Basic medicine topic list of research papers
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Luteinizing hormone and follicle stimulating hormone synergy: A review of role in controlled ovarian hyper-stimulation2014 / GottumukkalaAchyuta Rama Raju, Rahul Chavan, Mamata Deenadayal, Mirudhubashini Govindarajan, Devika Gunasheela, et al.
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The human relevant potency threshold: Reducing uncertainty by human calibration of cumulative risk assessments
Abstract The 2008 National Research Council report “Phthalates and Cumulative Risk Assessment: Tasks Ahead,” rejected the underlying premises of TEQ-like approaches – e.g., chemicals are true congeners; are metabolized and detoxified similarly;...
2011 / C.J. Borgert, E.V. Sargent, G. Casella, D.R. Dietrich, L.S. McCarty, et al. -
Overview of the marmoset as a model in nonclinical development of pharmaceutical products
Abstract Callithrix jacchus (common marmoset) is one of the more primitive non-human primate species and is used widely in fundamental biology, pharmacology and toxicology studies. Marmosets breed well in captivity with good...
2010 / Antonia Orsi, Daryl Rees, Isabella Andreini, Silvana Venturella, Serena Cinelli, et al. -
N‐acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure2016 / Beverly Giam, Po‐Yin Chu, Sanjaya Kuruppu, A. Ian Smith, Duncan Horlock, et al.
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Glucagon-like peptide-1 (GLP-1) and protective effects in cardiovascular disease: a new therapeutic approach for myocardial protection2013 / Ting C Zhao
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Mitochondrial inhibitor as a new class of insulin sensitizer
Abstract Insulin resistance is a major risk factor for type 2 diabetes. AMP-activated protein kinase (AMPK) is a drug target in the improvement of insulin sensitivity. Several insulin-sensitizing medicines are able to activate AMPK through...
2012 / Yong Zhang, Jianping Ye -
A review of Omics research in acupuncture: The relevance and future prospects for understanding the nature of meridians and acupoints
Abstract Relevance Acupuncture is an intrinsic part of traditional Chinese medicine. The current understanding of the acupuncture meridian system, acupoints and the potential utilizing Omics technologies are summarized in this...
2012 / Jun Jia, Yan Yu, Jia-Hui Deng, Nicola Robinson, Mark Bovey, et al. -
Summary of the 2012 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevations. Prepared by the Czech Society of Cardiology☆2012 / Petr Widimský, Petr Kala, Richard Rokyta
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High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels2012 / Taiga Ichinomiya, Sungsam Cho, Ushio Higashijima, Shuhei Matsumoto, Takuji Maekawa, et al.
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Coconut kernel protein in diet protects the heart by beneficially modulating endothelial nitric oxide synthase, tumor necrosis factor-alpha, and nuclear factor-kappaB expressions in experimental myocardial infarction
Abstract Previous studies conducted in our laboratory revealed that coconut kernel protein has a significant cardioprotective effect on isoproterenol-induced myocardial infarction in rats. In the present study, we explored the possible protective...
2013 / Suganthi Remya, Anitha Madhusoodhanan Chikku, Raveendran Saraswathy Renjith, Sakunthala Arunima, Thankappan Rajamohan -
Cellular bases for human atrial fibrillation
Atrial fibrillation (AF) causes substantial morbidity and mortality. It may be triggered and sustained by either reentrant or nonreentrant electrical activity. Human atrial cellular refractory period is shortened in chronic AF, likely aiding reentry. The ionic and ...
2008 / Antony J. Workman, Kathleen A. Kane, Andrew C. Rankin -
A public–private consortium advances cardiac safety evaluation: Achievements of the HESI Cardiac Safety Technical Committee
Abstract Introduction: The evaluation of cardiovascular side-effects is a critical element in the development of all new drugs and chemicals. Cardiac safety issues are a major cause of attrition and withdrawal due to adverse...
2013 / Jennifer B. Pierson, Brian R. Berridge, Marjory B. Brooks, Kevin Dreher, John Koerner, et al. -
Role of PGE2 in Asthma and Nonasthmatic Eosinophilic Bronchitis2012 / Beatriz Sastre, Victoria del Pozo
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Fatty Acid Oxidation and Cardiovascular Risk during Menopause: A Mitochondrial Connection?2012 / Paulo J. Oliveira, Rui A. Carvalho, Piero Portincasa, Leonilde Bonfrate, Vilma A. Sardao
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Inflammatory Mechanisms of Organ Crosstalk during Ischemic Acute Kidney Injury2011 / Laura E. White, Heitham T. Hassoun
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Functional Proteomic Profiling of Phosphodiesterases Using SeraFILE Separations Platform2012 / Amita R. Oka, Matthew P. Kuruc, Ketan M. Gujarathi, Swapan Roy
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Autoimmune Hepatitis: A Review of Current Diagnosis and Treatment2011 / Ashima Makol, Kymberly D. Watt, Vaidehi R. Chowdhary
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Perioperative management of pulmonary hypertension2010 / DeepakK Tempe
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Almanac 2011: heart failure. The national society journals present selected research that has driven recent advances in clinical cardiology2011 / A. L. Clark
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Vascular Endothelial Growth Factor Inhibition by dRK6 Causes Endothelial Apoptosis, Fibrosis, and Inflammation in the Heart via the Akt/eNOS Axis in db/db Mice2009 / C. Whee Park, H. Wook Kim, J. Hee Lim, K. Dong Yoo, S. Chung, et al.