate2010 / Mohammad T. M. Al-Dajani, Habibah A Wahab, Nornisah Mohamed, Jia Hao Goh, Hoong-Kun Fun
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Arbuscular mycorrhizal fungi promote coexistence and niche divergence of sympatric palm species on a remote oceanic island2017 / Owen G. Osborne, Rishi De-Kayne, Martin I. Bidartondo, Ian Hutton, William J. Baker, et al.
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Correlating rrs and eis promoter mutations in clinical isolates of Mycobacterium tuberculosis with phenotypic susceptibility levels to the second-line injectables
Abstract Objective/background The in vitro drug-susceptibility testing of Mycobacterium tuberculosis reports isolates as resistant or susceptible on the basis of single critical concentrations. It is evident that drug resistance in ...
2015 / Priti Kambli, Kanchan Ajbani, Chaitali Nikam, Meeta Sadani, Anjali Shetty, et al. -
Analysis of 36 Y-STR marker units including a concordance study among 2085 Dutch males
Abstract The genotypes of 36 Y-chromosomal short tandem repeat (Y-STR) marker units were analysed in a Dutch population sample of 2085 males. Profiling results were compared for several partially overlapping kits, i.e. PowerPlex Y, Yfiler, PowerPlex ...
2014 / Antoinette A. Westen, Thirsa Kraaijenbrink, Lindy Clarisse, Laurens J.W. Grol, Patricia Willemse, et al. -
Genotypic and bioinformatic evaluation of the alpha-l-iduronidase gene and protein in patients with mucopolysaccharidosis type I from Colombia, Ecuador and Peru
Abstract Mucopolysaccharidosis type I (MPSI) is a rare autosomal recessive disorder caused by mutations in the gene encoding the lysosomal enzyme α-l-iduronidase (IDUA), which is instrumental in the hydrolysis of the glycosaminoglycans, dermatan and ...
2014 / Tatiana Pineda, Sulie Marie, Janneth Gonzalez, Ana L. García, Amparo Acosta, et al. -
The multi-dimensional roles of astrocytes in ALS
Abstract Despite significant progress in understanding the molecular and genetic aspects of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease characterized by the progressive loss of motor neurons, the precise and comprehensive...
2017 / Koji Yamanaka, Okiru Komine -
The TREAT-NMD DMD Global Database: Analysis of More than 7,000 Duchenne Muscular Dystrophy Mutations2015 / Catherine L. Bladen, David Salgado, Soledad Monges, Maria E. Foncuberta, Kyriaki Kekou, et al.
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Suppression of GRK2 expression reduces endothelial dysfunction by restoring glucose homeostasis2017 / Kumiko Taguchi, Mari Hida, Mami Hasegawa, Haruka Narimatsu, Takayuki Matsumoto, et al.
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Plasmodium falciparum Calcium-Dependent Protein Kinase 2 Is Critical for Male Gametocyte Exflagellation but Not Essential for Asexual Proliferation2017 / Abhisheka Bansal, Alvaro Molina-Cruz, Joseph Brzostowski, Jianbing Mu, Louis H. Miller
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Genetic accommodation via modified endocrine signalling explains phenotypic divergence among spadefoot toad species2017 / Saurabh S. Kulkarni, Robert J. Denver, Ivan Gomez-Mestre, Daniel R. Buchholz
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Cell Death Pathways: a Novel Therapeutic Approach for Neuroscientists2017 / G. Morris, A. J. Walker, M. Berk, M. Maes, B. K. Puri
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Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? I. Reports of individual databases presented at an EURL ECVAM Workshop
Abstract Positive results in the Ames test correlate well with carcinogenic potential in rodents. This correlation is not perfect because mutations are only one of many stages in tumour development. Also, situations can be envisaged where the...
2014 / David Kirkland, Errol Zeiger, Federica Madia, Nigel Gooderham, Peter Kasper, et al.