Biological sciences topic list of research papers
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Mechanical recruitment of N- and C-crosslinks in collagen type I
Abstract Collagen type I is an extracellular matrix protein found in connective tissues such as tendon, ligament, bone, skin, and the cornea of the eyes, where it functions to provide tensile strength; it also serves as a scaffold for cells and...
2013 / Albert L. Kwansa, Raffaella De Vita, Joseph W. Freeman -
Identification of targets of miR-200b by a SILAC-based quantitative proteomic approach
Abstract miRNAs regulate gene expression by binding to cognate mRNAs causing mRNA degradation or translational repression. Mass spectrometry-based proteomic analysis is being widely used to identify miRNA targets. The miR-200b miRNA cluster is often ...
2014 / Arivusudar Marimuthu, Tai-Chung Huang, Lakshmi Dhevi N. Selvan, Santosh Renuse, Raja Sekhar Nirujogi, et al. -
High expression of Fatty Acid-Binding Protein 5 promotes cell growth and metastatic potential of colorectal cancer cells2016 / Koichiro Kawaguchi, Shogo Senga, Chiaki Kubota, Yuki Kawamura, Youqiang Ke, et al.
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Colistin resistance in non-fermenting Gram-negative bacilli in a university hospital2016 / Silvana Oliveira dos Santos, Sthefanine Martins La Rocca, Rosmari Hörner
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DIP1 plays an antiviral role against DCV infection in Drosophila melanogaster
Abstract Disconnected Interacting Protein 1 (DIP1) is a dsRNA-binding protein that participates in a wide range of cellular processes. Whether DIP1 is involved in innate immunity remains unclear. Here, DIP1 was found to play an antiviral role in S2...
2015 / Qi Zhang, Liqin Zhang, Xinlei Gao, Shuishui Qi, Zhaoxia Chang, et al. -
Gain-of-Function Mutations in ZIC1 Are Associated with Coronal Craniosynostosis and Learning Disability
Human ZIC1 (zinc finger protein of cerebellum 1), one of five homologs of the Drosophila pair-rule gene odd-paired, encodes a transcription factor previously implicated in vertebrate brain development. Heterozygous deletions of ZIC1 and its nearby paralog ZIC4 on...
2015 / Stephen R.F. Twigg, Jennifer Forecki, Jacqueline A.C. Goos, Ivy C.A. Richardson, A. Jeannette M. Hoogeboom, et al. -
A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD
Abstract Spinocerebellar ataxia type 3 (SCA3/MJD) is a neurodegenerative disease triggered by the expansion of CAG repeats in the ATXN3 gene. Here, we report the generation of the first humanized ataxin-3 knock-in mouse model (Ki91), which provides...
2014 / Pawel M. Switonski, Wojciech J. Szlachcic, Wlodzimierz J. Krzyzosiak, Maciej Figiel -
AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma
Summary The Hedgehog (Hh) pathway regulates cell differentiation and proliferation during development by controlling the Gli transcription factors. Cell fate decisions and progression toward organ and tissue maturity must be coordinated, and how an...
2015 / Yen-Hsing Li, Jia Luo, Yung-Yi C. Mosley, Victoria E. Hedrick, Lake N. Paul, et al. -
Stem-Cell-like Properties and Epithelial Plasticity Arise as Stable Traits after Transient Twist1 Activation
Summary Master regulators of the epithelial-mesenchymal transition such as Twist1 and Snail1 have been implicated in invasiveness and the generation of cancer stem cells, but their persistent activity inhibits stem-cell-like properties and the...
2015 / Johanna M. Schmidt, Elena Panzilius, Harald S. Bartsch, Martin Irmler, Johannes Beckers, et al. -
Wild jackdaws’ reproductive success and their offspring’s stress hormones are connected to provisioning rate and brood size, not to parental neophobia
Abstract Many species show individual variation in neophobia and stress hormones, but the causes and consequences of this variation in the wild are unclear. Variation in neophobia levels could affect the number of offspring animals produce, and more ...
2016 / Alison L. Greggor, Karen A. Spencer, Nicola S. Clayton, Alex Thornton -
Erythropoietin reduces storage lesions and decreases apoptosis indices in blood bank red blood cells
Abstract Background Recent evidence shows a selective destruction of the youngest circulating red blood cells (neocytolysis) trigged by a drop in erythropoietin levels. Objective ...
2015 / Oscar Andrés Penuela, Fernando Palomino, Lina Andrea Gómez -
Environmental factors influencing multiple sclerosis in Latin America2017 / Jorge Correale, Mauricio F Farez, María Inés Gaitán
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Fine mapping of a QTL on bovine chromosome 6 using imputed full sequence data suggests a key role for the group-specific component (GC) gene in clinical mastitis and milk production2016 / Hanne Gro Olsen, Tim Martin Knutsen, Anna M. Lewandowska-Sabat, Harald Grove, Torfinn Nome, et al.
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miR-19a contributes to gefitinib resistance and epithelial mesenchymal transition in non-small cell lung cancer cells by targeting c-Met2017 / Xiaonian Cao, Senyan Lai, Fayong Hu, Guodong Li, Guihua Wang, et al.
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The Type Ia Supernova Color–Magnitude Relation and Host Galaxy Dust: A Simple Hierarchical Bayesian Model2017 / Kaisey S. Mandel, Daniel M. Scolnic, Hikmatali Shariff, Ryan J. Foley, Robert P. Kirshner
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Cdc20 directs proteasome-mediated degradation of the tumor suppressor SMAR1 in higher grades of cancer through the anaphase promoting complex2017 / Debasish Paul, Suvankar Ghorai, U S Dinesh, Praveenkumar Shetty, Samit Chattopadhyay, et al.
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A systematic evaluation of nucleotide properties for CRISPR sgRNA design2017 / Pei Fen Kuan, Scott Powers, Shuyao He, Kaiqiao Li, Xiaoyu Zhao, et al.
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The Integrated Genomic Architecture and Evolution of Dental Divergence in East African Cichlid Fishes ( Haplochromis chilotes x H. nyererei )2017 / C. Darrin Hulsey, Gonzalo Machado-Schiaffino, Lara Keicher, Diego Ellis-Soto, Frederico Henning, et al.
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Distinct sets of locomotor modules control the speed and modes of human locomotion2016 / Hikaru Yokoyama, Tetsuya Ogawa, Noritaka Kawashima, Masahiro Shinya, Kimitaka Nakazawa
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Variation in growth rates of branching corals along Australia’s Great Barrier Reef2017 / Kristen D. Anderson, Neal E. Cantin, Scott F. Heron, Chiara Pisapia, Morgan S. Pratchett