Basic medicine topic list of research papers
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The endogenous preproglucagon system is not essential for gut growth homeostasis in mice
Abstract Objective The prevalence of obesity and related co-morbidities is reaching pandemic proportions. Today, the most effective obesity treatments are glucagon-like peptide 1 (GLP-1) analogs and bariatric surgery....
2017 / Pernille Wismann, Pernille Barkholt, Thomas Secher, Niels Vrang, Henrik B. Hansen, et al. -
Short-Term Administration of Serelaxin Produces Predominantly Vascular Benefits in the Angiotensin II/L-NAME Chronic Heart Failure Model
Summary In patients hospitalized with acute heart failure, temporary serelaxin infusion reduced 6-month mortality through unknown mechanisms. This study therefore explored the cardiovascular effects of temporary serelaxin administration in mice...
2017 / Joseph C. McCarthy, Mark Aronovitz, Jennifer J. DuPont, Timothy D. Calamaras, Iris Z. Jaffe, et al. -
Impaired myocardial relaxation with exercise determines peak aerobic exercise capacity in heart failure with preserved ejection fraction2017 / Cory Trankle, Justin M. Canada, Leo Buckley, Salvatore Carbone, Dave Dixon, et al.
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Fetuin-A as a predicator of sarcopenic left ventricular dysfunction2015 / Wei-Ting Chang, Wei-Chuan Tsai, Chih-Hsing Wu, Yen-Wei Lee, Yun-Lin Tai, et al.
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Quantifying the area-at-risk of myocardial infarction in-vivo using arterial spin labeling cardiac magnetic resonance2017 / Rachel K. Dongworth, Adrienne E. Campbell-Washburn, Hector A. Cabrera-Fuentes, Heerajnarain Bulluck, Thomas Roberts, et al.
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Olmesartan reverses not only vascular endothelial dysfunction but cardiac diastolic dysfunction in hypertensive patients with heart failure with preserved ejection fraction — ORION study2015 / Eiichiro Yamamoto, Keisuke Ohba, Yoshihiro Hirata, Takanori Tokitsu, Koichiro Fujisue, et al.
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Development and outcomes of a primary care-based sleep assessment service in Canterbury, New Zealand2017 / Michael J. Epton, Paul T. Kelly, Brett I. Shand, Sallyanne V. Powell, Judith N. Jones, et al.
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Influence of renal impairment on aldosterone status, calcium metabolism, and vasopressin activity in outpatients with systolic heart failure2017 / Helle Bosselmann, Niels Tonder, György Sölétormos, Freja Gaborit, Kasper Rossing, et al.
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HMGB1, an innate alarmin, plays a critical role in chronic inflammation of adipose tissue in obesity
Abstract Obesity has emerged as an imminent global public health concern over the past several decades. It has now become evident that obesity is characterized by the persistent and low-grade inflammation in the adipose tissue, and serves as an...
2017 / Jing Zhang, Lei Zhang, Shu Zhang, Qilin Yu, Fei Xiong, et al. -
Loss of succinyl-CoA synthase ADP-forming β subunit disrupts mtDNA stability and mitochondrial dynamics in neurons2017 / Yujun Zhao, Jing Tian, Shaomei Sui, Xiaodong Yuan, Hao Chen, et al.
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IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice2017 / Yusuke Shintani, Tomoya Ito, Laura Fields, Manabu Shiraishi, Yuki Ichihara, et al.
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An observational study of the association among interatrial adiposity by computed tomography measure, insulin resistance, and left atrial electromechanical disturbances in heart failure2016 / Chung-Lieh Hung, Chun-Ho Yun, Yau-Huei Lai, Kuo-Tzu Sung, Hiram G. Bezerra, et al.
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Prognostic value of the absolute lymphocyte count in patients admitted for acute heart failure2016 / Valentina Carubelli, Ivano Bonadei, Anna I. Castrini, Elio Gorga, Alice Ravera, et al.
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A change of heart: a transforming view of cardiac function2017 / Alexander R. Pinto
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Mitochondrial Dysfunction and Altered Renal Metabolism in Dahl Salt-Sensitive Rats2017 / Zhengjun Wang, Qiong Sun, Na Sun, Mingyu Liang, Zhongmin Tian
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Electrophysiologic effects of the I K 1 inhibitor PA‐6 are modulated by extracellular potassium in isolated guinea pig hearts2017 / Gregory S. Hoeker, Mark A. Skarsfeldt, Thomas Jespersen, Steven Poelzing
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Left ventricular remodeling leads to heart failure in mice with cardiac‐specific overexpression of VEGF‐B 167 : echocardiography and magnetic resonance imaging study2017 / Line Lottonen‐Raikaslehto, Riina Rissanen, Erika Gurzeler, Mari Merentie, Jenni Huusko, et al.
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Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases
Abstract Purinergic signaling, mediated mainly by G protein-coupled P2Y receptors (P2YRs), is now attracting attention as a new therapeutic target for preventing or treating cardiovascular diseases. Observations using mice with genetically modified...
2017 / Akiyuki Nishimura, Caroline Sunggip, Sayaka Oda, Takuro Numaga-Tomita, Makoto Tsuda, et al. -
Plasma von Willebrand factor level is transiently elevated in a rat model of acute myocardial infarction2015 / YAN LI, LIQUN LI, FENGYUN DONG, LING GUO, YINGLONG HOU, et al.
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Significant elevation of biomarkers of myocardial necrosis after coronary artery bypass grafting without myocardial infarction established assessed by cardiac magnetic resonance2017 / Leandro Menezes Alves da Costa, Whady Hueb, Cesar Higa Nomura, Alexandre Ciappina Hueb, Alexandre Volney Villa, et al.