Biological sciences topic list of research papers
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Quantitative secretome analysis reveals the interactions between epithelia and tumor cells by in vitro modulating colon cancer microenvironment
Abstract In tumor microenvironment, interactions among multiple cell types are critical for cancer progression. Secreted proteins are responsible for crosstalk among these cells within tumor microenvironment. To elucidate the interactions of tumor...
2013 / Xiao Zeng, Pengbo Yang, Bing Chen, Xuewen Jin, Yuling Liu, et al. -
Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function2012 / Dana B. Hancock, María Soler Artigas, Sina A. Gharib, Amanda Henry, Ani Manichaikul, et al.
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Active site cysteine-null glyceraldehyde-3-phosphate dehydrogenase (GAPDH) rescues nitric oxide-induced cell death
Abstract Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a homotetrameric enzyme involved in a key step of glycolysis, also has a role in mediating cell death under nitrosative stress. Our previous reports suggest that nitric oxide-induced...
2015 / Takeya Kubo, Hidemitsu Nakajima, Masatoshi Nakatsuji, Masanori Itakura, Akihiro Kaneshige, et al. -
GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells
Summary Advances in the scalable production of blood cells from induced pluripotent stem cells (iPSCs) open prospects for the clinical translation of de novo generated blood products, and evoke the need for preclinical evaluation of their efficacy,...
2016 / Saritha S. D'Souza, John Maufort, Akhilesh Kumar, Jiuchun Zhang, Kimberley Smuga-Otto, et al. -
Evidence of vertical transmission and tissue tropism of Streptococcosis from naturally infected red tilapia (Oreochromis spp.)
Abstract Streptococcosis is a highly problematic disease in the aquaculture of freshwater fishes, especially for tilapia. The possibility of vertical transmission of streptococcosis and the pattern of tissue tropism of this pathogen in various...
2016 / Padmaja Jayaprasad Pradeep, Rungkarn Suebsing, Sarawut Sirthammajak, Jantana Kampeera, Sarocha Jitrakorn, et al. -
Regenerative biosensor chips based on switchable mutants of avidin—A systematic study
Abstract Biotinylated bait molecules can be immobilized on biotinylated sensor chips by formation of biotin–avidin–biotin bridges which are very stable when using wild-type (strept)avidin. Stable immobilization of biotinylated baits is important for ...
2016 / Dominik Zauner, Barbara Taskinen, Daniel Eichinger, Clemens Flattinger, Bianca Ruttmann, et al. -
Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling
Summary Modeling of neurological diseases using induced pluripotent stem cells (iPSCs) derived from the somatic cells of patients has provided a means of elucidating pathogenic mechanisms and performing drug screening. T cells are an ideal source of ...
2016 / Takuya Matsumoto, Koki Fujimori, Tomoko Andoh-Noda, Takayuki Ando, Naoko Kuzumaki, et al. -
Helicobacter pylori upregulates Nanog and Oct4 via Wnt/β-catenin signaling pathway to promote cancer stem cell-like properties in human gastric cancer
Abstract Helicobacter pylori (H. pylori) infection is considered a major risk factor for gastric cancer. CagA behaves as a major bacterial oncoprotein playing a key role in H. pylori-induced tumorigenesis. Cancer stem cells...
2016 / Xin Yong, Bo Tang, Yu-Feng Xiao, Rui Xie, Yong Qin, et al. -
Stress enables reinforcement-elicited serotonergic consolidation of fear memory
Abstract Background Prior exposure to stress is a risk factor for developing posttraumatic stress disorder (PTSD) in response to trauma, yet the mechanisms by which this occurs are unclear. Using a rodent model of stress-based...
2015 / Michael V. Baratta, Suhasa B. Kodandaramaiah, Patrick E. Monahan, Junmei Yao, Michael D. Weber, et al. -
The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognition
Abstract Mycobacterium tuberculosis is a facultative anaerobe and its characteristic pathological hallmark, the granuloma, exhibits hypoxia in humans and in most experimental models. Thus the host and bacillary adaptation to...
2016 / Gareth Prosser, Brandenburg Julius, Norbert Reiling, Clifton Earl Barry, Robert J. Wilkinson, et al. -
Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
Summary Tools for rapid and efficient transgenesis in “safe harbor” loci in an isogenic context remain important to exploit the possibilities of human pluripotent stem cells (hPSCs). We created hPSC master cell lines suitable for FLPe...
2015 / Laura Ordovás, Ruben Boon, Mariaelena Pistoni, Yemiao Chen, Esther Wolfs, et al. -
Paeoniflorin selectively inhibits LPS-provoked B-cell function
Abstract B cells are important in the development of autoimmune disorders through mechanisms involving dysregulated polyclonal B-cell activation, production of pathogenic antibodies, and targeting which reduces inflammation and tissue damage...
2015 / Jie Zhang, Huidan Li, Rongfen Huo, Tianhang Zhai, Haichuan Li, et al. -
Molecular mapping of the hybrid necrosis gene NetJingY176 in Aegilops tauschii using microsatellite markers
Abstract The rich genetic variation preserved in collections of Aegilops tauschii can be readily exploited to improve common wheat using synthetic hexaploid wheat lines. However, hybrid necrosis, which is characterized by progressive death of leaves ...
2015 / Fengbo Xue, Jun Guo, Changying Guan, Hongwei Wang, Anfei Li, et al. -
Medicinal and local food plants in the south of Alava (Basque Country, Spain)
Abstract Ethnobotanical relevance Medicinal and food plants in the Basque Country are an integral part of a fast changing culture. With a distinct tradition and language, this region of Europe provides an important example...
2015 / Rocίo Alarcόn, Manuel Pardo-de-Santayana, Caroline Priestley, Ramón Morales, Michael Heinrich -
Affinity maturation of a portable Fab–RNA module for chaperone-assisted RNA crystallography2017 / Deepak Koirala, Sandip A Shelke, Marcel Dupont, Stormy Ruiz, Saurja DasGupta, et al.
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Asphodelus fistulosus (Asphodelaceae, Asphodeloideae), a new naturalised alien species from the West Coast of South Africa
Abstract Asphodelus fistulosus or onionweed is recorded in South Africa for the first time and is the first record of an invasive member of the Asphodelaceae in the country. Only two populations of this plant have been...
2011 / J.S. Boatwright -
How well can in vitro data predict in vivo effects of chemicals? Rodent carcinogenicity as a case study
Abstract A recent research article by the National Center for Computational Toxicology (NCCT) (Kleinstreuer et al., 2013), indicated that high throughput screening (HTS) data from assays linked to hallmarks and presumed pathways of carcinogenesis...
2016 / Louis Anthony (Tony) Cox, Douglas A. Popken, A. Michael Kaplan, Laura M. Plunkett, Richard A. Becker -
A 26-hour system of highly sensitive whole genome sequencing for emergency management of genetic diseases2015 / Neil A. Miller, Emily G. Farrow, Margaret Gibson, Laurel K. Willig, Greyson Twist, et al.
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Effect of Bacillus sphaericus Neide on Anopheles (Diptera: Culicidae) and associated insect fauna in fish ponds in the Amazon2015 / Francisco Augusto da Silva Ferreira, Adriano Nobre Arcos, Raquel Telles de Moreira Sampaio, Ilea Brandão Rodrigues, Wanderli Pedro Tadei
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Symbiosis and microbiome flexibility in calcifying benthic foraminifera of the Great Barrier Reef2017 / Martina Prazeres, Tracy Ainsworth, T. Edward Roberts, John M. Pandolfi, William Leggat