Biological sciences topic list of research papers
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Persistent Replicative Stress Alters Polycomb Phenotypes and Tissue Homeostasis in Drosophila melanogaster
Summary Polycomb group (PcG) proteins establish and maintain genetic programs that regulate cell-fate decisions. Drosophila multi sex combs (mxc) was categorized as a PcG gene based on a classical Polycomb phenotype and genetic interactions;...
2014 / Severine Landais, Cecilia D’Alterio, D. Leanne Jones -
Signaling Network Assessment of Mutations and Copy Number Variations Predict Breast Cancer Subtype-Specific Drug Targets
Summary Individual cancer cells carry a bewildering number of distinct genomic alterations (e.g., copy number variations and mutations), making it a challenge to uncover genomic-driven mechanisms governing tumorigenesis. Here, we performed exome...
2013 / Naif Zaman, Lei Li, Maria Luz Jaramillo, Zhanpeng Sun, Chabane Tibiche, et al. -
Autocrine Effects of Tumor-Derived Complement
Summary We describe a role for the complement system in enhancing cancer growth. Cancer cells secrete complement proteins that stimulate tumor growth upon activation. Complement promotes tumor growth via a direct autocrine effect that is partially...
2014 / Min Soon Cho, Hernan G. Vasquez, Rajesha Rupaimoole, Sunila Pradeep, Sherry Wu, et al. -
Ujuzi (Practical Pearl/Perle Pratique): An improvised oesophageal detector device2014 / Patrick D’Andrea, Hendrik J. Lategan, Sa’ad Lahri
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High Runx1 Levels Promote a Reversible, More-Differentiated Cell State in Hair-Follicle Stem Cells during Quiescence
Summary Quiescent hair follicle (HF) bulge stem cells (SCs) differentiate to early progenitor (EP) hair germ (HG) cells, which divide to produce transit-amplifying matrix cells. EPs can revert to SCs upon injury, but whether this dedifferentiation...
2014 / Song Eun Lee, Aiko Sada, Meng Zhang, David J. McDermitt, Shu Yang Lu, et al. -
MicroRNAs as Novel Regulators of Neuroinflammation2013 / Dominika Justyna Ksiazek-Winiarek, Magdalena Justyna Kacperska, Andrzej Glabinski
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Mouse SCNT ESCs Have Lower Somatic Mutation Load Than Syngeneic iPSCs
Summary Ectopic expression of reprogramming factors has been widely adopted to reprogram somatic nucleus into a pluripotent state (induced pluripotent stem cells [iPSCs]). However, genetic aberrations such as somatic gene mutation in the resulting...
2014 / Zhe Li, Hongxia Lu, Weifeng Yang, Jun Yong, Zhen-ning Zhang, et al. -
Th17 Cell Enhances CD8 T-Cell Cytotoxicity via IL-21 Production in Emphysema Mice2012 / Min-Chao Duan, Ying Huang, Xiao-Ning Zhong, Hai-Juan Tang
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A mixed-methods approach to understanding water use and water infrastructure in a schistosomiasis-endemic community: case study of Asamama, Ghana2016 / Karen Claire Kosinski, Alexandra V. Kulinkina, Akua Frimpomaa Atakora Abrah, Michael N. Adjei, Kara Marie Breen, et al.
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De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways
Abstract Matrix-bound constituents, such as the small leucine-rich proteoglycan biglycan, can act as powerful signaling molecules when released by limited proteolysis of the extracellular matrix or de novo synthesized by macrophages in the...
2013 / Jinyang Zeng-Brouwers, Janet Beckmann, Madalina-Viviana Nastase, Renato V. Iozzo, Liliana Schaefer -
Study of the relationship between human MIF level, MIF-794CATT5-8 microsatellite polymorphism, and susceptibility of tuberculosis in Southwest China
Abstract Objective To study the human migration inhibitory factor (MIF) level in tuberculosis (TB) patients, and the relationship between MIF-794CATT microsatellite polymorphism and susceptibility of TB in Southwest China. ...
2012 / Yanlin Li, Zhaofang Zeng, Shaoli Deng -
Differential spontaneous folding of mycolic acids from Mycobacterium tuberculosis
Abstract Mycolic acids are structural components of the mycobacterial cell wall that have been implicated in the pathogenicity and drug resistance of certain mycobacterial species. They also offer potential in areas such as rapid serodiagnosis of...
2013 / Wilma Groenewald, Mark S. Baird, Jan A. Verschoor, David E. Minnikin, Anna K. Croft -
Therapeutic Effect of C-Phycocyanin Extracted from Blue Green Algae in a Rat Model of Acute Lung Injury Induced by Lipopolysaccharide2013 / Pak-on Leung, Hao-Hsien Lee, Yu-Chien Kung, Ming-Fan Tsai, Tz-Chong Chou
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Exploration of microRNAs in porcine milk exosomes2014 / Ting Chen, Qian-Yun Xi, Rui-Song Ye, Xiao Cheng, Qi-En Qi, et al.
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Bacterial programming of host responses: coordination between type I interferon and cell death2014 / Miqdad O. Dhariwala, Deborah M. Anderson
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Target of Rapamycin Complex 2 regulates cell growth via Myc in Drosophila2015 / Ying Kuo, Huanwei Huang, Tao Cai, Tao Wang
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Cadmium alters the formation of benzo[a]pyrene DNA adducts in the RPTEC/TERT1 human renal proximal tubule epithelial cell line
Abstract Previously, we demonstrated the sensitivity of RPTEC/TERT1 cells, an immortalized human renal proximal tubule epithelial cell line, to two common environmental carcinogens, cadmium (Cd) and benzo[a]pyrene (B[a]P). Here, we measured BPDE-DNA ...
2014 / Bridget R. Simon, Mark J. Wilson, Diane A. Blake, Haini Yu, Jeffrey K. Wickliffe -
Molecular Tooth Decay2009 / Rob DeSalle
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Transcriptome sequencing, annotation and polymorphism detection in the hop bush, Dodonaea viscosa2015 / Matthew J. Christmas, Ed Biffin, Andrew J. Lowe
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Levetiracetam Differentially Alters CD95 Expression of Neuronal Cells and the Mitochondrial Membrane Potential of Immune and Neuronal Cells in vitro2014 / Susannah K. Rogers, Lee A. Shapiro, Richard P. Tobin, Benjamin Tow, Aleksej Zuzek, et al.