Biological sciences topic list of research papers
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Neurons Differentiated from Transplanted Stem Cells Respond Functionally to Acoustic Stimuli in the Awake Monkey Brain
Summary Here, we examine whether neurons differentiated from transplanted stem cells can integrate into the host neural network and function in awake animals, a goal of transplanted stem cell therapy in the brain. We have developed a technique in...
2016 / Jing-kuan Wei, Wen-chao Wang, Rong-wei Zhai, Yu-hua Zhang, Shang-chuan Yang, et al. -
In Vivo Interleukin-13-Primed Macrophages Contribute to Reduced Alloantigen-Specific T Cell Activation and Prolong Immunological Survival of Allogeneic Mesenchymal Stem Cell Implants2016 / Chloé J. Hoornaert, Evi Luyckx, Kristien Reekmans, Maxime Dhainaut, Caroline Guglielmetti, et al.
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Multi-PK antibodies: Powerful analytical tools to explore the protein kinase world
Abstract Diverse biological events are regulated through protein phosphorylation mediated by protein kinases. Some of these protein kinases are known to be involved in the pathogenesis of various diseases. Although 518 protein kinase genes were...
2017 / Yasunori Sugiyama, Isamu Kameshita -
Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: ‘reverse’ antagonistic pleiotropy?2016 / Nathan Basisty, Dao-Fu Dai, Arni Gagnidze, Lemuel Gitari, Jeanne Fredrickson, et al.
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Characterization of Pajaroellobacter abortibovis, the etiologic agent of epizootic bovine abortion
Abstract Epizootic bovine abortion (EBA), first identified in the 1950s, is a major contributor of economic loss to western U.S. beef producers. The causative agent proved elusive for over fifty years until a novel Deltaproteobacteria was identified ...
2016 / Roxann S. Brooks, Myra T. Blanchard, Kristin A. Clothier, Scott Fish, Mark L. Anderson, et al. -
RRM1*151A>T,RRM1-756T>C, andRRM1-585T>Gis associated with increased susceptibility of lung cancer in Chinese patients2016 / Xiao-Ling Xu, Ji Zheng, Wei-Min Mao, Zhi-Qiang Ling
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Metabolite transport and associated sugar signalling systems underpinning source/sink interactions
Abstract Metabolite transport between organelles, cells and source and sink tissues not only enables pathway co-ordination but it also facilitates whole plant communication, particularly in the transmission of information concerning resource...
2016 / Cara A. Griffiths, Matthew J. Paul, Christine H. Foyer -
The Luteinizing Hormone-Testosterone Pathway Regulates Mouse Spermatogonial Stem Cell Self-Renewal by Suppressing WNT5A Expression in Sertoli Cells
Summary Spermatogenesis originates from self-renewal of spermatogonial stem cells (SSCs). Previous studies have reported conflicting roles of gonadotropic pituitary hormones in SSC self-renewal. Here, we explored the role of hormonal regulation of...
2016 / Takashi Tanaka, Mito Kanatsu-Shinohara, Zhenmin Lei, C.V. Rao, Takashi Shinohara -
Empirically based models of oceanographic and biological influences on Pacific Herring recruitment in Prince William Sound
Abstract Abundances of small pelagic fish can change dramatically over time and are difficult to forecast, partially due to variable numbers of fish that annually mature and recruit to the spawning population. Recruitment strength of age-3 Pacific...
2017 / Fletcher Sewall, Brenda Norcross, Franz Mueter, Ron Heintz -
Aspergillus nodules in chronic granulomatous disease attributable to Aspergillus ochraceus
Abstract Aspergillus ochraceus is a rare pulmonary pathogen. A 39 year old male with COPD and chronic granulomatous disease presented with severe breathlessness and recurrent infections. CT scan demonstrated multiple pulmonary...
2017 / Samihah Moazam, David W. Denning -
A Distinct Lung-Interstitium-Resident Memory CD8+ T Cell Subset Confers Enhanced Protection to Lower Respiratory Tract Infection
Summary The nature and anatomic location of the protective memory CD8+ T cell subset induced by intranasal vaccination remain poorly understood. We developed a vaccination model to assess the anatomic location of protective memory CD8+ T cells and...
2016 / Pavlo Gilchuk, Timothy M. Hill, Clifford Guy, Sean R. McMaster, Kelli L. Boyd, et al. -
OsASR5enhances drought tolerance through a stomatal closure pathway associated with ABA and H2O2signaling in rice2016 / Jinjie Li, Yang Li, Zhigang Yin, Jihong Jiang, Minghui Zhang, et al.
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Unique Requirement for ESCRT Factors in Flavivirus Particle Formation on the Endoplasmic Reticulum
Summary Flavivirus infection induces endoplasmic reticulum (ER) membrane rearrangements to generate a compartment for replication of the viral genome and assembly of viral particles. Using quantitative mass spectrometry, we identified several ESCRT...
2016 / Keisuke Tabata, Masaru Arimoto, Masashi Arakawa, Atsuki Nara, Kazunobu Saito, et al. -
TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors
Summary Deregulated cathepsin proteolysis occurs across numerous cancers, but in vivo substrates mediating tumorigenesis remain ill-defined. Applying 8-plex iTRAQ terminal amine isotopic labeling of substrates (TAILS), a systems-level N-terminome...
2016 / Anna Prudova, Vasilena Gocheva, Ulrich auf dem Keller, Ulrich Eckhard, Oakley C. Olson, et al. -
Epidemiological trends of dengue in mainland China, 2005–2015
Summary Objective To explore the epidemiological trend of dengue in mainland China. Methods Data on dengue cases reported from 2005 to 2015 were collected, and...
2017 / Jimin Sun, Liang Lu, Haixia Wu, Jun Yang, Lei Xu, et al. -
DTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds2016 / Diana M. Hendrickx, Terezinha Souza, Danyel G. J. Jennen, Jos C. S. Kleinjans
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Endocrine effects of lifelong exposure to low-dose depleted uranium on testicular functions in adult rat
Abstract Environmental toxicant exposure can induce disorders in sex steroidogenesis during fetal gonad development. Our previous study demonstrated that chronic adult exposure to a supra environmental concentration of depleted uranium (DU) does not ...
2016 / Audrey Legendre, Christelle Elie, Camille Ramambason, Line Manens, Maamar Souidi, et al. -
Cellular oxidative damage is more sensitive to biosynthetic rate than to metabolic rate: A test of the theoretical model on hornworms (Manduca sexta larvae)
Abstract We develop a theoretical model from an energetic viewpoint for unraveling the entangled effects of metabolic and biosynthetic rates on oxidative cellular damage accumulation during animal's growth, and test the model by experiments in...
2016 / Kaushalya Amunugama, Lihong Jiao, Gayla R. Olbricht, Chance Walker, Yue-Wern Huang, et al. -
The complement factor 5a receptor 1 has a pathogenic role in chronic inflammation and renal fibrosis in a murine model of chronic pyelonephritis2016 / Naheed Choudhry, Ke Li, Ting Zhang, Kun-Yi Wu, Yun Song, et al.
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Construction of a disulfide-stabilized diabody against fibroblast growth factor-2 and the inhibition activity in targeting breast cancer2016 / Yaxiong Cai, Jinxia Zhang, Xuejun Lao, Haowu Jiang, Yunfei Yu, et al.