Biological sciences topic list of research papers
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Transcription factors of Schizophyllum commune involved in mushroom formation and modulation of vegetative growth2017 / Jordi F. Pelkmans, Mohini B. Patil, Thies Gehrmann, Marcel J. T. Reinders, Han A. B. Wösten, et al.
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Preferential M2 macrophages contribute to fibrosis in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease
Abstract IgG4-related dacryoadenitis and sialoadenitis (IgG4-DS) is characterized by bilateral swelling of glandular tissues with extensive fibrosis, and is immunologically considered a Th2-predominant disease. Recent studies reported that...
2014 / Sachiko Furukawa, Masafumi Moriyama, Akihiko Tanaka, Takashi Maehara, Hiroto Tsuboi, et al. -
The mixed lineage kinase-3 inhibitor URMC-099 improves therapeutic outcomes for long-acting antiretroviral therapy
Abstract During studies to extend the half-life of crystalline nanoformulated antiretroviral therapy (nanoART) the mixed lineage kinase-3 inhibitor URMC-099, developed as an adjunctive neuroprotective agent was shown to facilitate antiviral...
2015 / Gang Zhang, Dongwei Guo, Prasanta K. Dash, Mariluz Araínga, Jayme L. Wiederin, et al. -
The ocean sampling day consortium2015 / Anna Kopf, Mesude Bicak, Renzo Kottmann, Julia Schnetzer, Ivaylo Kostadinov, et al.
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On-column trypsinization allows for re-use of matrix in modified multiplexed inhibitor beads assay
Abstract The Multiplexed Inhibitor Bead (MIB) assay is a previously published quantitative proteomic MS-based approach to study cellular kinomes. A rather extensive procedure, need for multiple custom-made kinase inhibitors and an inability to...
2017 / Voin Petrovic, Camilla Olaisen, Animesh Sharma, Anala Nepal, Steffen Bugge, et al. -
MicroRNA-containing extracellular vesicles released from endothelial colony-forming cells modulate angiogenesis during ischaemic retinopathy2017 / Margaret Dellett, Eoin D. Brown, Jasenka Guduric-Fuchs, Anna O'Connor, Alan W. Stitt, et al.
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The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease2017 / Francesca Farina, Emmanuel Lambert, Lucie Commeau, François-Xavier Lejeune, Nathalie Roudier, et al.
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Expansion of myeloid-derived suppressor cells with aging in the bone marrow of mice through a NF-κB-dependent mechanism2017 / Rafael R. Flores, Cheryl L. Clauson, Joonseok Cho, Byeong-Chel Lee, Sara J. McGowan, et al.
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Trypanosoma cruzi nucleoside triphosphate diphosphohydrolase 1 (TcNTPDase-1) biochemical characterization, immunolocalization and possible role in host cell adhesion
Abstract Previous work has suggested that Trypanosoma cruzi diphosphohydrolase 1 (TcNTPDase-1) may be involved in the infection of mammalian cells and serve as a potential target for rational drug design. In this work, we produced recombinant...
2013 / Christiane Mariotini-Moura, Matheus Silva e Bastos, Felipe Freitas de Castro, Mellina Lanna Trindade, Raphael de Souza Vasconcellos, et al. -
Biological, ecological, conservation and legal information for all species and subspecies of Australian bird2015 / Stephen T. Garnett, Daisy E. Duursma, Glenn Ehmke, Patrick-Jean Guay, Alistair Stewart, et al.
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Inhibition of miRNA-212/132 improves the reprogramming of fibroblasts into induced pluripotent stem cells by de-repressing important epigenetic remodelling factors
Abstract MicroRNAs (miRNAs) repeatedly have been demonstrated to play important roles in the generation of induced pluripotent stem cells (iPSCs). To further elucidate the molecular mechanisms underlying transcription factor-mediated reprogramming...
2017 / Nils Pfaff, Steffi Liebhaber, Selina Möbus, Abbas Beh-Pajooh, Jan Fiedler, et al. -
Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants2017 / Reka Nagy, Thibaud S. Boutin, Jonathan Marten, Jennifer E. Huffman, Shona M. Kerr, et al.
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Phenotypic convergence of artificially reared and wild trout is mediated by shape plasticity2017 / Jorge Ruben Sánchez-González, Alfredo G. Nicieza
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Correction: peptidoglycan: a post-genomic analysis2014 / Caroline Cayrou, Bernard Henrissat, Philippe Gouret, Pierre Pontarotti, Michel Drancourt
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Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells
Summary Familial hypercholesterolemia (FH) causes elevation of low-density lipoprotein cholesterol (LDL-C) in blood and carries an increased risk of early-onset cardiovascular disease. A caveat for exploration of new therapies for FH is the lack of...
2017 / Jiayin Yang, Yu Wang, Ting Zhou, Lai-Yung Wong, Xiao-Yu Tian, et al. -
Non-canonical WNT/PCP signalling in cancer: Fzd6 takes centre stage2017 / G Corda, A Sala
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Brain State Dependence of Hippocampal Subthreshold Activity in Awake Mice
Summary Monitoring the membrane potential of individual neurons has uncovered how single-cell properties contribute to network processing across different brain states in neocortex. In contrast, the subthreshold modulation of hippocampal neurons by...
2017 / Brad K. Hulse, Evgueniy V. Lubenov, Athanassios G. Siapas -
Significant under expression of the DosR regulon in M. tuberculosis complex Lineage 6 in sputum
Abstract Mycobacterium africanum lineage (L) 6 is an important pathogen in West Africa, causing up to 40% of pulmonary tuberculosis (TB). The biology underlying the clinical differences between M. africanum and M. tuberculosis...
2017 / Boatema Ofori-Anyinam, Gregory Dolganov, Tran Van, J. Lucian Davis, Nicholas D. Walter, et al. -
Remote ischemic preconditioning differentially attenuates post-ischemic cardiac arrhythmia in streptozotocin-induced diabetic versus nondiabetic rats2017 / Zhaoyang Hu, Mou Chen, Ping Zhang, Jin Liu, Geoffrey W. Abbott
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Sphingosine 1-phosphate receptor 2 (S1P2) attenuates reactive oxygen species formation and inhibits cell death: implications for otoprotective therapy2016 / Deron R. Herr, Marie J. Y. Reolo, Yee Xin Peh, Wei Wang, Chang-Wook Lee, et al.