Biological sciences topic list of research papers
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Methylmalonyl-coA epimerase deficiency: A new case, with an acute metabolic presentation and an intronic splicing mutation in the MCEE gene
Abstract Methylmalonyl-coA epimerase (MCE) follows propionyl-coA carboxylase and precedes methylmalonyl-coA mutase in the pathway converting propionyl-coA to succinyl-coA. MCE deficiency has previously been described in six patients, one presenting...
2016 / Paula J. Waters, Fanny Thuriot, Joe T.R. Clarke, Serge Gravel, David Watkins, et al. -
Spectral sensitivity of guppy visual pigments reconstituted in vitro to resolve association of opsins with cone cell types
Abstract The guppy (Poecilia reticulata) shows remarkable variation of photoreceptor cells in the retina, especially those sensitive to middle-to-long wavelengths of light. Microspectrophotometry (MSP) has revealed varying “green”, “green-yellow”...
2016 / Shoji Kawamura, Satoshi Kasagi, Daisuke Kasai, Ayumi Tezuka, Ayako Shoji, et al. -
Constitutive transgene expression of Stem Cell Antigen-1 in the hair follicle alters the sensitivity to tumor formation and progression
Abstract The cell surface protein Stem Cell Antigen-1 (Sca-1) marks stem or progenitor cells in several murine tissues and is normally upregulated during cancer development. Although the specific function of Sca-1 remains unknown, Sca-1 seems to...
2017 / Rikke Christensen, David M. Owens, Annette C. Füchtbauer, Anders Gunnarsson, Mette Ramsing, et al. -
Models of Eucalypt phenology predict bat population flux2016 / John R. Giles, Raina K. Plowright, Peggy Eby, Alison J. Peel, Hamish McCallum
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Siderophores: More than Stealing Iron2016 / Judith Behnsen, Manuela Raffatellu
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Progranulin acts as a shared chaperone and regulates multiple lysosomal enzymes
Abstract Multifunctional factor progranulin (PGRN) plays an important role in lysosomes, and its mutations and insufficiency are associated with lysosomal storage diseases, including neuronal ceroid lipofuscinosis and Gaucher disease (GD). The first ...
2017 / Jinlong Jian, Aubryanna Hettinghouse, Chuan-ju Liu -
Whole genomic analysis of G2P[4] human Rotaviruses in Mymensingh, north-central Bangladesh
Abstract Rotavirus A (RVA) is a dominant causative agent of acute gastroenteritis in children worldwide. G2P[4] is one of the most common genotypes among human rotavirus (HRV) strains, and has been persistently prevalent in South Asia including...
2016 / Satoru Aida, Samsoon Nahar, Shyamal Kumar Paul, Muhammad Akram Hossain, Muhammad Rashidul Kabir, et al. -
Gram-positive anaerobe cocci are underrepresented in the microbiome of filaggrin-deficient human skin2016 / Patrick L.J.M. Zeeuwen, Thomas H.A. Ederveen, Danique A. van der Krieken, Hanna Niehues, Jos Boekhorst, et al.
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Mapping the topographic epitope landscape on the urokinase plasminogen activator receptor (uPAR) by surface plasmon resonance and X-ray crystallography
Abstract The urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycolipid-anchored membrane protein often expressed in the microenvironment of invasive solid cancers and high levels are generally associated with poor patient...
2015 / Baoyu Zhao, Sonu Gandhi, Cai Yuan, Zhipu Luo, Rui Li, et al. -
Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1
Summary Amyotrophic lateral sclerosis (ALS) is a fatal and rapidly progressing motor neuron disease. Astrocytic factors are known to contribute to motor neuron degeneration and death in ALS. However, the role of astrocyte in promoting motor neuron...
2017 / Pratibha Tripathi, Natalia Rodriguez-Muela, Joseph R. Klim, A. Sophie de Boer, Sahil Agrawal, et al. -
CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models2017 / Peter W. Eide, Jarle Bruun, Ragnhild A. Lothe, Anita Sveen
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Complete Genome Sequence of Escherichia coli BLR(DE3), a recA -Deficient Derivative of E. coli BL21(DE3)2017 / Philippe Goffin, Philippe Dehottay
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Interaction between toxin crystals and vegetative insecticidal proteins of Bacillus thuringiensis in lepidopteran larvae2017 / Jakub Baranek, Edyta Konecka, Adam Kaznowski
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Experience-dependent upregulation of multiple plasticity factors in the hippocampus during early REM sleep
Abstract Sleep is beneficial to learning, but the underlying mechanisms remain controversial. The synaptic homeostasis hypothesis (SHY) proposes that the cognitive function of sleep is related to a generalized rescaling of synaptic weights to...
2015 / Julien Braga Calais, Elida Benquique Ojopi, Edgard Morya, Koichi Sameshima, Sidarta Ribeiro -
No selection on immunological markers in response to a highly virulent pathogen in an Arctic breeding bird2014 / Pierre Legagneux, Lisha L. Berzins, Mark Forbes, Naomi Jane Harms, Holly L. Hennin, et al.
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The common marmoset genome provides insight into primate biology and evolution2014 / Kim C Worley, Wesley C Warren, Jeffrey Rogers, Devin Locke, Donna M Muzny, et al.
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Evolution reveals a glutathione-dependent mechanism of 3-hydroxypropionic acid tolerance
Abstract Biologically produced 3-hydroxypropionic acid (3HP) is a potential source for sustainable acrylates and can also find direct use as monomer in the production of biodegradable polymers. For industrial-scale production there is a need for...
2014 / Kanchana R. Kildegaard, Björn M. Hallström, Thomas H. Blicher, Nikolaus Sonnenschein, Niels B. Jensen, et al. -
A new species of Machaeriobia Rübsaamen, 1915 (Diptera, Cecidomyiidae) from Brazil2016 / Valéria Cid Maia, Vinícius Abexander Condé Wilson, Ricardo Ferreira Monteiro
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Reduction Impairs the Antibacterial Activity but Benefits the LPS Neutralization Ability of Human Enteric Defensin 52016 / Cheng Wang, Mingqiang Shen, Naixin Zhang, Song Wang, Yang Xu, et al.
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Big conductance calcium-activated potassium channel openers control spasticity without sedation2017 / David Baker, Gareth Pryce, Cristina Visintin, Sofia Sisay, Alexander I Bondarenko, et al.