Biological sciences topic list of research papers
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PPARγ Controls Dectin-1 Expression Required for Host Antifungal Defense against Candida albicans2010 / Amandine Galès, Annabelle Conduché, José Bernad, Lise Lefevre, David Olagnier, et al.
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Genetic model selection for a case–control study and a meta-analysis
Abstract A case–control study often compares the prevalence of a specific disease among persons with normal alleles and persons with variant alleles, which generates an odds ratio (OR). The most common type of allele variation, single-nucleotide...
2015 / Nobuyuki Horita, Takeshi Kaneko -
Efficient introgression of allelic variants by embryo-mediated editing of the bovine genome2015 / Jingwei Wei, Stefan Wagner, Dan Lu, Paul Maclean, Daniel F. Carlson, et al.
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Opioid Exacerbation of Gram-positive sepsis, induced by Gut Microbial Modulation, is Rescued by IL-17A Neutralization2015 / Jingjing Meng, Santanu Banerjee, Dan Li, Gregory M. Sindberg, Fuyuan Wang, et al.
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Unconventionally secreted effectors of two filamentous pathogens target plant salicylate biosynthesis2014 / Tingli Liu, Tianqiao Song, Xiong Zhang, Hongbo Yuan, Liming Su, et al.
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Comparison of Metabolic Pathways in Escherichia coli by Using Genetic Algorithms
Abstract In order to understand how cellular metabolism has taken its modern form, the conservation and variations between metabolic pathways were evaluated by using a genetic algorithm (GA). The GA approach considered information on the complete...
2015 / Patricia Ortegon, Augusto C. Poot-Hernández, Ernesto Perez-Rueda, Katya Rodriguez-Vazquez -
TRPA1 mediates the hypothermic action of acetaminophen2015 / Clive Gentry, David A. Andersson, Stuart Bevan
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Moral and scientific boundaries: research ethics on the Thai-Burma border2012 / M. J. Parker
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A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus2015 / Ying Wu, MyungSam Cho, David Shore, Manki Song, JungAh Choi, et al.
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Direct uptake of Antagomirs and efficient knockdown of miRNA in primary B and T lymphocytes
Abstract Depending on their physiological expression level, microRNAs (miRNA) address different target genes, thus have different biological functions. To identify these, the physiological expression has to be blocked. Here, we describe the use of...
2015 / Claudia Haftmann, René Riedel, Martina Porstner, Jürgen Wittmann, Hyun-Dong Chang, et al. -
Association of Versican (VCAN) gene polymorphisms rs251124 and rs2287926 (G428D), with intracranial aneurysm
Abstract Intracranial aneurysm (IA) accounts for 85% of Subarachnoid Hemorrhage (SAH) and is mainly caused due to the weakening of arterial wall. The structural integrity of the intracranial arteries is mainly influenced by the extracellular matrix...
2014 / Sanish Sathyan, Linda V. Koshy, Shabeesh Balan, H.V. Easwer, S. Premkumar, et al. -
Expression of CRISPR/Cas single guide RNAs using small tRNA promoters2015 / A. L. Mefferd, A. V. R. Kornepati, H. P. Bogerd, E. M. Kennedy, B. R. Cullen
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Injury-induced immune responses in Hydra
Abstract The impact of injury-induced immune responses on animal regenerative processes is highly variable, positive or negative depending on the context. This likely reflects the complexity of the innate immune system that behaves as a sentinel in...
2014 / Yvan Wenger, Wanda Buzgariu, Silke Reiter, Brigitte Galliot -
Is Cancer a Genetic Disease or a Metabolic Disease?2015 / David S. Wishart
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A low cost fermentation medium for potential fibrinolytic enzyme production by a newly isolated marine bacterium, Shewanella sp. IND20
Abstract Agro-residues were used as the substrate for the production of fibrinolytic enzyme in solid state fermentation. In this study, two-level full factorial design (25) and response surface methodology were applied to optimize a fermentation...
2015 / P. Vijayaraghavan, S.G. Prakash Vincent -
Reproductive and developmental outcomes, and influence on maternal and offspring tissue mineral concentrations, of (−)-epicatechin, (+)-catechin, and rutin ingestion prior to, and during pregnancy and lactation in C57BL/6J mice
Abstract Maternal nutrition can have a significant effect on developmental processes during pregnancy and lactation. While certain flavonoids have been postulated to be beneficial for health, little is known about the effects of ingestion during...
2015 / Mary N.R. Lesser, Carl L. Keen, Louise Lanoue -
Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor β-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells
Abstract Transforming growth factor β-activated kinase 1 (TAK1) is critical for survival of many KRAS mutated colorectal cancer cells, and TAK1 inhibition with 5Z-7-oxozeaenol has been associated with oxidative stress leading to tumor cell killing....
2015 / Jennifer E. Hrabe, Brianne R. O’Leary, Melissa A. Fath, Samuel N. Rodman, Anna M. Button, et al. -
ADIPOQ and ADIPOR2 gene polymorphisms: association with overweight/obesity in Mexican children
Abstract Background ENSANUT 2012 showed a combined prevalence of overweight and obesity of 34.4% in Mexican children. Single nucleotide polymorphisms (SNPs) of the ADIPOQ and ADIPOR2 genes have been reported in many populations,...
2015 / José de Jesús Peralta Romero, Roberto Karam Araujo, Ana Isabel Burguete García, Barbara Ixchel Estrada Velasco, Claudia López Islas, et al. -
Expression and purification of soluble single-chain Fv against human fibroblast growth factor receptor 3 fused with Sumo tag in Escherichia coli
Abstract Background Overexpression or mutated activation of Fibroblast growth factor receptor 3 (FGFR3) is involved in the pathogenesis of many tumors. More and more studies focus on the potential usage of therapeutic antibodies...
2015 / Zixuan Liu, Jizhou Zhang, Hongqiong Fan, Ruofeng Yin, Zhong Zheng, et al. -
Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in Mice
Background & Aims Perturbations in pancreatic ductal bicarbonate secretion cause chronic pancreatitis. The physiologic mechanism of ductal secretion is known, but its transcriptional control is not. We determine the role of the transcription...
2015 / Mark J. Ferreira, Lindsay B. McKenna, Jia Zhang, Maximilian Reichert, Basil Bakir, et al.