Basic medicine topic list of research papers
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Reduced Penetrance and Variable Expression of SCN5A Mutations and the Importance of Co-inherited Genetic Variants: Case Report and Review of the Literature
Abstract Mutations in the SCN5A gene are responsible for multiple phenotypical presentations including Brugada syndrome, long QT syndrome, progressive familial heart block, sick sinus syndrome, dilated cardiomyopathy, lone atrial fibrillation and...
2016 / T. Robyns, D. Nuyens, L. Van Casteren, A. Corveleyn, T. De Ravel, et al. -
Cross talk of the first-line defense TLRs with PI3K/Akt pathway, in preconditioning therapeutic approach2015 / Fatemeh Pourrajab, Mohammad Baghi Yazdi, Mojtaba Babaei Zarch, Mohammadali Babaei Zarch, Seyedhossein Hekmatimoghaddam
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Platelet activation independent of pulmonary inflammation contributes to diesel exhaust particulate-induced promotion of arterial thrombosis2016 / Caroline M. Tabor, Catherine A. Shaw, Sarah Robertson, Mark R. Miller, Rodger Duffin, et al.
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Carotid body chemoreceptors, sympathetic neural activation, and cardiometabolic disease2016 / Rodrigo Iturriaga, Rodrigo Del Rio, Juan Idiaquez, Virend K. Somers
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Editorial: Silent myocardial ischemia due to coronary artery spasm2015 / Masami Kosuge, Kazuo Kimura
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Inhibitory effects of ginsenosides on basic fibroblast growth factor-induced melanocyte proliferation
Abstract Background UV-B-exposed keratinocytes secrete various paracrine factors. Among these factors, basic fibroblast growth factor (bFGF) stimulates the proliferation of melanocytes. Ginsenosides, the major active compounds of...
2016 / Jieun Lee, Jong Il Park, Cheol Hwan Myung, Jae Sung Hwang -
Severe hypoxemia follows hypoxic pulmonary vasoconstriction and/or hypoxic pulmonary vasoconstriction inhibition by inhaled anesthetics: prognostic potential of 100% shunt fractions2016 / Menekse Oksar, Onur Koyuncu, Selim Turhanoglu
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Genetically Modified Mouse Models Used for Studying the Role of the AT2 Receptor in Cardiac Hypertrophy and Heart Failure2011 / Maria D. Avila, James P. Morgan, Xinhua Yan
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Chemotherapeutic Efficacy of Phosphodiesterase Inhibitors in Chagasic Cardiomyopathy
Summary Molecular mechanisms of Trypanosoma cruzi (Tc)-induced Chagasic cardiomyopathy (CCM) are not well understood. The NO-cGMP-PKG1α pathway maintains cardiac homeostasis and inotropy and may be disturbed due to phosphodiesterase (PDE5)-mediated...
2016 / Jian-jun Wen, Xianxiu Wan, John Thacker, Nisha Jain Garg -
Microbiota Alterations in Inflammatory Bowel Diseases: From Correlation to Causality2016 / Benoit Chassaing
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Microtubule-Mediated Misregulation of Junctophilin-2 Underlies T-Tubule Disruptions and Calcium Mishandling in mdx Mice
Summary Cardiac myocytes from the mdx mouse, the mouse model of Duchenne muscular dystrophy, exhibit t-tubule disarray and increased calcium sparks, but a unifying molecular mechanism has not been elucidated. Recently, improper trafficking of...
2016 / Kurt W. Prins, Michelle L. Asp, Huiliang Zhang, Wang Wang, Joseph M. Metzger -
Effects and mechanism of moderate aerobic exercise on impaired fasting glucose improvement2015 / Huo-cheng Liao, Si-gan Zhong, Peng Li, Wei-bin Chen, Cheng Cheng, et al.
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Sleep in space as a new medical frontier: the challenge of preserving normal sleep in the abnormal environment of space missions
Abstract Space agencies such as the National Aeronautics and Space Administration of the United States, the Russian Federal Space Agency, the European Space Agency, the China National Space Administration, the Japan Aerospace Exploration Agency, and ...
2016 / Seithikurippu R. Pandi-Perumal, Alain A. Gonfalone -
The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy
Summary Heterozygous mice (αMHC 403/+ ) expressing the human disease-causing mutation Arg403Gln exhibit cardinal features of hypertrophic cardiomyopathy (HCM) including hypertrophy,...
2016 / Helena M. Viola, Victoria P.A. Johnstone, Henrietta Cserne Szappanos, Tara R. Richman, Tatiana Tsoutsman, et al. -
No reflow phenomenon in percutaneous coronary interventions in ST-segment elevation myocardial infarction
Abstract Percutaneous coronary intervention (PCI) is effective in opening the infarct related artery and restoring thrombolysis in myocardial infarction flow 3 (TIMI-flow 3) in large majority of ST-elevation myocardial infarction (STEMI). However...
2016 / Sanjiv Gupta, Madan Mohan Gupta -
Influences of rapid pacing-induced electrical remodeling on pharmacological manipulation of the atrial refractoriness in rabbits
Abstract Electrical remodeling plays a pivotal role in maintaining the reentry during atrial fibrillation. In this study, we assessed influence of electrical remodeling on pharmacological manipulation of the atrial refractoriness in rabbits. We used ...
2016 / Toshiki Chiba, Naoto Kondo, Akira Takahara -
Cardiac fibrosis in myocardial infarction—from repair and remodeling to regeneration2016 / Virpi Talman, Heikki Ruskoaho
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Correcting thrombin generation ex vivo using different haemostatic agents following cardiac surgery requiring the use of cardiopulmonary bypass2014 / Charles L. Percy, Rudolf Hartmann, Rhidian M. Jones, Subramaniam Balachandran, Dheeraj Mehta, et al.
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Sex-specific effects of LiCl treatment on preservation of renal function and extended life-span in murine models of SLE: perspective on insights into the potential basis for survivorship in NZB/W female mice2016 / David A. Hart
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Exogenous Administration of Recombinant MIF at Physiological Concentrations Failed to Attenuate Infarct Size in a Langendorff Perfused Isolated Mouse Heart Model2016 / Xavier Rossello, Niall Burke, Christian Stoppe, Jurgen Bernhagen, Sean M. Davidson, et al.