Basic medicine topic list of research papers
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Decreased creatine kinase is linked to diastolic dysfunction in rats with right heart failure induced by pulmonary artery hypertension
Abstract Our objective was to investigate the role of creatine kinase in the contractile dysfunction of right ventricular failure caused by pulmonary artery hypertension. Pulmonary artery hypertension and right ventricular failure were induced in...
2015 / Ewan D. Fowler, David Benoist, Mark J. Drinkhill, Rachel Stones, Michiel Helmes, et al. -
Late cardioprotection of exercise preconditioning against exhaustive exercise-induced myocardial injury by up-regulatation of connexin 43 expression in rat hearts
Abstract Objective To investigate the expression of myocardium connexin 43 (Cx43) in late exercise preconditioning (LEP) cardioprotection. Methods Eight-week-old...
2015 / Kai Wang, Bai-Chao Xu, Hai-Yun Duan, Hua Zhang, Fu-Song Hu -
Altering the redox state of skeletal muscle by glutathione depletion increases the exercise-activation of PGC-12014 / N. A. Strobel, A. Matsumoto, J. M. Peake, S. A. Marsh, T.-T. Peternelj, et al.
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Safety and efficacy of exercise testing with atropine in patients with recent uncomplicated ST elevation acute myocardial infarction2012 / Filippo Sarullo, Luigi Americo, Salvatore Milia, Ignazio Brusca, Natale Faraone, et al.
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Ang (1-7) is a modulator of the vasoconstrictor actions of Ang I and Ang II2015 / J. Flores-Monroy, I. Valencia-Hernandez, L. Martinez-Aguilar
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Cell Therapy for Heart Failure With Preserved Ejection Fraction∗2016 / Barry A. Borlaug, Yogesh N.V. Reddy
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Characterization of inflammatory markers associated with systemic lupus erythematosus patients undergoing treatment
Abstract Objective To characterize the inflammatory profiles of patients with systemic lupus erythematosus receiving standard treatment compared to healthy controls. Patients and...
2016 / Rodolfo Pessato Timóteo, Douglas Cobo Micheli, Reginaldo Botelho Teodoro, Marlene Freire, Dernival Bertoncello, et al. -
Mapping of ventricular tachycardia in patients with structural heart disease
Abstract Catheter ablation is now recognized as one of the potent options to reduce the number of implantable cardioverter defibrillator (ICD) shock therapies by modifying arrhythmic substrate in patients affected by ventricular tachycardia (VT)....
2014 / Hiroya Mizuno -
Endosonography in Autoimmune Pancreatitis
Abstract Autoimmune pancreatitis is a rare disease which is hard to diagnose without a definitive histology. Therefore endosonographic experiences are quite limited and mostly down to case reports or series. Because of the lack of histologic proven...
2013 / M Hocke, A Ignee -
Redox signaling in cardiac myocytes
Abstract The heart has complex mechanisms that facilitate the maintenance of an oxygen supply–demand balance necessary for its contractile function in response to physiological fluctuations in workload as well as in response to chronic stresses such ...
2011 / Celio X.C. Santos, Narayana Anilkumar, Min Zhang, Alison C. Brewer, Ajay M. Shah -
Clinical benefit of adenosine as an adjunct to reperfusion in ST-elevation myocardial infarction patients: An updated meta-analysis of randomized controlled trials
Abstract Background Adenosine administered as an adjunct to reperfusion can reduce coronary no-reflow and limit myocardial infarct (MI) size in ST-segment elevation myocardial infarction (STEMI) patients. Whether adjunctive...
2015 / Heerajnarain Bulluck, Alex Sirker, Yoon K. Loke, David Garcia-Dorado, Derek J. Hausenloy -
Nonapeptide Hormones Oxytocin and Vasopressin Distinctly Regulate Cav1.2 L-type Calcium Channel Expression in Cardiomyocytes
Background: The neurohypophyseal hormones oxytocin (OT) and [Arg8]-vasopressin (AVP) have recently been implicated in cardiac function. This study was designed to investigate actions of OT and AVP on regulation of the voltage-gated Ca2+ channel in cardiomyocytes. ...
2012 / Masaki Morishima, Shintaro Tahara, Yan Wang, Toshihiko Kaku, Katsushige Ono -
Inflammation and Atrial Fibrillation
Abstract Atrial fibrillation (AF) is the most common sustained arrhythmia encountered in clinical practice. Accumulating evidence indicates a link between inflammation and AF, and important advances in understanding mechanisms of AF are arising from ...
2012 / Yasumi Endoh, Ikuko Endoh, Carolyn Geczy, Akihiro Nakagomi, Yoshiki Kusama, et al. -
Clinician-induced (iatrogenic) damage incurred during human infertility treatment: Detrimental effects of sperm selection methods and cryopreservation upon the viability, DNA integrity, and function of human sperm
Abstract Human infertility is becoming increasingly prevalent and is now estimated to affect 10% of couples worldwide. Although phenomenal development in assisted reproductive technology (ART) has yielded a powerful and sophisticated discipline with ...
2013 / Suseela Yelumalai, Junaid Kashir, Celine Jones, Hani Bagheri, Su Lin Oo, et al. -
Anti-Fibrotic Effects of Class I HDAC Inhibitor, Mocetinostat Is Associated with IL-6/Stat3 Signaling in Ischemic Heart Failure2015 / Hikmet Nural-Guvener, Liudmila Zakharova, Lorraine Feehery, Snjezana Sljukic, Mohamed Gaballa
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Dual Role of Endothelial Nitric Oxide Synthase in Oxidized LDL-Induced, p66Shc-Mediated Oxidative Stress in Cultured Human Endothelial Cells2014 / Yi Shi, Thomas F. Lüscher, Giovanni G. Camici
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Cytokine release assays for the prediction of therapeutic mAb safety in first-in man trials — Whole blood cytokine release assays are poorly predictive for TGN1412 cytokine storm
Abstract The therapeutic monoclonal antibody (mAb) TGN1412 (anti-CD28 superagonist) caused near-fatal cytokine release syndrome (CRS) in all six volunteers during a phase-I clinical trial. Several cytokine release assays (CRAs) with reported...
2015 / S. Vessillier, D. Eastwood, B. Fox, J. Sathish, S. Sethu, et al. -
Remote ischemic conditioning: from experimental observation to clinical application: report from the 8th Biennial Hatter Cardiovascular Institute Workshop2014 / Jack M. J. Pickard, Hans Erik Bøtker, Gabriele Crimi, Brian Davidson, Sean M. Davidson, et al.
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Ca 2+ /calmodulin-dependent protein kinase II equally induces sarcoplasmic reticulum Ca 2+ leak in human ischaemic and dilated cardiomyopathy2014 / Thomas H. Fischer, Jörg Eiringhaus, Nataliya Dybkova, Anna Förster, Jonas Herting, et al.
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Peripartum cardiomyopathy: Euro Observational Research Program2014 / M. F. Hoes, I. van Hagen, F. Russo, D. J. Van Veldhuisen, M. P. Van den Berg, et al.