Basic medicine topic list of research papers
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Inhibition of L-type Ca2+ current by ginsenoside Rd in rat ventricular myocytes
Abstract Background Ginsenoside Rd (GSRd), one of the most abundant ingredients of Panax ginseng, protects the heart via multiple mechanisms including the inhibition of Ca2+ influx. We intended to explore the effects of GSRd on...
2014 / Cheng Lu, Zhijun Sun, Line Wang -
Long-term treadmill training ameliorates endothelium-dependent vasorelaxation mediated by insulin and insulin-like growth factor-1 in hypertension2015 / Yi-Yuan Lin, Shin-Da Lee, Chia-Ting Su, Tsung-Lin Cheng, Ai-Lun Yang
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Interactions between sleep, stress, and metabolism: From physiological to pathological conditions
Abstract Poor sleep quality due to sleep disorders and sleep loss is highly prevalent in the modern society. Underlying mechanisms show that stress is involved in the relationship between sleep and metabolism through hypothalamic–pituitary–adrenal...
2015 / Camila Hirotsu, Sergio Tufik, Monica Levy Andersen -
Ryanodine receptor-mediated arrhythmias and sudden cardiac death
Abstract The cardiac ryanodine receptor-Ca2+ release channel (RyR2) is an essential sarcoplasmic reticulum (SR) transmembrane protein that plays a central role in excitation–contraction coupling (ECC) in cardiomyocytes. Aberrant spontaneous,...
2009 / Lynda M. Blayney, F. Anthony Lai -
Therapeutic potential of statins and the induction of heme oxygenase-1 in preeclampsia
Abstract Heme oxygenase (Hmox) is an endogenous system that offers protection against placental cytotoxic damage associated with preeclampsia. The Hmox1/carbon monoxide (CO) pathway inhibits soluble Flt-1 (sFlt-1) and soluble Endoglin (sEng). More...
2014 / Wenda Ramma, Asif Ahmed -
Noninvasive risk stratification of lethal ventricular arrhythmias and sudden cardiac death after myocardial infarction
Abstract Prediction of lethal ventricular arrhythmias leading to sudden cardiac death is one of the most important and challenging problems after myocardial infarction (MI). Identification of MI patients who are prone to ventricular tachyarrhythmias ...
2014 / Kenji Yodogawa, Wataru Shimizu -
Mitochondrial DNA disease—molecular insights and potential routes to a cure
Abstract Mitochondrial DNA diseases are common neurological conditions caused by mutations in the mitochondrial genome or nuclear genes responsible for its maintenance. Current treatments for these disorders are focussed on the management of the...
2014 / Oliver Russell, Doug Turnbull -
Association of heat shock proteins, heat shock factors and male infertility
Abstract It has been well established that heat shock proteins (HSP) and heat shock factors (HSF) are involved in wide varieties of physiological regulation process and signal pathway. Numerous members of heat shock family exhibit a...
2013 / Zi-Liang Ji, Yong-Gang Duan, Li-Sha Mou, Jean-Pierre Allam, Gerhard Haidl, et al. -
A critical review of the treatment options available for obstructive sleep apnoea: an overview of the current literature available on treatment methods for obstructive sleep apnoea and future research directions2014 / A. J. Booth, Y. Djavadkhani, N. S. Marshall
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Reducing In-Stent Restenosis
Abstract Background Drug-eluting stents reduce the incidence of in-stent restenosis, but they result in delayed arterial healing and are associated with a chronic inflammatory response and hypersensitivity reactions. Identifying...
2015 / Robert A. McDonald, Crawford A. Halliday, Ashley M. Miller, Louise A. Diver, Rachel S. Dakin, et al. -
Omega 3 fatty acid inhibition of inflammatory cytokine-mediated Connexin43 regulation in the heart2012 / Jennifer R. Baum, Elena Dolmatova, Alex Tan, Heather S. Duffy
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Novel therapeutic strategies for ischemic heart disease
Abstract Despite significant advances in the physician's ability to initiate myocardial reperfusion and salvage heart tissue, ischemic heart disease remains one of the leading causes of death in the United States. Consequently, alternative...
2014 / Adam J. Perricone, Richard S. Vander Heide -
Sleep-Disordered Breathing, Sleep Duration, and Childhood Overweight: A Longitudinal Cohort Study
Objectives To examine independent associations between sleep-disordered breathing (SDB), sleep duration from birth through 6.75 years, and body mass index (BMI) through 15 years of age in a population-based cohort. ...
2014 / Karen Bonuck, Ronald D. Chervin, Laura D. Howe -
Mapping and Ablating Ventricular Premature Contractions That Trigger Ventricular Fibrillation: Trigger Elimination and Substrate Modification2014 / AKIHIKO NOGAMI
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The late sodium current in heart failure: pathophysiology and clinical relevance2014 / Balazs Horvath, Donald M. Bers
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Similarities and Differences between the Pathogenesis and Pathophysiology of Diastolic and Systolic Heart Failure2013 / Kazuo Komamura
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Cardiovascular Function in Pulmonary Emphysema2013 / Dina Visca, Marina Aiello, Alfredo Chetta
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LPS- and LTA-Induced Expression of IL-6 and TNF- α in Neonatal and Adult Blood: Role of MAPKs and NF- κ B2014 / Lutz Koch, David Frommhold, Kirsten Buschmann, Navina Kuss, Johannes Poeschl, et al.
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The effectiveness of melatonin for promoting healthy sleep: a rapid evidence assessment of the literature2014 / Rebecca B Costello, Cynthia V Lentino, Courtney C Boyd, Meghan L O’Connell, Cindy C Crawford, et al.
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Myostatin and IGF-I signaling in end-stage human heart failure: a qRT-PCR study2015 / Júlia Baán, Zoltán V Varga, Przemyslaw Leszek, Mariusz Kuśmierczyk, Tamás Baranyai, et al.