Biological sciences topic list of research papers
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Spectrum of mitochondrial genomic variation and associated clinical presentation of prostate cancer in South African men2015 / John P. McCrow, Desiree C. Petersen, Melanie Louw, Eva K. F. Chan, Katherine Harmeyer, et al.
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A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity2016 / Rowena L. Sison-Young, Volker M. Lauschke, Esther Johann, Eliane Alexandre, Sébastien Antherieu, et al.
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Trends in antibiotic resistance among major bacterial pathogens isolated from blood cultures tested at a large private laboratory network in India, 2008–2014
Summary Objective There have been no long-term studies on trends in antibiotic resistance (ABR) on a national scale in India. Using a private laboratory network, the ABR patterns of organisms most commonly associated with...
2016 / Sumanth Gandra, Nestor Mojica, Eili Y. Klein, Ashvin Ashok, Vidya Nerurkar, et al. -
Transcriptomic and functional resources for the small hive beetle Aethina tumida, a worldwide parasite of honey bees
Abstract The small hive beetle (SHB), Aethina tumida, is a major pest of managed honey bee (Apis mellifera) colonies in the United States and Australia, and an emergent threat in Europe. While strong honey bee colonies generally keep SHB populations ...
2016 / Matthew R. Tarver, Qiang Huang, Lilia de Guzman, Tom Rinderer, Beth Holloway, et al. -
Territorial raven pairs are sensitive to structural changes in simulated acoustic displays of conspecifics
Human language involves combining items into meaningful, syntactically structured wholes. The evolutionary origin of syntactic abilities has been investigated by testing pattern perception capacities in nonhuman animals. New World primates can respond...
2016 / Stephan A. Reber, Markus Boeckle, Georgine Szipl, Judith Janisch, Thomas Bugnyar, et al. -
Knock-down of pantothenate kinase 2 severely affects the development of the nervous and vascular system in zebrafish, providing new insights into PKAN disease
ABSTRACT Pantothenate Kinase Associated Neurodegeneration (PKAN) is an autosomal recessive disorder with mutations in the pantothenate kinase 2 gene (PANK2), encoding an essential enzyme for Coenzyme A (CoA) biosynthesis. The molecular connection...
2015 / Daniela Zizioli, Natascia Tiso, Adele Guglielmi, Claudia Saraceno, Giorgia Busolin, et al. -
Evaluation of E1-Mutant Adenoviruses as Conditionally Replicating Agents for Cancer Therapy2002 / J Howe
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Establishment of induced pluripotent stem cell (iPSC) line from an 84-year old patient with late onset Alzheimer's disease (LOAD)
Abstract Peripheral blood mononuclear cells (PBMCs) were collected from a clinically characterised 84-year old male with late onset Alzheimer's disease (LOAD). The PMBCs were reprogrammed with the human OSKM transcription factors using the...
2016 / Zsuzsanna Táncos, Eszter Varga, Eszter Kovács, András Dinnyés, Julianna Kobolák -
MAPK kinase signalling dynamics regulate cell fate decisions and drug resistance
The RAS/RAF/MEK/MAPK kinase pathway has been extensively studied for more than 25 years, yet we continue to be puzzled by its intricate dynamic control and plasticity. Different spatiotemporal MAPK dynamics bring about distinct cell fate decisions in normal vs...
2016 / Nora Rauch, Oleksii S Rukhlenko, Walter Kolch, Boris N Kholodenko -
BCL11A Haploinsufficiency Causes an Intellectual Disability Syndrome and Dysregulates Transcription
Intellectual disability (ID) is a common condition with considerable genetic heterogeneity. Next-generation sequencing of large cohorts has identified an increasing number of genes implicated in ID, but their roles in neurodevelopment remain largely unexplored....
2016 / Cristina Dias, Sara B. Estruch, Sarah A. Graham, Jeremy McRae, Stephen J. Sawiak, et al. -
Quorum sensing communication between bacteria and human cells: signals, targets, and functions2014 / Angelika Holm, Elena Vikström
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Effects of geolocators on hatching success, return rates, breeding movements, and change in body mass in 16 species of Arctic-breeding shorebirds2016 / Emily L. Weiser, Richard B. Lanctot, Stephen C. Brown, José A. Alves, Phil F. Battley, et al.
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A biphasic effect of TNF-α in regulation of the Keap1/Nrf2 pathway in cardiomyocytes
Abstract Antagonizing TNF-α signaling attenuates chronic inflammatory disease, but is associated with adverse effects on the cardiovascular system. Therefore the impact of TNF-α on basal control of redox signaling events needs to be understand in...
2016 / Gobinath Shanmugam, Madhusudhanan Narasimhan, Ramasamy Sakthivel, Rajesh Kumar R, Christopher Davidson, et al. -
Maintenance of glutathione levels and its importance in epigenetic regulation2014 / José L. GarcÃa-Giménez, Federico V. Pallardó
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New Perspectives on Ancient Granulomas2013 / Dov L. Boros
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Top-down network analysis characterizes hidden termite-termite interactions2016 / Colin Campbell, Laura Russo, Alessandra Marins, Og DeSouza, Karsten Schönrogge, et al.
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Pallasite paleomagnetism: Quiescence of a core dynamo
Abstract Recent paleomagnetic studies of two Main Group pallasites, the Imilac and Esquel, have found evidence for a strong, late-stage magnetic field on the parent body. It has been hypothesized that this magnetic field was generated by a core...
2016 / Claire I.O. Nichols, James F.J. Bryson, Julia Herrero-Albillos, Florian Kronast, Francis Nimmo, et al. -
Herpes simplex encephalitis is linked with selective mitochondrial damage; a post-mortem and in vitro study2016 / Małgorzata Wnęk, Lorenzo Ressel, Emanuele Ricci, Carmen Rodriguez-Martinez, Julio Cesar Villalvazo Guerrero, et al.
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Whole-body DHA synthesis-secretion kinetics from plasma eicosapentaenoic acid and alpha-linolenic acid in the free-living rat
Abstract Whole body docosahexaenoic acid (DHA, 22:6n-3) synthesis from α-linolenic acid (ALA, 18:3n-3) is considered to be very low, however, the daily synthesis-secretion of DHA may be sufficient to supply the adult brain. The current study aims to ...
2016 / Adam H. Metherel, Anthony F. Domenichiello, Alex P. Kitson, Kathryn E. Hopperton, Richard P. Bazinet -
Elements of lentiviral vector design toward gene therapy for treating mucopolysaccharidosis I
Abstract Mucopolysaccharidosis type I (MPS I) is a lysosomal disease caused by α-l-iduronidase (IDUA) deficiency and accumulation of glycosaminoglycans (GAG). Lentiviral vector encoding correct IDUA cDNA could be used for treating MPS I. To optimize ...
2016 / Li Ou, Michael J. Przybilla, Brenda L. Koniar, Chester B. Whitley