Biological sciences topic list of research papers
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The origin of cancer stem cells2014 / Hien T. Dang, Anuradha Budhu, Xin W. Wang
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Mosquitocidal properties of Solanum trilobatum L. (Solanaceae) leaf extracts against three important human vector mosquitoes (Diptera: Culicidae)
Abstract Objective To determine the larvicidal and pupicidal activites of Solanum trilobatum (S. trilobatum) leaf extracts against Aedes aegypti (Ae. aegypti), Culex quinquefasciatus (Cx. quinquefasciatus) and Anopheles stephensi...
2013 / Selvaraj Premalatha, Kuppusamy Elumalai, Alagarmalai Jeyasankar -
Ligand-independent androgen receptors promote ovarian teratocarcinoma cell growth by stimulating self-renewal of cancer stem/progenitor cells
Abstract Background Ovarian teratocarcinoma (OVTC) arises from germ cells and contains a high percentage of cancer stem/progenitor cells (CSPCs), which promote cancer development through their ability to self-renew. Androgen and...
2014 / Wei-Min Chung, Wei-Chun Chang, Lumin Chen, Tze-Yi Lin, Liang-Chi Chen, et al. -
Study on the pathogenesis of autoimmune-type recurrent spontaneous abortion by establishing a new mouse model
Abstract Objective To establish a new mouse model for autoimmune-type recurrent spontaneous abortion (AI-RSA) and demonstrate the potential role of intrauterine immunization with β2GP-1-like antigen in AI-RSA, we performed an...
2014 / Shijin Xiao, Xuefeng Lu, Xiaoqiong Li, Li Zhang, Shimin Bao, et al. -
Integrated mRNA and microRNA transcriptome sequencing characterizes sequence variants and mRNA–microRNA regulatory network in nasopharyngeal carcinoma model systems
Abstract Nasopharyngeal carcinoma (NPC) is a prevalent malignancy in Southeast Asia among the Chinese population. Aberrant regulation of transcripts has been implicated in many types of cancers including NPC. Herein, we characterized mRNA and miRNA...
2014 / Carol Ying-Ying Szeto, Chi Ho Lin, Siu Chung Choi, Timothy T.C. Yip, Roger Kai-Cheong Ngan, et al. -
A glucagon analog chemically stabilized for immediate treatment of life-threatening hypoglycemia
Abstract For more than half a century glucagon has been used as a critical care medicine in the treatment of life-threatening hypoglycemia. It is commercially supplied as a lyophilized powder intended to be solubilized in dilute aqueous hydrochloric ...
2014 / Joseph Chabenne, Maria DiMarchi Chabenne, Yan Zhao, Jay Levy, David Smiley, et al. -
Role of extracellular ATP and P2 receptor signaling in regulating renal cyst growth and interstitial inflammation in polycystic kidney disease2013 / Gopi Rangan
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Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: Further characterization of presynaptic mechanisms
Abstract Pregabalin is widely used as an analgesic for the treatment of neuropathic pain. In the present experiments using mouse spinal slices, we recorded electrically evoked glutamatergic excitatory postsynaptic currents (eEPSCs) from superficial...
2013 / Rie Matsuzawa, Tomonori Fujiwara, Kohei Nemoto, Teruyuki Fukushima, Shigeki Yamaguchi, et al. -
A mathematical model of the sterol regulatory element binding protein 2 cholesterol biosynthesis pathway
Abstract Cholesterol is one of the key constituents for maintaining the cellular membrane and thus the integrity of the cell itself. In contrast high levels of cholesterol in the blood are known to be a major risk factor in the development of...
2014 / Bonhi S. Bhattacharya, Peter K. Sweby, Anne-Marie Minihane, Kim G. Jackson, Marcus J. Tindall -
Noncanonical Reactions of Flavoenzymes2012 / Pablo Sobrado
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Analysis of Stylometric Variables in Long and Short Texts
Abstract This paper presents some experiments in the task of authorship attribution. We achieve this task by a stylometric analysis of some stylistic markers tested in two Spanish corpora. The first corpus is composed of long texts written by...
2013 / Fernanda López-Escobedo, Carlos-Francisco Méndez-Cruz, Gerardo Sierra, Julián Solórzano-Soto -
Polimorfismos genéticos e endometriose: A contribuição dos genes que regulam a função vascular e o remodelamento de tecidos
Resumo A endometriose é uma doença ginecológica benigna caracterizada pela presença e crescimento de células endometriais fora do útero. Fatores genéticos, endócrinos, imunológicos e ambientais têm sido sugeridos em sua patogênese. Um grande número...
2012 / Alessandra Bernadete Trovó de Marqui -
Structural Determinants of Unique Properties of Human IgG4-Fc
Abstract Human IgG4, normally the least abundant of the four subclasses of IgG in serum, displays a number of unique biological properties. It can undergo heavy-chain exchange, also known as Fab-arm exchange, leading to the formation of monovalent...
2013 / Anna M. Davies, Theo Rispens, Pleuni Ooijevaar-de Heer, Hannah J. Gould, Roy Jefferis, et al. -
The mitochondrial permeability transition pore is a dispensable element for mitochondrial calcium efflux
Abstract The mitochondrial permeability transition pore (mPTP) has long been known to have a role in mitochondrial calcium (Ca2+) homeostasis under pathological conditions as a mediator of the mitochondrial permeability transition and the activation ...
2014 / Elena De Marchi, Massimo Bonora, Carlotta Giorgi, Paolo Pinton -
Mutant spectrum of dengue type 1 virus in the plasma of patients from the 2006 epidemic in South China
Summary The aim of the present study was to explore the mutant spectrum of dengue type 1 virus (DENV-1) within individuals during the 2006 dengue epidemic in South China. A 513-bp fragment including most of domain III of the envelope (E) gene was...
2013 / Zeng Tu, Yong-lin He, He Lu, Lei Xu, Zhi-bang Yang, et al. -
Car windshield fragments as cheap alternative glass beads for homogenization of Mycobacterium tuberculosis cultures in a resource-limited setting
Abstract Tuberculosis is a global health problem which has been compounded by the emergence and rapid spread of drug resistant strains. Phenotypic drug susceptibility testing of Mycobacterium tuberculosis usually requires homogenization of cultures...
2014 / Ernest Afu Ochang, Dami Collier, Ibidunni Bode-Sojobi, Rita Oladele, Oyinlola O. Oduyebo -
The bile acid TGR5 membrane receptor: From basic research to clinical application
Abstract The TGR5 receptor (or GP-BAR1, or M-BAR) was characterized ten years ago as the first identified G-coupled protein receptor specific for bile acids. TGR5 gene expression is widely distributed, including endocrine glands, adipocytes,...
2014 / Henri Duboc, Yvette Taché, Alan F. Hofmann -
A pSMAD/CDX2 Complex Is Essential for the Intestinalization of Epithelial Metaplasia
Summary The molecular mechanisms leading to epithelial metaplasias are poorly understood. Barrett's esophagus is a premalignant metaplastic change of the esophageal epithelium into columnar epithelium, occurring in patients suffering from...
2014 / Luigi Mari, Francesca Milano, Kaushal Parikh, Danielle Straub, Vincent Everts, et al. -
Prediction of the maximum acceptable weight of lift from the frequency of lift
Abstract It is known that maximum acceptable weight of lift (MAWL) decreases as the frequency of lifting increases. The purpose of this study was to quantify the relationship between lifting frequency and the MAWL, and to generate models for...
2012 / A.D.J. Pinder, M.G. Boocock -
Anticancer, antiobesity, and anti-inflammatory activity of Artemisia species in vitro
Abstract Objective To investigate the anticancer, anti-inflammatory, and antiobesity activity of methanol extracts of eight distinct species: Artemisia Stolonifera (AST), Artemisia Selengensis (ASE), Artemisia Japonica, Artemisia...
2013 / Eunjeong Choi, Heesook Park, Jehyuk Lee, Gunhee Kim