Basic medicine topic list of research papers
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The Impact of Exercising During Haemodialysis on Blood Pressure, Markers of Cardiac Injury and Systemic Inflammation - Preliminary Results of a Pilot Study2015 / Maurice Dungey, Nicolette C. Bishop, Hannah M.L. Young, James O. Burton, Alice C. Smith
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Altered protease and antiprotease balance during a COPD exacerbation contributes to mucus obstruction2015 / Shashi Chillappagari, Jenni Preuss, Sebastian Licht, Christian Müller, Poornima Mahavadi, et al.
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Food for thought: The role of nutrition in the microbiota-gut–brain axis
Summary Recent research has provided strong evidence for the role of the commensal gut microbiota in brain function and behaviour. Many potential pathways are involved in this bidirectional communication between the gut microbiota and the brain such ...
2016 / Clara Seira Oriach, Ruairi C. Robertson, Catherine Stanton, John F. Cryan, Timothy G. Dinan -
Towards a functional definition of the mitochondrial human proteome
Abstract The mitochondrial human proteome project (mt-HPP) was initiated by the Italian HPP group as a part of both the chromosome-centric initiative (C-HPP) and the biology and disease driven initiative (B/D-HPP). In recent years several reports...
2016 / Mauro Fasano, Tiziana Alberio, Mohan Babu, Emma Lundberg, Andrea Urbani -
Stem Cell Therapy for Heart Failure: Ensuring Regenerative Proficiency
Abstract Patient-derived stem cells enable promising regenerative strategies, but display heterogenous cardiac reparative proficiency, leading to unpredictable therapeutic outcomes impeding practice adoption. Means to establish and certify the...
2016 / Andre Terzic, Atta Behfar -
Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice2015 / Youfang Chen, Jianfeng Du, Yu Tina Zhao, Ling Zhang, Guorong Lv, et al.
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Application of microfluidic technologies to the quantification and manipulation of sperm
Abstract With respect to male fertility, sperm play a crucial role in the whole process of fertilization. Many technologies for manipulating sperm have been developed over the past few decades and these have focused on counting and sorting sperm....
2014 / Vincent F.S. Tsai, Hong-Chiang Chang, Ju-Ton Hsieh, Andrew M. Wo -
Left ventricular diastolic dysfunction in Nrf2 knock out mice is associated with cardiac hypertrophy, decreased expression of SERCA2a, and preserved endothelial function
Abstract Increased production of reactive oxygen species and failure of the antioxidant defense system are considered to play a central role in the pathogenesis of cardiovascular disease. The transcription factor nuclear factor (erythroid-derived...
2015 / Ralf Erkens, Christian M. Kramer, Wiebke Lückstädt, Christina Panknin, Lisann Krause, et al. -
Phosphodiesterase inhibitor KMUP-3 displays cardioprotection via protein kinase G and increases cardiac output via G-protein-coupled receptor agonist activity and Ca2+ sensitization
Abstract KMUP-3 (7-{2-[4-(4-nitrobenzene) piperazinyl]ethyl}-1, 3-dimethylxanthine) displays cardioprotection and increases cardiac output, and is suggested to increase cardiac performance and improve myocardial infarction. To determine whether...
2016 / Chung-Pin Liu, Jwu-Lai Yeh, Shu-Fen Liou, Bin-Nan Wu, Ing-Jun Chen -
The Sperm Chromatin Structure Assay (SCSA®) and other sperm DNA fragmentation tests for evaluation of sperm nuclear DNA integrity as related to fertility
Abstract Thirty-five years ago the pioneering paper in Science (240:1131) on the relationship between sperm DNA integrity and pregnancy outcome was featured as the cover issue showing a fluorescence photomicrograph of red and green stained sperm....
2016 / Donald P. Evenson -
Injury caused by airbag VS. injuries associated with airbag deploys2014 / Popa M.F., Parlica I.
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Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice2016 / Franziska Werner, Baktybek Kojonazarov, Birgit Gaßner, Marco Abeßer, Kai Schuh, et al.
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Sleep apnoea2016 / Jonathan C. Jun, Swati Chopra, Alan R. Schwartz
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Methylglyoxal-Induced Endothelial Cell Loss and Inflammation Contribute to the Development of Diabetic Cardiomyopathy2016 / Branka Vulesevic, Brian McNeill, Ferdinando Giacco, Kay Maeda, Nick J. R. Blackburn, et al.
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Upregulated Expression of A20 on Monocytes is Associated With Increased Severity of Acute-on-Chronic Hepatitis B Liver Failure2015 / Yonghong Guo, Yu He, Ying Zhang, Yun Zhou, Yuan Qin, et al.
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EEG in non-clinical drug safety assessments: Current and emerging considerations
Abstract Electroencephalogram (EEG) data in nonclinical species can play a critical role in the successful evaluation of a compound during drug development, particularly in the evaluation of seizure potential and for monitoring changes in sleep....
2016 / Simon Authier, Marcus S. Delatte, Mary-Jeanne Kallman, Joanne Stevens, Carrie Markgraf -
Rapid atrial pacing induces myocardial fibrosis by down-regulating Smad7 via microRNA-21 in rabbit2016 / Xuyu He, Kunyi Zhang, Xiuren Gao, Liwen Li, Hong Tan, et al.
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Red cell distribution width (RDW) correlates with markers of diastolic dysfunction in patients with impaired left ventricular systolic function
Abstract Objective Red-cell distribution width (RDW) has been identified as a novel prognostic marker in a heterogeneous group of heart failure patients. In this group, diastolic dysfunction is associated with worse outcome. As the ...
2015 / Fadi T. Alattar, Nashat B. Imran, Pooja Patel, Saad Usmani, Fayez E. Shamoon -
Pitx2c increases in atrial myocytes from chronic atrial fibrillation patients enhancing I Ks and decreasing I Ca,L2016 / Marta Pérez-Hernández, Marcos Matamoros, Adriana Barana, Irene Amorós, Ricardo Gómez, et al.
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Balancing idealism with realism to safeguard the welfare of patients: The importance of Heart Team led decision-making in patients with complex coronary artery disease2016 / Vasim Farooq, Carlo Di Mario, Patrick W. Serruys