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0Journal of Cardiovascular Magnetic Resonance
POSTER PRESENTATION Open Access
Moderate intensity supine exercise causes decreased cardiac volumes and increased outer volume variations - a cardiac magnetic resonance imaging study
TO 1 * 1 In 1
Katarina Steding-Ehrenborg ', Robert Jablonowski , Per M Arvidsson , Marcus Carlsson , Hakan Arheden
From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. 16-19 January 2014
Background
The effects on left and right ventricular (LV, RV) volumes during physical exercise remains controversial. Furthermore, no previous study has investigated the effects of exercise on longitudinal contribution to stroke volume (SV) and the outer volume variation of the heart. The aim of this study was to determine if LV, RV and total heart volumes (THV) as well as cardiac pumping mechanisms change during physical exercise compared to rest using cardiac magnetic resonance imaging (CMR).
Methods
26 healthy volunteers (6 women) underwent cine CMR at rest and exercise. Exercise was performed using a custom built ergometer for one-legged exercise in the supine position during breath hold imaging. Cardiac volumes and atrio-ventricular plane displacement were determined. Heart rate (HR) was obtained from ECG.
Results
HR increased during exercise (60 ± 2 to 94 ± 2 bpm, p < 0.001). LVEDV remained unchanged (p = 0.81) and LVESV decreased with -9 ± 18% (p < 0.05) causing LVSV to increase with 8 ± 3% (p < 0.05) (Figure 1A-C).
RVEDV and RVESV decreased (-7 ± 10% and -24 ± 14% respectively, p < 0.001) and RVSV was increased with 5 ± 17% although not statistically significant (p = 0.18) (Figure 1 D-F). Longitudinal contribution to RVSV decreased during exercise (-6 ± 15%, p < 0.05) but was unchanged for LVSV (p = 0.74). THV decreased during exercise (-4 ± 1%, p < 0.01) and total heart volume variation (THVV) increased during exercise from 5.9 ± 0.5% to 9.7 ± 0.6%, p < 0.001) (Figure 2).
Conclusions
Cardiac volumes and function are significantly altered during supine physical exercise. THV becomes significantly smaller due to decreases in RVEDV whilst LVEDV remains unchanged. THVV and consequently radial pumping increases during exercise which may improve diastolic suction during the rapid filling phase.
Funding
This study was funded by the Swedish Research Council, the Swedish Heart and Lung Foundation, Region of Scania, the Medical Faculty at Lund University, Sweden, the Swedish Heart Association and Novo Nordisk Foundation, Denmark.
1Cardiac MR Group Lund, Lund University, Skane University HospitalLund, Lund, Sweden
Full list of author information is available at the end of the article
© 2014 Steding-Ehrenborg et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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Figure 1 Left and right ventricular volumes and stroke volumes at rest and exercise. Upper panelshows no changes in left ventricular end-diastolic volumes (A) and a smallbut significant decrease in end-systolic volume (B), leading to an increased stroke volume (C). Lower panel show a significant decrease in right ventricular end-diastolic volume (D) and end-systolic volume (E). Right ventricular stroke volume increased during exercise, however not statistically significant (F). Error bars denote mean and standard error of the mean (SEM).
ED ES 4ch ED
Figure 2 Mid-ventricular short axis slices in end-diastole (ED) and end-systole (ES) during rest and exercise with the corresponding 4-chamber view (4 ch) to illustrate the location of the slice. The solid line indicates delineations for totalheart volume. In the exercise images, the dashed line shows the totalheart volume delineation copied from the corresponding resting image. The right ventricular volume is decreased whereas the left ventricle remains unchanged.
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Authors' details
1Cardiac MR Group Lund, Lund University, Skane University HospitalLund, Lund, Sweden. 2Copenhagen Muscle Research Centre, Rigshospitalet, Copenhagen, Denmark. 3Danish Research Centre for Magnetic Resonance, Hvidovre Hospital, Copenhagen, Denmark.
Published: 16 January 2014
doi:10.1186/1532-429X-16-S1-P38
Cite this article as: Steding-Ehrenborg et al: Moderate intensity supine exercise causes decreased cardiac volumes and increased outer volume variations - a cardiac magnetic resonance imaging study. Journal of Cardiovascular Magnetic Resonance 2014 16(Suppl 1):P38.
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