Biological sciences topic list of research papers
-
Distribution of Antibodies Specific to the 19-kDa and 33-kDa Fragments of Plasmodium vivax Merozoite Surface Protein 1 in Two Pathogenic Strains Infecting Korean Vivax Malaria Patients
Abstract Objectives Plasmodium vivax merozoite surface protein 1 (PvMSP1) is the most intensively studied malaria vaccine candidate. Although high antibody response-inducing two C-terminal fragments of PvMSP1...
2016 / Sylvatrie-Danne Dinzouna-Boutamba, Sanghyun Lee, Ui-Han Son, Su-Min Song, Hye Soo Yun, et al. -
Comparative proteomics analyses of intraspecific differences in the response of Stipa purpurea to drought
Abstract Stipa purpurea is widely distributed along a large precipitation gradient on the Tibetan Plateau. This implies that S. purpurea from different populations may have different responses to drought stress. To explore this ...
2016 / Xiong Li, Yunqiang Yang, Shihai Yang, Xudong Sun, Xin Yin, et al. -
Enzymatic autoantibody glycan hydrolysis alleviates autoimmunity against type VII collagen
Abstract Autoantibody-mediated diseases comprise a heterogeneous group of disorders in which the pathogenic potential of autoantibodies has been clearly demonstrated. In general, their treatment relies on the long-term use of systemic...
2012 / Misa Hirose, Katerina Vafia, Kathrin Kalies, Stephanie Groth, Jürgen Westermann, et al. -
A class-wide phylogenetic assessment of Dothideomycetes
Abstract We present a comprehensive phylogeny derived from 5 genes, nucSSU, nucLSU rDNA, TEF1, RPB1 and RPB2, for 356 isolates and 41 families (six newly described in this volume) in Dothideomycetes. All currently accepted orders in the class are...
2010 / C.L. Schoch, P.W. Crous, J.Z. Groenewald, E.W.A. Boehm, T.I. Burgess, et al. -
Transcriptional profiling of foam cells in response to hypercholesterolemia
Abstract Hypercholesterolemia is a main risk factor for atherosclerosis development. Arterial macrophages, or foam cells, take-up and process lipoprotein particles deposited in arteries, and store much of the cholesterol carried by these particles...
2016 / Young-Hwa Goo, Vijay K. Yechoor, Antoni Paul -
The cell biology of late blight disease
Late blight, caused by the oomycete Phytophthora infestans, is a major global disease of potato and tomato. Cell biology is teaching us much about the developmental stages associated with infection, especially the haustorium, which is a site of intimate...
2016 / Stephen C Whisson, Petra C Boevink, Shumei Wang, Paul RJ Birch -
Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis
Summary Oncogenic mutations of FLT3 and KIT receptors are associated with poor survival in patients with acute myeloid leukemia (AML) and myeloproliferative neoplasms (MPNs), and currently available drugs are largely ineffective. Although Stat5 has...
2014 / Anindya Chatterjee, Joydeep Ghosh, Baskar Ramdas, Raghuveer Singh Mali, Holly Martin, et al. -
Direct observation of spatially isothermal equiaxed solidification of an Al–Cu alloy in microgravity on board the MASER 13 sounding rocket
Abstract For the first time, isothermal equiaxed solidification of a metallic alloy has been observed in situ in space, providing unique benchmark experimental data. The experiment was completed on board the MASER 13 sounding rocket, launched in...
2016 / A.G. Murphy, R.H. Mathiesen, Y. Houltz, J. Li, C. Lockowandt, et al. -
Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B
Abstract Frontotemporal dementia (FTD) is an early onset neurodegenerative disease. Mutations in several genes cause familial FTD and one of them is charged multivesicular body protein 2B (CHMP2B) on chromosome 3 (FTD3), a component of the endosomal ...
2016 / Yu Zhang, Benjamin Schmid, Troels T. Nielsen, Jørgen E. Nielsen, Christian Clausen, et al. -
Immunohistochemical evidence of tissue hypoxia and astrogliosis in the rostral ventrolateral medulla of spontaneously hypertensive rats
Abstract Increased activity of the sympathetic nervous system has been highlighted as a key factor that contributes to the development and maintenance of arterial hypertension. However, the factors that precipitate sustained increases in sympathetic ...
2016 / Tymoteusz Turlejski, Ibrahim Humoud, Roshni Desai, Kenneth J. Smith, Nephtali Marina -
Transcriptome sequencing of maraena whitefish (Coregonus maraena)
Abstract Maraena whitefish (Coregonus maraena, Bloch, 1779) is a high-quality food fish belonging to the family Salmonidae with considerable economic relevance in the Baltic area. Aquaculture of this species is fundamental for its successful...
2016 / Andreas Brietzke, Andreas Borchel, Simone Altmann, Mareen Nipkow, Alexander Rebl, et al. -
From science to action: Principles for undertaking environmental research that enables knowledge exchange and evidence-based decision-making
Abstract Effective conservation requires knowledge exchange among scientists and decision-makers to enable learning and support evidence-based decision-making. Efforts to improve knowledge exchange have been hindered by a paucity of...
2016 / C. Cvitanovic, J. McDonald, A.J. Hobday -
Overexpression of SRC-3 promotes esophageal squamous cell carcinoma aggressiveness by enhancing cell growth and invasiveness2016 / Fang-Ping Xu, Yan-Hui Liu, Xin-Lan Luo, Fen Zhang, Hai-Yu Zhou, et al.
-
HPLC-MS profiling of the multidrug-resistance modifying resin glycoside content of Ipomoea alba seeds2017 / Jhon Castañeda-Gómez, Daniel Rosas-Ramírez, Sara Cruz-Morales, Mabel Fragoso-Serrano, Rogelio Pereda-Miranda
-
Surface architecture of Histoplasma capsulatum2011 / Allan J. Guimarães, Joshua D. Nosanchuk
-
Stress activates the nucleus incertus and modulates plasticity in the hippocampo-medial prefrontal cortical pathway
Abstract The nucleus incertus (NI) is a small cluster of brainstem neurons presumed to play a role in stress responses. We show that swim stress (normal water: 30min and cold water: 20min) and elevation stress robustly induced c-Fos expression in...
2015 / Ramamoorthy Rajkumar, You Wu, Usman Farooq, Wei Hao Tan, Gavin S. Dawe -
Multi-omics “upstream analysis” of regulatory genomic regions helps identifying targets against methotrexate resistance of colon cancer
Abstract We present an “upstream analysis” strategy for causal analysis of multiple “-omics” data. It analyzes promoters using the TRANSFAC database, combines it with an analysis of the upstream signal transduction pathways and identifies master...
2016 / Alexander E. Kel, Philip Stegmaier, Tagir Valeev, Jeannette Koschmann, Vladimir Poroikov, et al. -
Improved transgene expression in doxycycline-inducible embryonic stem cells by repeated chemical selection or cell sorting
Abstract Transgene-mediated programming is a preeminent strategy to direct cellular identity. To facilitate cell fate switching, lineage regulating genes must be efficiently and uniformly induced. However, gene expression is often heterogeneous in...
2016 / Renáta Bencsik, Pal Boto, Renáta Nóra Szabó, Bianka Monika Toth, Emilia Simo, et al. -
The crucial role of vitamin C and its transporter (SVCT2) in bone marrow stromal cell autophagy and apoptosis
Abstract Vitamin C is an antioxidant that plays a vital role in various biological processes including bone formation. Previously, we reported that vitamin C is transported into bone marrow stromal cells (BMSCs) through the sodium dependent Vitamin...
2015 / Rajnikumar Sangani, Sudharsan Periyasamy-Thandavan, Rajneesh Pathania, Saif Ahmad, Ammar Kutiyanawalla, et al. -
Methods for comparing multiple digital PCR experiments
Abstract The estimated mean copy per partition (λ) is the essential information from a digital PCR (dPCR) experiment because λ can be used to calculate the target concentration in a sample. However, little information is available how to...
2016 / Michał Burdukiewicz, Stefan Rödiger, Piotr Sobczyk, Mario Menschikowski, Peter Schierack, et al.