Basic medicine topic list of research papers
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The role of TDP1 and APTX in mitochondrial DNA repair
Abstract In recent years, our knowledge surrounding mammalian mitochondrial DNA (mtDNA) damage and repair has increased significantly. Greater insights into the factors that govern mtDNA repair are being elucidated, thus contributing to an increase...
2013 / Martin Meagher, Robert N. Lightowlers -
A new paradigm for the treatment of volume overload in heart failure-combined effect of tolvaptan with furosemide2013 / Hiroshi Okamoto
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Surgical Ablation of Atrial Fibrillation2012 / Taijiro Sueda
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The Role of Echocardiography in Cardiac Resynchronization Therapy
For patients with medically refractive heart failure and wide QRS interval, cardiac resynchronization therapy has been established as an adjunctive therapy. Echocardiography is a useful method to identify and assess patients who are considered for cardiac...
2008 / Chung-Huo Chen, Wen-Chin Ko, Chih-Hui Chin, Paul H. Chen -
Brain-derived neurotrophic factor (BDNF) as a potential mechanism of the effects of acute exercise on cognitive performance
Abstract The literature shows that improvements in cognitive performance may be observed following an acute bout of exercise. However, evidence in support of the biological mechanisms of this effect is still limited. Findings from both rodent and...
2014 / Aaron T. Piepmeier, Jennifer L. Etnier -
Acute Cardiotoxicity Evaluation of the Marine Biotoxins OA, DTX-1 and YTX2015 / Sara Ferreiro, Cristina Carrera, Natalia Vilariño, M. Louzao, Germán Santamarina, et al.
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Macrophage activation and its role in repair and pathology after spinal cord injury
Abstract The injured spinal cord does not heal properly. In contrast, tissue repair and functional recovery occur after skin or muscle injuries. The reason for this dichotomy in wound repair is unclear but inflammation, and specifically macrophage...
2015 / John C. Gensel, Bei Zhang -
The Influence of Ethnicity on Warfarin Dosage Requirements in the Chilean Population
Abstract Background Vitamin K antagonists are drugs that are widely prescribed around the world and their use has helped improve the prognosis of patients with thromboembolic disease. However, a high interindividual variability has ...
2015 / Valeska Subiabre, Ivan Palomo, Neftalí Guzmán, Eduardo Retamales, Hugo Henríquez, et al. -
Protective Effect of Focal Adhesion Kinase against Skeletal Muscle Reperfusion Injury after Acute Limb Ischemia
Objectives In cardiac muscle, ischemia reperfusion (IR) injury is attenuated by mitochondrial function, which may be upregulated by focal adhesion kinase (FAK). The aim of this study was to determine whether increased FAK levels reduced...
2014 / M. Flück, R.S. von Allmen, C. Ferrié, H. Tevaearai, F. Dick -
Exposure to occupational antigens might predispose to IgG4-related disease2014 / Lucas J. Maillette de Buy Wenniger, Emma L. Culver, Ulrich Beuers
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Melanocortin Peptides: Potential Targets in Systemic Lupus Erythematosus2014 / Lisa Carole Loram, Melissa Elizabeth Culp, Erin Corey Connolly-Strong, Sheila Sturgill-Koszycki
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Animal models in translational medicine: Validation and prediction
Abstract Despite large investments in drug development, the overall success rate of drugs during clinical development remains low. One prominent explanation is flawed preclinical research, in which the use and outcome of animal models is pivotal to...
2014 / Tinneke Denayer, Thomas Stöhr, Maarten Van Roy -
Protective Effects of Berberine on Isoproterenol-Induced Acute Myocardial Ischemia in Rats through Regulating HMGB1-TLR4 Axis2014 / Tianzhu Zhang, Shihai Yang, Juan Du
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QiShenYiQi Pills, a compound in Chinese medicine, protects against pressure overload-induced cardiac hypertrophy through a multi-component and multi-target mode2015 / Yuan-Yuan Chen, Quan Li, Chun-Shui Pan, Li Yan, Jing-Yu Fan, et al.
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Targeting the orexinergic system: Mainly but not only for sleep-wakefulness therapies
Abstract Orexin receptors belong to the big family of G protein coupled receptors (GPCRs) that constitute the main targets in the modern pharmacological approaches. Although the orexinergic system is involved in a variety of processes, treating...
2014 / Abdelaziz Ghanemi, Xintian Hu -
Effects of exercise training on cardiovascular adrenergic system2013 / Dario Leosco, Valentina Parisi, Grazia D. Femminella, Roberto Formisano, Laura Petraglia, et al.
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Exhaled Nitric Oxide as a Biomarker in COPD and Related Comorbidities2014 / Mario Malerba, Alessandro Radaeli, Alessia Olivini, Giovanni Damiani, Beatrice Ragnoli, et al.
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Autoantibodies Targeting AT1 Receptor from Patients with Acute Coronary Syndrome Upregulate Proinflammatory Cytokines Expression in Endothelial Cells Involving NF- κ B Pathway2014 / Weijuan Li, Zhi Li, Yaoqi Chen, Songhai Li, Yuanyuan Lv, et al.
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Changes in Cardiopulmonary Reserve and Peripheral Arterial Function Concomitantly with Subclinical Inflammation and Oxidative Stress in Patients with Heart Failure with Preserved Ejection Fraction2014 / Damien Vitiello, François Harel, Rhian M. Touyz, Martin G. Sirois, Joel Lavoie, et al.
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Exercise and Cardiovascular Diseases2014 / Massimo Villella, Alessandro Villella