Scholarly article on topic 'Recommended Articles'

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Academic research paper on topic "Recommended Articles"


Objectives: The objective of this study is to report the efficacy of acupuncture and moxibustion for the treatment of fetal breech presentation.

Methods: We searched papers in PubMed by using the keywords "breech and moxibustion" and "breech and acupuncture". The search range included randomized clinical trials (RCTs), controlled clinical trials (CCTs), case reports, and case series. Each original article had to have an abstract in English. Finally, 7 RCTs out of 102 papers were included in this review. Results: Of the seven RCTs, five trials held that moxibustion or acupuncture at BL67 produced a positive effect for the correction of breech presentation, one trial indicated no beneficial effect, and one trail had no conclusion owing to the unsatisfactory compliance record of the participants.

Conclusions: Acupuncture and moxibustion may be effective in correcting fetal breech presentation. In this regard, related clinical research is worth pursuing.

Keywords: breech presentation; moxibustion; acupuncture; Korean medicine; delivery

(3) Korean Journal of Acupuncture Vol. 30, No. 1, pp. 27-36, 2013

The Review on the Study of Bee Venom in the Journals of Korean Medicine

Chang-Hyun Han, Yong-Seok Lee, Oh-Min Kwon, Young-Joon Lee*

* Corresponding Author's Affiliation: Department of Oriental Medicine Graduate School, Daegu Haany University, Gyeongsan, Korea.


Objectives: The focus of this study was changes in research pertaining to bee venom over time.

Methods: We collected 365 articles on bee venom from the OASIS system by using the keywords 'bee venom, apitoxin, apitherapy, bee sting'. We determined the number and the percentage of theses according to year, study method, journal, and subject.

Results: Of the 365 bee venom papers published in the Journal of Korean Medicine from 1976, the 205 studies associated with bee-venom clinical trials outnumbered other types of studies by a ratio of 1.3 to 1; that Journal also included 138 experimental papers and 22 literature studies. In the 205 papers associated with bee venom in clinical trials, lumbar disorders were addressed in 38 papers, upper limb disorders in 35 papers, and systemic diseases in 34 papers, followed by fewer papers addressing other disorders. When the 138 experimental papers were classified according to subject, 16 papers addressed pain reduction, 14 addressed apoptosis and anticancer effects, 13 addressed anti-inflammatory effects, and 11 addressed effects in treating arthritis, followed by fewer papers addressing other effects.

Conclusions: Bee venom is a treatment method based on the unique theory of Korean traditional medicine. The efforts, as well as the academic approaches used, to investigate bee venom are expected to produce positive results through numerous research works.

Keywords: Bee venom; Korean medicine; systemic review

(4) Journal of Pharmacopuncture, Vol. 16, No.1, pp.37~42, 2013

Effect of Geumgoeshingi-Whan Pharmacopuncture on the Blood Pressure in Spontaneously Hypertensive Rats

Meesun Lee, Sangmi Lee, Hohyn Jeong, Manyong Park, Dong-woung Kim, Bong-keun Song, Jong-Deok Lee, Ho Sub Lee, Sungchul Kim*

* Corresponding Author's Affiliation: Department of Acupuncture & Moxibustion, Wonkwang Gwangju Oriental Medical Hospital, Gwanju, Korea.


Objective: The aim of this experiment was to investigate the effect and the mechanism of Geumgoeshingi-whan (GGSGW) Pharmacopuncture at the acupoint GV 4 on the blood pressure in spontaneously hypertensive rats (SHR). Methods: SHR were injected with normal saline solution (Control-SHR group) or GGSGW Pharmacopuncture (GGSGW-SHR group) at the acupoint GV 4. The systolic arterial blood pressure and renal parameters were measured for two weeks.

Results: The systolic arterial blood pressure was decreased significantly after GGSGW Pharmacopuncture at the acupoint GV 4 in SHR, followed by a significant rise in creatine clearance. The plasma levels of aldosterone were decreased significantly after GGSGW Pharmacopunctureas were the plasma levels of atrial natriuretic peptide (ANP).

Conclusion: These results suggest that the blood pressure was decreased significantly after GGSGW Pharmacopuncture at the acupoint GV 4 in SHR and that the depressor response of the blood pressure was related to decreases in the plasma levels of aldosterone and ANP.

Keywords: Geumgoeshingi-whan, Pharmacopuncture, SHR, hypertension, ANP, Renal function

(5) Journal of Pharmacopuncture, Vol. 16, No.1, pp.43~49, 2013

Modulation of Pacemaker Potentials by Pyungwi-San in Interstitial Cells of Cajal from Murine Small Intestine- Pyungwi-San and Interstitial Cells of Cajal -

Jung Nam Kim, Ho Jun Song, Bora Lim, Young Kyu Kwon, Byung Joo Kim*

* Corresponding Author's Affiliation: Division of Longevity and Biofunctional Medicine, Pusan National University School of Korean Medicine, Yangsan, Korea.


Objective: Pyungwi-san (PWS) plays a role in a number of physiologic and pharmacologic functions in many organs. Interstitial cells of Cajal (ICCs) are pacemaker cells that generate slow waves in the gastrointestinal (GI) tract. We aimed to investigate the beneficial effects of PWS in mouse small-intestinal ICCs.

Methods: Enzymatic digestion was used to dissociate ICCs from the small intestine of a mouse. The wholecell patch-clamp configuration was used to record membrane potentials from the cultured ICCs.

Results: ICCs generated pacemaker potentials in the GI tract. PWS produced membrane depolarization in the current clamp mode. Pretreatment with a Ca2+-free solution and a thapsigargin, a Ca2+-ATPase, inhibitor in the endoplasmic reticulum, eliminated the generation of pacemaker potentials. However, only when the thapsigargin was applied in a bath solution, the membrane depolarization was not produced by PWS. Furthermore, the membrane depolarizations due to PWS were inhibited not by U-73122, an active phospholipase C inhibitor, but by chelerythrine and calphostin C, protein kinase C inhibitors.

Conclusions: These results suggest that PWS might affect GI motility by modulating the pacemaker activity in the ICCs. Keywords: interstitial cells of Cajal, pacemaker cell, Pyungwi-san, traditional herbal medicine, gastrointestinal tract

(6) Journal of Pharmacopuncture, Vol. 16, No.2, pp.7~14, 2013

Review of Cervi Cornu Parvum Pharmacopuncture in Korean Medicine

Dong-Jin Lee, Min Hwangbo, Kang Kwon, Hyung-Sik Seo*

* Corresponding Author's Affiliation: Department of Ophthalmology, Otolaryngology and Dermatology, Pusan National University Korean Medicine Hospital, Yangsan, Korea.


Objective: The endpoint of this review is to investigate existing studies of Cervi cornu parvum (CCP) pharmacopuncture within Korean medicine journals in order to present a better research method in the future. Methods: We searched all the papers through six Korean electrical databases that included the title of "Cervi cornu parvum pharmacopuncture" or "Cervi cornu parvum aqua-acupuncture". Articles that had been published until December 2012 were largely divided into experimental studies and clinical studies.

Results: Fifty-three (53) experimental studies and six clinical studies were found. The number of published articles has been constantly increasing. Many of the experimental studies demonstrated anti-inflammatory effects for arthritis, and most of the clinical studies dealt with musculoskeletal problems.

Conclusion: Various therapeutically significant effects of the CCP pharmacopuncture have been found through this review; however, more systematic clinical studies on the CCP pharmacopuncture seem to be necessary to substantially support its clinical effects.

Keywords: aqua-acupuncture, Cervi, deer antler, Korean medicine, pharmacopuncture, review