Basic medicine topic list of research papers
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Improvement of Myocardial Function Following Catheter-Based Renal Denervation in Heart Failure
Summary Renal denervation (RD) is a potential novel nonpharmacological therapy for heart failure (HF). We performed bilateral catheter-based RD in 10 adult pigs and compared them with 10 control subjects after induction of HF to investigate the...
2017 / Song-Yan Liao, Zhe Zhen, Yuan Liu, Kai-Wing Au, Wing-Hon Lai, et al. -
Association between plasma ADAMTS-7 levels and severity of disease in patients with stable obstructive coronary artery disease2016 / Jie Yu, Boda Zhou, Haiyi Yu, Jiangli Han, Ming Cui, et al.
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Microvascular pathological features and changes in related injury factors in a rat acute blood stasis model
Abstract OBJECTIVE To examine the microvascular pathological characteristics and changes in related injury factors in a rat model of acute blood stasis. METHODS A...
2017 / Zhang Junxiu, Feng Yu, Li Shaodan, Liu Yi, Zhang Yin, et al. -
Diagnostic and therapeutic aspects of β1-adrenergic receptor autoantibodies in human heart disease
Abstract Growing evidence indicates a cardio-pathogenic role of autoantibodies against β1-adrenergic receptors (β1AR). In particular autoantibodies stimulating β1AR-mediated cAMP-production (i.e. agonistic β1AR autoantibodies) play a paramount role...
2014 / Beatrice Bornholz, Dirk Roggenbuck, Roland Jahns, Fritz Boege -
Paving the way for a gold standard of care for infertility treatment: improving outcomes through standardization of laboratory procedures
Abstract Infertility affects over 70 million couples globally. Access to, and interest in, assisted reproductive technologies is growing worldwide, with more couples seeking medical intervention to conceive, in particular by IVF. Despite numerous...
2017 / William Schoolcraft, Marcos Meseguer -
A Long-Term and Slow-Releasing Hydrogen Sulfide Donor Protects against Myocardial Ischemia/Reperfusion Injury2017 / Xiaotian Sun, Wenshuo Wang, Jing Dai, Sheng Jin, Jiechun Huang, et al.
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Role of cardiovascular magnetic resonance in acute coronary syndrome2015 / Jan Bogaert, Ingo Eitel
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Acute CD47 Blockade During Ischemic Myocardial Reperfusion Enhances Phagocytosis-Associated Cardiac Repair
Summary Our data suggest that, after a myocardial infarction, integrin-associated protein CD47 on cardiac myocytes is elevated. In culture, increased CD47 on the surface of dying cardiomyocytes impairs phagocytic removal by immune cell macrophages....
2017 / Shuang Zhang, Xin-Yi Yeap, Matthew DeBerge, Nivedita K. Naresh, Kevin Wang, et al. -
Cardiovascular risk of adipokines: a review2017 / Frédéric Dutheil, Brett Ashley Gordon, Geraldine Naughton, Edward Crendal, Daniel Courteix, et al.
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The effects of aerobic and anaerobic exercises on circulating soluble-Klotho and IGF-I in young and elderly adults and in CAD patients2017 / Moran S Saghiv, D Ben Sira, E Goldhammer, M Sagiv
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Cisplatin selects short forms of the mitochondrial DNA OriB variant (16184–16193 poly-cytosine tract), which confer resistance to cisplatin2017 / Taku Amo, Naomi Kamimura, Hiromasa Asano, Sadamitsu Asoh, Shigeo Ohta
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Folic acid reduces doxorubicin-induced cardiomyopathy by modulating endothelial nitric oxide synthase2017 / Yanti Octavia, Georgios Kararigas, Martine de Boer, Ihsan Chrifi, Rinrada Kietadisorn, et al.
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Role of oxidative stress in cardiovascular disease outcomes following exposure to ambient air pollution
Abstract Exposure to ambient air pollution is associated with adverse cardiovascular outcomes. These are manifested through several, likely overlapping, pathways including at the functional level, endothelial dysfunction, atherosclerosis,...
2017 / Frank J. Kelly, Julia C. Fussell -
Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock2016 / Yuan Yu, Xiaoying Xu, Lu Liu, Sheng Mao, Tingting Feng, et al.
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Differences in immune responses between CMV-seronegative and -seropositive patients with myocardial ischemia and reperfusion2015 / Evgeniya V. Shmeleva, Stephen E. Boag, Santosh Murali, Karim Bennaceur, Rajiv Das, et al.
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Altered ghrelin secretion in mice in response to diet-induced obesity and Roux-en-Y gastric bypass
Abstract The current study examined potential mechanisms for altered circulating ghrelin levels observed in diet-induced obesity (DIO) and following weight loss resulting from Roux-en-Y gastric bypass (RYGB). We hypothesized that circulating ghrelin ...
2014 / Aki Uchida, Juliet F. Zechner, Bharath K. Mani, Won-mee Park, Vincent Aguirre, et al. -
Titration to target dose of bisoprolol vs. carvedilol in elderly patients with heart failure: the CIBIS-ELD trial2011 / Hans-Dirk Düngen, Svetlana Apostolović, Simone Inkrot, Elvis Tahirović, Agnieszka Töpper, et al.
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Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential
Abstract Acetaminophen (APAP) hepatotoxicity is characterized by an extensive oxidative stress. However, its source, pathophysiological role and possible therapeutic potential if targeted, have been controversially described. Earlier studies argued...
2016 / Kuo Du, Anup Ramachandran, Hartmut Jaeschke -
Down-regulation of fibroblast growth factor 2 and its co-receptors heparan sulfate proteoglycans by resveratrol underlies the improvement of cardiac dysfunction in experimental diabetes
Abstract Cardiac remodeling in diabetes involves cardiac hypertrophy and fibrosis, and fibroblast growth factor 2 (FGF2) is an important mediator of this process. Resveratrol, a polyphenolic antioxidant, reportedly promotes the improvement of...
2016 / Célia Maria Cássaro Strunz, Alessandra Roggerio, Paula Lázara Cruz, Ana Paula Pacanaro, Vera Maria Cury Salemi, et al. -
Neuronal Na+ Channels Are Integral Components of Pro-Arrhythmic Na+/Ca2+ Signaling Nanodomain That Promotes Cardiac Arrhythmias During β-Adrenergic Stimulation
Summary Although triggered arrhythmias including catecholaminergic polymorphic ventricular tachycardia (CPVT) are often caused by increased levels of circulating catecholamines, the mechanistic link between β-adrenergic receptor (AR) stimulation and ...
2016 / Przemysław B. Radwański, Hsiang-Ting Ho, Rengasayee Veeraraghavan, Lucia Brunello, Bin Liu, et al.